Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 3180 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
Genes involved and Proteins |
Gene Name | RUNX1 |
Location | 21q22.12 |
Gene Name | SV2B |
Location | 15q26.1 |
Bibliography |
Identification of a novel fusion gene involving RUNX1 and the antisense strand of SV2B in a BCR-ABL1-positive acute leukemia |
Giguère A, Hébert J |
Genes Chromosomes Cancer 2013 Dec;52(12):1114-22 |
PMID 24123676 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(15;21)(q26;q22) RUNX1/SV2B | |
External links |
Mitelman database | t(15;21)(q26;q22) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:29:05 CET 2020 |
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