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t(14;19)(q32;q13) IGH/SPIB

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2811

Clinics and Pathology

Disease Diffuse large B-cell lymphoma

Genes involved and Proteins

Gene NameIGH
Location 14q32.33
Gene NameSPIB
Location 19q13.33

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Interphase detection of immunoglobulin heavy chain gene translocations with specific oncogene loci in 173 patients with B-cell lymphoma
Tamura A, Miura I, Iida S, Yokota S, Horiike S, Nishida K, Fujii H, Nakamura S, Seto M, Ueda R, Taniwaki M
Cancer Genet Cytogenet 2001 Aug;129(1):1-9
PMID 11520558
 
Bcl-3/IgH translocation (14;19)(q32;q13) in non-Hodgkin's lymphomas
Au WY, Horsman DE, Ohno H, Klasa RJ, Gascoyne RD
Leuk Lymphoma 2002 Apr;43(4):813-6
PMID 12153169
 
Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma
Lenz G, Nagel I, Siebert R, Roschke AV, Sanger W, Wright GW, Dave SS, Tan B, Zhao H, Rosenwald A, Muller-Hermelink HK, Gascoyne RD, Campo E, Jaffe ES, Smeland EB, Fisher RI, Kuehl WM, Chan WC, Staudt LM
J Exp Med 2007 Mar 19;204(3):633-43
PMID 17353367
 
Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas
Otto C, Scholtysik R, Schmitz R, Kreuz M, Becher C, Hummel M, Rosenwald A, Trümper L, Klapper W, Siebert R, Küppers R; “Molecular Mechanisms in Malignant Lymphomas” Network Project
Genes Chromosomes Cancer 2016 Dec;55(12):932-943
PMID 27356265
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(14;19)(q32;q13) IGH/SPIB

External links

IGH (14q32.33) SPIB (19q13.33)

Mitelman databaset(14;19)(q32;q13) [Case List]    t(14;19)(q32;q13) [Transloc-MCList] IGH/SPIB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:23:03 CET 2018


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