Written | 1999-03 | Nyla A. Heerema |
The Ohio State University, Division of Clinical Pathology, Department of Pathology, 167 Hamilton Hall, 1645 Neil Ave, Columbus, OH 43210, USA |
Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
ICD-Morpho | 9811/3 B lymphoblastic leukaemia/lymphoma, NOS |
Atlas_Id | 1149 |
Clinics and Pathology |
Disease | B-cell, precursor ALL |
Phenotype / cell stem origin | L1, CD10+/-, CD24+ |
Epidemiology | 5 reported cases; Infant ALL, age 1.5-7 months at diagnosis |
Prognosis | CR in all cases; 1 CNS relapse |
Cytogenetics |
Cytogenetics Morphological | t(5;15)(p15;q11-13) |
Cytogenetics Molecular | not done |
Additional anomalies | +14; +22 one case each |
Variants | none reported |
To be noted |
Additional cases are needed to delineate the epidemiology of this rare entity: you are welcome to submit a paper to our new Case Report section. |
Bibliography |
Cytogenetic features of infants less than 12 months of age at diagnosis of acute lymphoblastic leukemia: impact of the 11q23 breakpoint on outcome: a report of the Childrens Cancer Group. |
Heerema NA, Arthur DC, Sather H, Albo V, Feusner J, Lange BJ, Steinherz PG, Zeltzer P, Hammond D, Reaman GH |
Blood. 1994 ; 83 (8) : 2274-2284. |
PMID 8161794 |
Citation |
This paper should be referenced as such : |
Heerema, NA |
t(5;15)(p15;q11-13) |
Atlas Genet Cytogenet Oncol Haematol. 1999;3(2):85-85. |
Free journal version : [ pdf ] [ DOI ] |
On line version : http://AtlasGeneticsOncology.org/Anomalies/t0515ID1149.html |
Translocations implicated (Data extracted from papers in the Atlas) |
t(5;15)(p15;q11) | |
External links |
Mitelman database | t(5;15)(p15;q11) |
arrayMap (UZH-SIB Zurich) | Topo ( C42) Morph ( 9811/3) - [auto + random 100 samples .. if exist ] [tabulated segments] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:25:53 CET 2020 |
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