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t(12;13)(p13;q12) FLT3/ETV6

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2730
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myelomonocytic leukemia (FAB type M4)

Genes involved and Proteins

Gene NameFLT3
Location 13q12.2
Gene NameETV6
Location 12p13.2

Bibliography

Double-hit of FLT3 gene in a fatal case of acute myemonocytic leukaemia
Lu G, Schulz RA, Bueso-Ramos CE, Cortes JE, Iris Wang X, Medeiros LJ, Yin CC
J Clin Pathol 2013 Sep;66(9):826-9
PMID 23703854
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(12;13)(p13;q12) FLT3/ETV6

External links

FLT3 (13q12.2) ETV6 (12p13.2)

Mitelman databaset(12;13)(p13;q12) [Case List]    t(12;13)(p13;q12) [Transloc-MCList] FLT3/ETV6 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:22:04 CEST 2018


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