t(11;18)(q23;q21) KMT2A/ME2

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute myeloid leukemia, NOS

Genes Involved and Proteins

Gene name
KMT2A
Location
11q23.3
Gene name
ME2
Location
18q21.2

Highly cited references

Pubmed IDYearTitleCitations
265566902015Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (MLL-ME2) fusion gene.0

Bibliography

Pubmed IDLast YearTitleAuthors
236289582013The MLL recombinome of acute leukemias in 2013.Meyer C et al
265566902015Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (MLL-ME2) fusion gene.Szotkowski T et al

Summary

Fusion gene

KMT2A/ME2 KMT2A (11q23.3) ME2 (18q21.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(11;18)(q23;q21) KMT2A/ME2

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2886/t(11;18)(q23;q21)-kmt2a-me2