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t(12;13)(p13;q12) FLT3/ETV6

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2730

Clinics and Pathology

Disease Acute myelomonocytic leukemia (FAB type M4)

Genes involved and Proteins

Gene NameFLT3
Location 13q12.2
Gene NameETV6
Location 12p13.2

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Double-hit of FLT3 gene in a fatal case of acute myemonocytic leukaemia
Lu G, Schulz RA, Bueso-Ramos CE, Cortes JE, Iris Wang X, Medeiros LJ, Yin CC
J Clin Pathol 2013 Sep;66(9):826-9
PMID 23703854
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(12;13)(p13;q12) FLT3/ETV6

External links

FLT3 (13q12.2) ETV6 (12p13.2)

Mitelman databaset(12;13)(p13;q12) [Case List]    t(12;13)(p13;q12) [Transloc-MCList] FLT3/ETV6 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:22:47 CET 2018


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