| Clinics and Pathology |
| Disease | Acute non lymphocytic leukemia (ANLL) (M1 and M5 ANLL) and biphenotypic leukemia |
| Epidemiology | only 3 cases available so far; 2 male and 1 female patients, aged 2, 27, and 86 yrs |
| Prognosis | unknown (one case died at 1 mth, another one is alive at 74 mths +) |
| Genetics |
| genes involved are unknown |
| Cytogenetics |
| Additional anomalies | complex karyotypes were found in two of three cases, del(5q) and +8 in two cases each, -7 in one case |
| External links |
| Other database | t(X;10)(p10;p10) | Mitelman database (CGAP - NCBI) | |
| Other database | t(X;10)(p10;p10) | CancerChromosomes (NCBI) |
| To be noted |
| Additional cases are needed to delineate the epidemiology of this rare entity: you are welcome to submit a paper to our new Case Report section. |
| Bibliography |
| Bone marrow karyotypes in 94 children with acute leukemia. |
| Heim S, Bˆ©kˆÝssy AN, Garwicz S, Heldrup J, Kristoffersson U, Mandahl N, Wiebe T, Mitelman F |
| European journal of haematology. 1990 ; 44 (4) : 227-233. |
| PMID 2344885 |
| Translocation (X;10)(p10;p10): A rare but nonrandom chromosomal abnormality in acute leukemia of myeloid differentiation. |
| Wong KF, Hayes KJ, Huh YO, Albitar M, Glassman AB |
| Cancer genetics and cytogenetics. 1996 ; 86 (2) : 153-155. |
| PMID 8603344 |
| Contributor(s) |
| Written | 07-2003 | Jean-Loup Huret |
| Citation |
| This paper should be referenced as such : |
| Huret JL . t(X;10)(p10;p10). Atlas Genet Cytogenet Oncol Haematol. July 2003 . URL : http://AtlasGeneticsOncology.org/Genes/t0X10p10p10ID1256.html |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Jul 14 16:33:31 2008 |
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