| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 3278 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Nonneoplastic hematologic disorder/lesion|T-prolymphocytic leukemia |
| Genes involved and Proteins |
| Gene Name | TRA |
| Location | 14q11.2 |
| Gene Name | MTCP1 |
| Location | Xq28 |
| Bibliography |
| A gene on chromosome Xq28 associated with T-cell prolymphocytic leukemia in two patients with ataxia telangiectasia |
| Thick J, Mak YF, Metcalfe J, Beatty D, Taylor AM |
| Leukemia 1994 Apr;8(4):564-73 |
| PMID 8152252 |
| MTCP-1: a novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations |
| Stern MH, Soulier J, Rosenzwajg M, Nakahara K, Canki-Klain N, Aurias A, Sigaux F, Kirsch IR |
| Oncogene 1993 Sep;8(9):2475-83 |
| PMID 8361760 |
| MTCP-1: a novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations |
| Stern MH, Soulier J, Rosenzwajg M, Nakahara K, Canki-Klain N, Aurias A, Sigaux F, Kirsch IR |
| Oncogene 1993 Sep;8(9):2475-83 |
| PMID 8361760 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(X;14)(q28;q11) TRA/MTCP1 | |
| External links |
| Mitelman database | t(X;14)(q28;q11) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Sep 7 15:10:48 CEST 2020 |
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