| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 3180 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
| Genes involved and Proteins |
| Gene Name | RUNX1 |
| Location | 21q22.12 |
| Gene Name | SV2B |
| Location | 15q26.1 |
| Bibliography |
| Identification of a novel fusion gene involving RUNX1 and the antisense strand of SV2B in a BCR-ABL1-positive acute leukemia |
| Giguère A, Hébert J |
| Genes Chromosomes Cancer 2013 Dec;52(12):1114-22 |
| PMID 24123676 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(15;21)(q26;q22) RUNX1/SV2B | |
| External links |
| Mitelman database | t(15;21)(q26;q22) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:29:05 CET 2020 |
For comments and suggestions or contributions, please contact us