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t(3;14)(q21;q32)

Clinics and Pathology

Disease Diffuse large B-cell lymphoma (DLBCL)
Epidemiology only 2 cases so far, aged 73 and 83 yrs, 1 male and 1 female patients
Prognosis 5 mths+ and lost to follow up

Cytogenetics

Cytogenetics Morphological unbalanced form der(14) t(3;14) in 1 case, three way translocation t(1;3.14) in the other case.
Cytogenetics Molecular the anomaly had been uncovered by SKY

External links

Other databaset(3;14)(q21;q32) Mitelman database (CGAP - NCBI)
Other databaset(3;14)(q21;q32) CancerChromosomes (NCBI)

To be noted

Additional cases are needed to delineate the epidemiology of this rare entity:
you are welcome to submit a paper to our new Case Report section.

Bibliography

Spectral karyotyping identifies new rearrangements, translocations, and clinical associations in diffuse large B-cell lymphoma.
Nanjangud G, Rao PH, Hegde A, Teruya-Feldstein J, Donnelly G, Qin J, Jhanwar SC, Zelenetz AD, Chaganti RS
Blood. 2002 ; 99 (7) : 2554-2561.
PMID 11895793
 

Contributor(s)

Written07-2002Jean-Loup Huret

Citation

This paper should be referenced as such :
Huret JL . t(3;14)(q21;q32). Atlas Genet Cytogenet Oncol Haematol. July 2002 .
URL : http://AtlasGeneticsOncology.org/Genes/t0314q21q32ID1250.html

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indexed on : Mon Aug 11 21:20:02 2008


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