Atlas of Genetics and Cytogenetics in Oncology and Haematology


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t(1;7)(q21;q22)

Clinics and Pathology

Disease Diffuse large B-cell lymphoma (DLBCL)
Epidemiology only 2 cases so far, aged 43 and 66 yrs; 1 male and 1 female patient
Pathology the 2 cases were centroblastic
Prognosis patients died at 10 mths and 33 mths

Cytogenetics

Cytogenetics Morphological unbalanced form der(1)t(1;7) in one case
Cytogenetics Molecular the anomaly had been uncovered by SKY

Genes involved and Proteins

Note genes involved are yet unknown

External links

Other databaset(1;7)(q21;q22) Mitelman database (CGAP - NCBI)
Other databaset(1;7)(q21;q22) CancerChromosomes (NCBI)

To be noted

Additional cases are needed to delineate the epidemiology of this rare entity:
you are welcome to submit a paper to our new Case Report section.

Bibliography

Spectral karyotyping identifies new rearrangements, translocations, and clinical associations in diffuse large B-cell lymphoma.
Nanjangud G, Rao PH, Hegde A, Teruya-Feldstein J, Donnelly G, Qin J, Jhanwar SC, Zelenetz AD, Chaganti RS
Blood. 2002 ; 99 (7) : 2554-2561.
PMID 11895793
 

Contributor(s)

Written07-2002Jean-Loup Huret

Citation

This paper should be referenced as such :
Huret JL . t(1;7)(q21;q22). Atlas Genet Cytogenet Oncol Haematol. July 2002 .
URL : http://AtlasGeneticsOncology.org/Anomalies/t0107q21q22ID1252.html

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon May 12 18:11:52 2008


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