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t(15;16)(q21;p13) CIITA/C15orf65

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2605

Clinics and Pathology

Disease Hodgkin disease, NOS:Mediastinal large B-cell lymphoma

Genes involved and Proteins

Gene NameCIITA
Location 16p13.13
Gene NameC15orf65
Location 15q21.3

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers
Steidl C, Shah SP, Woolcock BW, Rui L, Kawahara M, Farinha P, Johnson NA, Zhao Y, Telenius A, Neriah SB, McPherson A, Meissner B, Okoye UC, Diepstra A, van den Berg A, Sun M, Leung G, Jones SJ, Connors JM, Huntsman DG, Savage KJ, Rimsza LM, Horsman DE, Staudt LM, Steidl U, Marra MA, Gascoyne RD
Nature 2011 Mar 17;471(7338):377-81
PMID 21368758
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(15;16)(q21;p13) CIITA/C15orf65

External links

CIITA (16p13.13) C15orf65 (15q21.3)

Mitelman databaset(15;16)(q21;p13) [Case List]    t(15;16)(q21;p13) [Transloc-MCList] CIITA/C15orf65 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:25:22 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.