| Written | 1999-03 | Nyla A. Heerema |
| The Ohio State University, Division of Clinical Pathology, Department of Pathology, 167 Hamilton Hall, 1645 Neil Ave, Columbus, OH 43210, USA |
| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| ICD-Morpho | 9811/3 B lymphoblastic leukaemia/lymphoma, NOS |
| Atlas_Id | 1149 |
| Clinics and Pathology |
| Disease | B-cell, precursor ALL |
| Phenotype / cell stem origin | L1, CD10+/-, CD24+ |
| Epidemiology | 5 reported cases; Infant ALL, age 1.5-7 months at diagnosis |
| Prognosis | CR in all cases; 1 CNS relapse |
| Cytogenetics |
| Cytogenetics Morphological | t(5;15)(p15;q11-13) |
| Cytogenetics Molecular | not done |
| Additional anomalies | +14; +22 one case each |
| Variants | none reported |
| To be noted |
| Additional cases are needed to delineate the epidemiology of this rare entity: you are welcome to submit a paper to our new Case Report section. |
| Bibliography |
| Cytogenetic features of infants less than 12 months of age at diagnosis of acute lymphoblastic leukemia: impact of the 11q23 breakpoint on outcome: a report of the Childrens Cancer Group. |
| Heerema NA, Arthur DC, Sather H, Albo V, Feusner J, Lange BJ, Steinherz PG, Zeltzer P, Hammond D, Reaman GH |
| Blood. 1994 ; 83 (8) : 2274-2284. |
| PMID 8161794 |
| Citation |
| This paper should be referenced as such : |
| Heerema, NA |
| t(5;15)(p15;q11-13) |
| Atlas Genet Cytogenet Oncol Haematol. 1999;3(2):85-85. |
| Free journal version : [ pdf ] [ DOI ] |
| On line version : http://AtlasGeneticsOncology.org/Anomalies/t0515ID1149.html |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(5;15)(p15;q11) | |
| External links |
| Mitelman database | t(5;15)(p15;q11) [Case List] t(5;15)(p15;q11) [Transloc-MCList] |
| arrayMap (UZH-SIB Zurich) | Topo ( C42) Morph ( 9811/3) - [auto + random 100 samples .. if exist ] [tabulated segments] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Aug 12 17:00:14 CEST 2019 |
For comments and suggestions or contributions, please contact us