t(15;21)(q26;q22) RUNX1/SV2B

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	3180
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene Name	RUNX1
Location	21q22.12

Gene Name	SV2B
Location	15q26.1

Bibliography

Identification of a novel fusion gene involving RUNX1 and the antisense strand of SV2B in a BCR-ABL1-positive acute leukemia

Giguère A, Hébert J

Genes Chromosomes Cancer 2013 Dec;52(12):1114-22

PMID 24123676

Translocations implicated (Data extracted from papers in the Atlas)

	t(15;21)(q26;q22) RUNX1/SV2B

External links

RUNX1 (21q22.12) SV2B (15q26.1)

Mitelman database	t(15;21)(q26;q22) [Case List]    t(15;21)(q26;q22) [Transloc-MCList] RUNX1/SV2B [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 12 17:03:16 CEST 2019

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