Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 3082 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
Genes involved and Proteins |
Gene Name | PDE9A |
Location | 21q22.3 |
Gene Name | MUS81 |
Location | 11q13.1 |
Bibliography |
Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancy |
Sinclair PB, Parker H, An Q, Rand V, Ensor H, Harrison CJ, Strefford JC |
Hum Mol Genet 2011 Jul 1;20(13):2591-602 |
PMID 21487021 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(11;21)(q13;q22) PDE9A/MUS81 | |
External links |
Mitelman database | t(11;21)(q13;q22) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:28:46 CET 2020 |
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