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t(X;14)(q22;q32) RNA28S5/BCL11B

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3148

Clinics and Pathology

Disease Bilineage or biphenotypic leukemia

Genes involved and Proteins

Gene Name
Location 22p12 not on reference assembly
Gene NameBCL11B
Location 14q32.2

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Identification of novel fusion genes with 28S ribosomal DNA in hematologic malignancies
Kobayashi S, Taki T, Nagoshi H, Chinen Y, Yokokawa Y, Kanegane H, Matsumoto Y, Kuroda J, Horiike S, Nishida K, Taniwaki M
Int J Oncol 2014 Apr;44(4):1193-8
PMID 24504345
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(X;14)(q22;q32) RNA28S5/BCL11B

External links

RNA28S5 (22p12 not on

Mitelman databaset(X;14)(q22;q32) [Case List]    t(X;14)(q22;q32) [Transloc-MCList] RNA28S5/BCL11B [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:25:49 CET 2018


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jlhuret@AtlasGeneticsOncology.org.