Written | 2003-07 | Jean-Loup Huret |
Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France |
Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
ICD-Morpho | 9861/3 AML with mutated NPM1; AML with mutated CEBPA; Acute myeloid leukaemia, NOS |
Atlas_Id | 1256 |
Clinics and Pathology |
Disease | Acute myeloid leukemia (AML) (M1 and M5 AML) and biphenotypic leukemia |
Epidemiology | only 3 cases available so far; 2 male and 1 female patients, aged 2, 27, and 86 yrs |
Prognosis | unknown (one case died at 1 mth, another one is alive at 74 mths +) |
Genetics |
genes involved are unknown |
Cytogenetics |
Additional anomalies | complex karyotypes were found in two of three cases, del(5q) and +8 in two cases each, -7 in one case |
To be noted |
Additional cases are needed to delineate the epidemiology of this rare entity: you are welcome to submit a paper to our new Case Report section. |
Bibliography |
Bone marrow karyotypes in 94 children with acute leukemia. |
Heim S, Békássy AN, Garwicz S, Heldrup J, Kristoffersson U, Mandahl N, Wiebe T, Mitelman F |
European journal of haematology. 1990 ; 44 (4) : 227-233. |
PMID 2344885 |
Translocation (X;10)(p10;p10): A rare but nonrandom chromosomal abnormality in acute leukemia of myeloid differentiation. |
Wong KF, Hayes KJ, Huh YO, Albitar M, Glassman AB |
Cancer genetics and cytogenetics. 1996 ; 86 (2) : 153-155. |
PMID 8603344 |
Citation |
This paper should be referenced as such : |
Huret, JL |
t(X;10)(p10;p10) |
Atlas Genet Cytogenet Oncol Haematol. 2003;7(3):187-187. |
Free journal version : [ pdf ] [ DOI ] |
On line version : http://AtlasGeneticsOncology.org/Anomalies/t0X10p10p10ID1256.html |
Translocations implicated (Data extracted from papers in the Atlas) |
t(X;10)(p10;p10) | |
External links |
Mitelman database | t(X;10)(p10;p10) |
arrayMap (UZH-SIB Zurich) | Topo ( C42) Morph ( 9861/3) - [auto + random 100 samples .. if exist ] [tabulated segments] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:26:19 CET 2020 |
For comments and suggestions or contributions, please contact us