Chromosome 2

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X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ENTITIES: by Chromosome band

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Chromosome 2

[previous] 2 2p 2q 2p25 2p24 2p23 2p22 2p21 2p16 2p15 2p14 2p13 2p12 2p11 2q11 2q12 2q13 2q14 2q21 2q22 2q23 2q24 2q31 2q32 2q33 2q34 2q35 2q36 2q37 [next]

Arm 2p

chr2:0-96000000 (96000 Kb)

Chromosomal abnormalities in band 2p

(click on headers to reorder columns)

Band 1	Band 2	Class	Entity	Partner 1	Partner 2	Links	Topography	Morphology	[PubMed]	[Study]
		Mitelman	del(2p)			Mitelman (ISB-CGC)		Acute lymphoblastic leukemia/lymphoblastic lymphoma
		Mitelman	del(2p)			Mitelman (ISB-CGC)	Large intestine	Adenocarcinoma

[ Bold normal : A; Italic normal :G; Italic small : E ]

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 [previous] 2 2p 2q 2p25 2p24 2p23 2p22 2p21 2p16 2p15 2p14 2p13 2p12 2p11 2q11 2q12 2q13 2q14 2q21 2q22 2q23 2q24 2q31 2q32 2q33 2q34 2q35 2q36 2q37 [next]

References

The human genome used in these documents corresponds to the hg38 (Build GRCh38). A more precise informtion about assemby can be found at Human genome Overview.
The limits of cytogenetic bands correspond to data from UCSC : cytoBand.txt.gz

ISCN Abbreviated Terms and Symbols

[A]Atlas - Annotated genes

[G]Atlas - Other Genes

[F] fishClones (hg38)

[M] Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer [ Jan 2020 ]
and "Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer" (2012). Mitelman F, Johansson B and Mertens F (Eds.)" [Sept 2016]

[N] Mitelman Database of Chromosome Aberrations (/number)

[COS] Catalogue Of Somatic Mutations In Cancer [v90]

[COF] Catalogue Of Somatic Mutations In Cancer : Gene Fusions [v90] [PubMed 2017]

[CSV] Catalogue Of Somatic Mutations In Cancer : Structural variations (extracted frorm CosmicStructExport.tsv) [v90]) [PubMed 2014]

[CEN] Cancer Gene Census [v90]

[TF] [PubMed 2014]TCGA Fusions (MDAndersson) TCGA Fusions (Jackson Lab) [PubMed 2014] (the fusions are limited to tiers 1 and 2)

[TIC] [PubMed 2007] TicDB

[H2] [PubMed 2006] ChimerDB_2.0

[H3] [PubMed 2010] [PubMed 2017] ChimerDB_3.0 [PubMed 2017]

[K] [PubMed 2011] dbCRID

[CT] [PubMed 2011] [PubMed 2012] [PubMed 2014] ChiTARS-2.1 [PubMed 2016] ChiTARS-3.1

[LAI] [PubMed 2015] Fusion transcript loci share many genomic Features with non-fusion loci. Lai et al. BMC Genomics 2015

[PM] Gene Fusions from Pubmed abstract mining

[L] [PubMed 2011] Fusion gene microarray reveals cancer type-specificity among fusion genes. Lovf M et al.Genes Chromosomes Cancer. 2011 May;50(5):348-57.

[S] [PubMed 21009] A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. Skotheim RI, et al. Mol Cancer. 2009 Jan 19;8:5.

[V][PubMed 2012] ETV6 fusion genes in hematological malignancies: A review. De Braekeleer E. et al. Leuk Res. 2012 May 12.

[GT] [Pubmed 2015] Cell Lines (Genentech) Nature Biotech Suppl.Table8

[FC] [PubMed 2015] Fusion cancer (Beijing) (the fusions are limited to class A and B)

[NOR] [PubMed 2016] Babiceanu M et al. Recurrent chimeric fusion RNAs in non-cancer tissues and cells. Nucleic Acids Res. 2016 Feb 2 (Table S3)

[URK] [PubMed 2016] Urakami et al. Next generation sequencing approach for detecting 491 fusion genes from human cancer. Biomed Res. 2016;37(1):51-62.

[AM] [PubMed 2016] Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancersAlaei-Mahabadi B. et al.,Proc Natl Acad Sci U S A. 2016 Nov 16. pii: 201606220.

[FM] [PubMed 2018] Genomic hotspots but few recurrent fusion genes in breast cancer, Fimereli et al., Genes Chromosomes Cancer. (SupplTableS2.xls) 2018 Feb 13

[MA] [PubMed 2018] Pan-cancer genome and transcriptome analyses of1,699 paediatric leukaemias and solid tumours, Ma et al, Nature (March 2018) Table S3

[GAO] [PubMed 2018] Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Gao et al, Cell Reports (April 2018) Table S2

[MAY] [PubMed 2018] Development and Verification of an RNA Sequencing (RNA-Seq) Assay for the Detection of Gene Fusions in Tumor, Winters et al (July 2018) Table S7

[GDB] [PubMed 2019] Fusion gene annotation DataBase. Kim P t Zhou X. Nucleic Acids Res. 2019 Jan 8;47(D1):D994-D1004 [site FusionGDB]

[DDR][DDG] [PubMed 2019] Improved detection of gene fusions by applying statistical methods reveals oncogenic RNA cancer drivers, Dehghannasiri R et al, Proc Natl Acad Sci U S A. 2019 Jul 15. pii: 201900391. doi: 10.1073/pnas.1900391116

[DDR] TGCA novel recurrent fusions - Sup. Table 1

[DDG] GTEx (normal tissus) recurrent fusions - Sup. Table 1

[PC] PCAWG : Pan-cancer analysis of whole genomes. ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium. Nature. 2020 Feb;578(7793):82-93. doi: 10.1038/s41586-020-1969-6. [PubMed 2020] gene fusion data on synapse syn10003873)

Contributor(s)

Written may 2012 Philippe Dessen

Updated oct. 2021 Philippe Dessen and Jean-Loup Huret

Citation

This paper should be referenced as such :
Dessen P and Huret JL. Chromosomal band 2p. Atlas Genet Cytogenet Oncol Haematol. July 2012.
URL : http://atlasgeneticsoncology.org/Bands/2p.html

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : lun. oct. 11 15:14:17 CEST 2021

Home Genes Leukemias Solid Tumors Cancer-Prone Deep Insight Case reports Journals Portal Teaching

Written	may 2012	Philippe Dessen

Updated	oct. 2021	Philippe Dessen and Jean-Loup Huret