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t(14;16)(q32;q24) IGH/IRF8

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 1669
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Diffuse large B-cell lymphoma

Genes involved and Proteins

Gene NameIGH
Location 14q32.33
Gene NameIRF8

Bibliography

IRF8 is associated with germinal center B-cell-like type of diffuse large B-cell lymphoma and exceptionally involved in translocation t(14;16)(q32
Tinguely M, Thies S, Frigerio S, Reineke T, Korol D, Zimmermann DR
33;q24 1)
PMID 23573829
 
A capture-sequencing strategy identifies IRF8, EBF1, and APRIL as novel IGH fusion partners in B-cell lymphoma
Bouamar H, Abbas S, Lin AP, Wang L, Jiang D, Holder KN, Kinney MC, Hunicke-Smith S, Aguiar RC
Blood 2013 Aug 1;122(5):726-33
PMID 23775715
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(14;16)(q32;q24) IGH/IRF8

External links

IGH (14q32.33) IRF8 ()

Mitelman databaset(14;16)(q32;q24) [Case List]    t(14;16)(q32;q24) [Transloc-MCList] IGH/IRF8 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon Jul 9 10:15:58 CEST 2018


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