ICD-Topo |
C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
ICD-Morpho |
9861/3 AML with mutated NPM1; AML with mutated CEBPA; Acute myeloid leukaemia, NOS
|
ICD-Morpho |
9920/3 Therapy-related myeloid neoplasms
|
ICD-Morpho |
9989/3 Myelodysplastic syndrome, unclassifiable
|
Atlas_Id |
1123 |
|  |
| |
|
t(16;21)(q24;q22) G-banding: 2 Top left - Courtesy Jean Luc Laï; 3 Bottom left - Courtesy Dorothy Hung, Luke St Heaps and Dale Wright, The Cytogenetics Department of Children's Hospital at Westmead Sydney, Australia. R-banding: Top right - Courtesy Jean Luc Laï and Bottom right - Courtesy Pascale Cornillet-Lefebvre and Stéphanie Struski). Fish studies: Top: chromosome 16 and 21 paints; Middle: RUNX1 probe: the 2 chromosomes 21 and the der(16) are labelled - Courtesy Pascale Cornillet-Lefebvre and Stéphanie Struski; Bottom: ETV6 and RUNX1 probes - Courtesy Dorothy Hung Luke St Heaps and Dale Wright, The Cytogenetics Department of Children''s Hospital at Westmead Sydney, Australia. |
| |
Secondary acute myeloblastic leukemia with t(16;21) (q24;q22). involving the AML1 gene. |
Berger R, Le Coniat M, Romana SP, Jonveaux P |
Hematology and cell therapy. 1996 ; 38 (2) : 183-186. |
PMID 8932000 |
|
The partner gene of AML1 in t(16;21) myeloid malignancies is a novel member of the MTG8(ETO) family. |
Gamou T, Kitamura E, Hosoda F, Shimizu K, Shinohara K, Hayashi Y, Nagase T, Yokoyama Y, Ohki M |
Blood. 1998 ; 91 (11) : 4028-4037. |
PMID 9596646 |
|
Metaphase fluorescence in situ hybridization (FISH) in the follow-up of 60 patients with haemopoietic malignancies. |
Nylund SJ, Ruutu T, Saarinen U, Knuutila S |
British journal of haematology. 1994 ; 88 (4) : 778-783. |
PMID 7819102 |
|
Cytogenetics of childhood acute nonlymphocytic leukemia. |
Raimondi SC, Kalwinsky DK, Hayashi Y, Behm FG, Mirro J Jr, Williams DL |
Cancer genetics and cytogenetics. 1989 ; 40 (1) : 13-27. |
PMID 2758395 |
|
AML1-MTG16 fusion gene in therapy-related acute leukemia with t(16;21)(q24;q22): two new cases. |
Salomon-Nguyen F, Busson-Le Coniat M, Lafage Pochitaloff M, Mozziconacci J, Berger R, Bernard OA |
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2000 ; 14 (9) : 1704-1705. |
PMID 10995019 |
|
A recurrent translocation, t(16;21)(q24;q22), associated with acute myelogenous leukemia: identification by fluorescence in situ hybridization. |
Shimada M, Ohtsuka E, Shimizu T, Matsumoto T, Matsushita K, Tanimoto F, Kajii T |
Cancer genetics and cytogenetics. 1997 ; 96 (2) : 102-105. |
PMID 9216714 |
|
21q22 balanced chromosome aberrations in therapy-related hematopoietic disorders: report from an international workshop. |
Slovak ML, Bedell V, Popplewell L, Arber DA, Schoch C, Slater R |
Genes, chromosomes & cancer. 2002 ; 33 (4) : 379-394. |
PMID 11921272 |
|
A case of therapy-related acute myeloblastic leukemia with t(16;21)(q24;q22) after chemotherapy with DNA-topoisomerase II inhibitors, etoposide and mitoxantrone, and the alkylating agent, cyclophosphamide. |
Takeda K, Shinohara K, Kameda N, Ariyoshi K |
International journal of hematology. 1998 ; 67 (2) : 179-186. |
PMID 9631585 |
|
Clonal karyotypic hematopoietic cell abnormalities occurring after autologous bone marrow transplantation for Hodgkin's disease and non-Hodgkin's lymphoma. |
Traweek ST, Slovak ML, Nademanee AP, Brynes RK, Niland JC, Forman SJ |
Blood. 1994 ; 84 (3) : 957-963. |
PMID 8043877 |
|