FLT3/FLT3 (13q12)

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute megakaryoblastic leukemia (FAB type M7)

Genes Involved and Proteins

Gene name
Location
13q12.2
Gene name
Location
13q12.2

Highly cited references

Pubmed IDYearTitleCitations
246393462014Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells.13
171568412007Soluble phosphorylated fms-like tyrosine kinase III. FLT3 protein in patients with acute myeloid leukemia (AML).2

Bibliography

Pubmed IDLast YearTitleAuthors
281127372017Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes.de Rooij JD et al

Summary

Fusion gene

FLT3/FLT3 FLT3 (13q12.2) FLT3 (13q12.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Citation

Philippe Dessen ; Jean-Loup Huret

FLT3/FLT3 (13q12)

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2731/flt3-flt3-(13q12)