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t(11;14)(q23;q32) IGH/DDX6

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 1364

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma|Nodal marginal zone B-cell lymphoma

Genes involved and Proteins

Gene NameIGH
Location 14q32.33
Gene NameDDX6
Location 11q23.3

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute


The RCK gene associated with t(11;14) translocation is distinct from the MLL/ALL-1 gene with t(4;11) and t(11;19) translocations
Akao Y, Seto M, Yamamoto K, Iida S, Nakazawa S, Inazawa J, Abe T, Takahashi T, Ueda R
Cancer Res 1992 Nov 1;52(21):6083-7
PMID 1394235
Chromosomal abnormalities in acute lymphoblastic leukemia
Bloomfield CD, Lindquist LL, Arthur D, McKenna RW, LeBien TW, Nesbit ME, Peterson BA
Cancer Res 1981 Nov;41(11 Pt 2):4838-43
PMID 7028252
t(11;14)(q23;q32) involving IGH and DDX6 in nodal marginal zone lymphoma
Stary S, Vinatzer U, Müllauer L, Raderer M, Birner P, Streubel B
Genes Chromosomes Cancer 2013 Jan;52(1):33-43
PMID 22965301

Translocations implicated (Data extracted from papers in the Atlas)

 t(11;14)(q23;q32) IGH/DDX6

External links

IGH (14q32.33) DDX6 (11q23.3)

Mitelman databaset(11;14)(q23;q32) [Case List]    t(11;14)(q23;q32) [Transloc-MCList] IGH/DDX6 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:24:54 CET 2018

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