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t(12;21)(q12;q22) RUNX1/CPNE8

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3161
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloblastic leukemia with maturation (FAB type M2)

Genes involved and Proteins

Gene NameRUNX1
Gene NameCPNE8
Location 12q12

Bibliography

Fusion of AML1/Runx1 to copine VIII, a novel member of the copine family, in an aggressive acute myelogenous leukemia with t(12;21) translocation
Ramsey H, Zhang DE, Richkind K, Burcoglu-O'Ral A, Hromas R
Leukemia 2003 Aug;17(8):1665-6
PMID 12886257
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(12;21)(q12;q22) RUNX1/CPNE8

External links

RUNX1 () CPNE8 (12q12)

Mitelman databaset(12;21)(q12;q22) [Case List]    t(12;21)(q12;q22) [Transloc-MCList] RUNX1/CPNE8 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Mon May 14 13:45:17 CEST 2018


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