| Clinics and Pathology |
| Disease | B-cell, precursor ALL |
| Phenotype / cell stem origin | L1, CD10+/-, CD24+ |
| Epidemiology | 5 reported cases; Infant ALL, age 1.5-7 months at diagnosis |
| Prognosis | CR in all cases; 1 CNS relapse |
| Cytogenetics |
| Cytogenetics Morphological | t(5;15)(p15;q11-13) |
| Cytogenetics Molecular | not done |
| Additional anomalies | +14; +22 one case each |
| Variants | none reported |
| To be noted |
| Additional cases are needed to delineate the epidemiology of this rare entity: you are welcome to submit a paper to our new Case Report section. |
| Bibliography |
| Cytogenetic features of infants less than 12 months of age at diagnosis of acute lymphoblastic leukemia: impact of the 11q23 breakpoint on outcome: a report of the Childrens Cancer Group. |
| Heerema NA, Arthur DC, Sather H, Albo V, Feusner J, Lange BJ, Steinherz PG, Zeltzer P, Hammond D, Reaman GH |
| Blood. 1994 ; 83 (8) : 2274-2284. |
| PMID 8161794 |
| Contributor(s) |
| Written | 03-1999 | Nyla A. Heerema |
| Citation |
| This paper should be referenced as such : |
| Heerema NA . t(5;15)(p15;q11-13). Atlas Genet Cytogenet Oncol Haematol. March 1999 . URL : http://AtlasGeneticsOncology.org/Genes/t0515ID1149.html |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Aug 11 21:20:14 2008 |
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