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t(11;22)(q24;q12) EWSR1/FLI1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2716

Clinics and Pathology

Disease Ewing sarcoma

Genes involved and Proteins

Gene NameEWSR1
Location 22q12.2
Gene NameFLI1
Location 11q24.3

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Association of EWS-FLI1 type 1 fusion with lower proliferative rate in Ewing's sarcoma
de Alava E, Panizo A, Antonescu CR, Huvos AG, Pardo-Mindán FJ, Barr FG, Ladanyi M
Am J Pathol 2000 Mar;156(3):849-55
PMID 10702401
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(11;22)(q24;q12) EWSR1/FLI1

External links

EWSR1 (22q12.2) FLI1 (11q24.3)

Mitelman databaset(11;22)(q24;q12) [Case List]    t(11;22)(q24;q12) [Transloc-MCList] EWSR1/FLI1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:25:01 CET 2018


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