t(X;14)(q28;q11) TRA/MTCP1

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	3278
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Nonneoplastic hematologic disorder/lesion|T-prolymphocytic leukemia

Genes involved and Proteins

Gene Name	TRA
Location	14q11.2

Gene Name	MTCP1
Location	Xq28

Bibliography

A gene on chromosome Xq28 associated with T-cell prolymphocytic leukemia in two patients with ataxia telangiectasia

Thick J, Mak YF, Metcalfe J, Beatty D, Taylor AM

Leukemia 1994 Apr;8(4):564-73

PMID 8152252

MTCP-1: a novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations

Stern MH, Soulier J, Rosenzwajg M, Nakahara K, Canki-Klain N, Aurias A, Sigaux F, Kirsch IR

Oncogene 1993 Sep;8(9):2475-83

PMID 8361760

MTCP-1: a novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations

Stern MH, Soulier J, Rosenzwajg M, Nakahara K, Canki-Klain N, Aurias A, Sigaux F, Kirsch IR

Oncogene 1993 Sep;8(9):2475-83

PMID 8361760

Translocations implicated (Data extracted from papers in the Atlas)

	t(X;14)(q28;q11) TRA/MTCP1

External links

TRA (14q11.2) MTCP1 (Xq28)

Mitelman database	t(X;14)(q28;q11) [Case List]    t(X;14)(q28;q11) [Transloc-MCList] TRA/MTCP1 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Jul 8 15:31:16 CEST 2019

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