t(17;19)(q22;q13) MPO/ZNF296

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute myeloblastic leukemia without maturation (FAB type M1)

Genes Involved and Proteins

Gene name
MPO
Location
17q22
Gene name
ZNF296
Location
19q13.32

Bibliography

Pubmed IDLast YearTitleAuthors
192559752009Overexpression of ZNF342 by juxtaposition with MPO promoter/enhancer in the novel translocation t(17;19)(q23;q13.32) in pediatric acute myeloid leukemia and analysis of ZNF342 expression in leukemia.Poland KS et al

Summary

Fusion gene

MPO/ZNF296 MPO (17q22) ZNF296 (19q13.32)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

t(17;19)(q22;q13) MPO/ZNF296

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/1578/t(17;19)(q22;q13)-mpo-znf296