| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 3082 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
| Genes involved and Proteins |
| Gene Name | PDE9A |
| Location | 21q22.3 |
| Gene Name | MUS81 |
| Location | 11q13.1 |
| Bibliography |
| Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancy |
| Sinclair PB, Parker H, An Q, Rand V, Ensor H, Harrison CJ, Strefford JC |
| Hum Mol Genet 2011 Jul 1;20(13):2591-602 |
| PMID 21487021 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(11;21)(q13;q22) PDE9A/MUS81 | |
| External links |
| Mitelman database | t(11;21)(q13;q22) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:28:46 CET 2020 |
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