Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA


Written2019-09Tatiana Gindina
R.M. Gorbacheva Memorial Institute of Children Oncology, Hematology and Transplantation at Pavlov First Saint-Petersburg State Medical University, Saint-Petersburg, Russian Federation / e-mail:

Abstract Review on t(6;12)(q15;p13)

Keywords Chromosome 6; Chromosome 12; t(6;12)(q15;p13); Prolymphocytic leukemia

(Note : for Links provided by Atlas : click)


ICD-Topo C420,C421,C424
ICD-Morpho 9833/3 B-cell prolymphocytic leukaemia
Atlas_Id 2046

Clinics and Pathology

Disease B-cell prolymphocytic leukemia
Epidemiology Only 5 cases to date, 3 males and 2 females, all patients were over 65 years old (Sadamori et al., 1983).
Table 1. Reported cases with t(6;12)(q15;p13).
PtsAge, genderDisease

166,MB-prolymphocytic leukemia

Prognosis No data.


Additional anomalies All five cases showed complex chromosome abnormalities. Four of the five cases were hypodiploid and displayed monosomy 17.

To be noted

Additional cases are needed to delineate the epidemiology of this rare entity:
you are welcome to submit a paper to our new Case Report section.


Possible specific chromosome change in prolymphocytic leukemia.
Sadamori N, Han T, Minowada J, Bloom ML, Henderson ES, Sandberg AA.
Blood. 1983; 19(4):729-736
PMID 6882921


This paper should be referenced as such :
Tatiana Gindina
Atlas Genet Cytogenet Oncol Haematol. 2020;24(7):-.
Free journal version : [ pdf ]   [ DOI ]
On line version :

Translocations implicated (Data extracted from papers in the Atlas)


External links

Mitelman databaset(6;12)(q15;p13)
arrayMap (UZH-SIB Zurich)Morph ( 9833/3) -   [auto + random 100 samples .. if exist ]   [tabulated segments]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Oct 8 16:36:46 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us