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t(15;21)(q26;q22) RUNX1/SV2B

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3180
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameRUNX1
Location 21q22.12
Gene NameSV2B
Location 15q26.1

Bibliography

Identification of a novel fusion gene involving RUNX1 and the antisense strand of SV2B in a BCR-ABL1-positive acute leukemia
Giguère A, Hébert J
Genes Chromosomes Cancer 2013 Dec;52(12):1114-22
PMID 24123676
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(15;21)(q26;q22) RUNX1/SV2B

External links

RUNX1 (21q22.12) SV2B (15q26.1)

Mitelman databaset(15;21)(q26;q22) [Case List]    t(15;21)(q26;q22) [Transloc-MCList] RUNX1/SV2B [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Nov 6 14:08:46 CET 2018


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