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t(12;17)(p13;q12) TAF15/ZNF384

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3486
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma|Acute monoblastic leukemia with differentiation (FAB type M5b)|Acute myeloblastic leukemia without maturation (FAB type M1)|Bilineage or biphenotypic leukemia

Genes involved and Proteins

Gene NameTAF15
Location 17q12
Gene NameZNF384
Location 12p13.31

Bibliography

Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia
Martini A, La Starza R, Janssen H, Bilhou-Nabera C, Corveleyn A, Somers R, Aventin A, Foà R, Hagemeijer A, Mecucci C, Marynen P
Cancer Res 2002 Oct 1;62(19):5408-12
PMID 12359745
 
Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia
Martini A, La Starza R, Janssen H, Bilhou-Nabera C, Corveleyn A, Somers R, Aventin A, Foà R, Hagemeijer A, Mecucci C, Marynen P
Cancer Res 2002 Oct 1;62(19):5408-12
PMID 12359745
 
Identification of the TAF15-ZNF384 fusion gene in two new cases of acute lymphoblastic leukemia with a t(12;17)(p13;q12)
Nyquist KB, Thorsen J, Zeller B, Haaland A, Trøen G, Heim S, Micci F
Cancer Genet 2011 Mar;204(3):147-52
PMID 21504714
 
Lineage switch from pro-B acute lymphoid leukemia to acute myeloid leukemia in a case with t(12;17)(p13;q11)/TAF15-ZNF384 rearrangement
Grammatico S, Vitale A, La Starza R, Gorello P, Angelosanto N, Negulici AD, De Propris MS, Nanni M, Meloni G, Mecucci C, Foà R
Leuk Lymphoma 2013 Aug;54(8):1802-5
PMID 23206227
 
Mixed Phenotype Acute Leukemia with t(12;17)(p13;q21)/TAF15-ZNF384 and Other Chromosome Abnormalities
Yamamoto K, Kawamoto S, Mizutani Y, Yakushijin K, Yamashita T, Nakamachi Y, Kawano S, Hayashi Y, Matsuoka H, Minami H
Cytogenet Genome Res 2016;149(3):165-170
PMID 27607436
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(12;17)(p13;q12) TAF15/ZNF384

External links

TAF15 (17q12) ZNF384 (12p13.31)

Mitelman databaset(12;17)(p13;q12) [Case List]    t(12;17)(p13;q12) [Transloc-MCList] TAF15/ZNF384 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Nov 6 14:08:19 CET 2018


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