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t(16;21)(p11;q22) ERG/FUS

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2690

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameERG
Location 8p23.3
Gene NameFUS
Location 16p11.2

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease
Kanazawa T, Ogawa C, Taketani T, Taki T, Hayashi Y, Morikawa A
Leuk Lymphoma 2005 Dec;46(12):1833-5
 
Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia
Liu YF, Wang BY, Zhang WN, Huang JY, Li BS, Zhang M, Jiang L, Li JF, Wang MJ, Dai YJ, Zhang ZG, Wang Q, Kong J, Chen B, Zhu YM, Weng XQ, Shen ZX, Li JM, Wang J, Yan XJ, Li Y, Liang YM, Liu L, Chen XQ, Zhang WG, Yan JS, Hu JD, Shen SH, Chen J, Gu LJ, Pei D, Li Y, Wu G, Zhou X, Ren RB, Cheng C, Yang JJ, Wang KK, Wang SY, Zhang J, Mi JQ, Pui CH, Tang JY, Chen Z, Chen SJ
EBioMedicine 2016 Jun;8:173-183
PMID 27428428
 
Multiplex reverse transcription-polymerase chain reaction for simultaneous screening of 29 translocations and chromosomal aberrations in acute leukemia
Pallisgaard N, Hokland P, Riishøj DC, Pedersen B, Jørgensen P
Blood 1998 Jul 15;92(2):574-88
PMID 9657758
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(16;21)(p11;q22) ERG/FUS

External links

ERG (8p23.3) FUS (16p11.2)

Mitelman databaset(16;21)(p11;q22) [Case List]    t(16;21)(p11;q22) [Transloc-MCList] ERG/FUS [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:23:11 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.