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t(11;21)(q12;q22) RUNX1/LPXN

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3483
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloid leukemia, NOS

Genes involved and Proteins

Gene NameRUNX1
Location 21q22.12
Gene NameLPXN
Location 11q12.1

Bibliography

LPXN, a member of the paxillin superfamily, is fused to RUNX1 in an acute myeloid leukemia patient with a t(11;21)(q12;q22) translocation
Dai HP, Xue YQ, Zhou JW, Li AP, Wu YF, Pan JL, Wang Y, Zhang J
Genes Chromosomes Cancer 2009 Dec;48(12):1027-36
PMID 19760607
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(11;21)(q12;q22) RUNX1/LPXN

External links

RUNX1 (21q22.12) LPXN (11q12.1)

Mitelman databaset(11;21)(q12;q22) [Case List]    t(11;21)(q12;q22) [Transloc-MCList] RUNX1/LPXN [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Nov 6 14:08:10 CET 2018


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