t(11;21)(q13;q22) PDE9A/MUS81

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	3082
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene Name	PDE9A
Location	21q22.3

Gene Name	MUS81
Location	11q13.1

Bibliography

Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancy

Sinclair PB, Parker H, An Q, Rand V, Ensor H, Harrison CJ, Strefford JC

Hum Mol Genet 2011 Jul 1;20(13):2591-602

PMID 21487021

Translocations implicated (Data extracted from papers in the Atlas)

	t(11;21)(q13;q22) PDE9A/MUS81

External links

PDE9A (21q22.3) MUS81 (11q13.1)

Mitelman database	t(11;21)(q13;q22) [Case List]    t(11;21)(q13;q22) [Transloc-MCList] PDE9A/MUS81 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon May 11 15:54:56 CEST 2020

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