t(3;8)(q21;q24) in myeloid malignancies
2008-06-01 Jean-Loup Huret Affiliation1.Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France
Clinics and Pathology
Disease
Acute myeloid leukemia (AML)
Epidemiology
Three patients to date, a 9-year-old girl with M4-AML, a 48-year-old male patient with M5-AML, and a 74-year-old female patient with therapy related AML(t-AML), M1 subtype, having occurred after treatment of a breast cancer (Haltrich et al., 2006; Charrin et al., 2002; Lindvall et al., 2001).
Prognosis
No individual data.
Note
Genes involved in this translocation are unknown.
Genes Involved and Proteins
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 11960392 | 2002 | Structural rearrangements of chromosome 3 in 57 patients with acute myeloid leukemia: clinical, hematological and cytogenetic features. | Charrin C et al |
| 16405433 | 2006 | Multipoint interphase FISH analysis of chromosome 3 abnormalities in 28 childhood AML patients. | Haltrich I et al |
| 11694401 | 2001 | Molecular cytogenetic characterization of acute myeloid leukemia and myelodysplastic syndromes with multiple chromosome rearrangements. | Lindvall C et al |
Citation
Jean-Loup Huret
t(3;8)(q21;q24) in myeloid malignancies
Atlas Genet Cytogenet Oncol Haematol. 2008-06-01
Online version: http://atlasgeneticsoncology.org/haematological/1249/t(3;8)(q21;q24)-in-myeloid-malignancies
