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t(X;14)(q28;q11) TRA/MTCP1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3278

Clinics and Pathology

Disease Nonneoplastic hematologic disorder/lesion:T-prolymphocytic leukemia

Genes involved and Proteins

Gene NameTRA
Location 10q26.13
Gene NameMTCP1
Location Xq28

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Molecular analysis of a new translocation, t(X;14)(q28;q11), in premalignancy and in leukaemia associated with ataxia telangiectasia
Thick J, Sherrington PD, Fisch P, Taylor AM, Rabbitts TH
Genes Chromosomes Cancer 1992 Nov;5(4):321-5
PMID 1283320
 
A gene on chromosome Xq28 associated with T-cell prolymphocytic leukemia in two patients with ataxia telangiectasia
Thick J, Mak YF, Metcalfe J, Beatty D, Taylor AM
Leukemia 1994 Apr;8(4):564-73
PMID 8152252
 
MTCP-1: a novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations
Stern MH, Soulier J, Rosenzwajg M, Nakahara K, Canki-Klain N, Aurias A, Sigaux F, Kirsch IR
Oncogene 1993 Sep;8(9):2475-83
PMID 8361760
 
MTCP-1: a novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations
Stern MH, Soulier J, Rosenzwajg M, Nakahara K, Canki-Klain N, Aurias A, Sigaux F, Kirsch IR
Oncogene 1993 Sep;8(9):2475-83
PMID 8361760
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(X;14)(q28;q11) TRA/MTCP1

External links

TRA (10q26.13) MTCP1 (Xq28)

Mitelman databaset(X;14)(q28;q11) [Case List]    t(X;14)(q28;q11) [Transloc-MCList] TRA/MTCP1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:23:31 CET 2018


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