Chromosome 5

Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ENTITIES: by Chromosome band

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Chromosome 5

[previous] 5 5p 5q 5p15 5p14 5p13 5p12 5p11 5q11 5q12 5q13 5q14 5q15 5q21 5q22 5q23 5q31 5q32 5q33 5q34 5q35 [next]

Band 5p11

chr5:46100000-48800000 (2700 Kb)

Chromosomal abnormalities in band 5p11

Genes in band 5p11 (reference hg38)

External links

References

Chromosomal abnormalities in band 5p11

(click on headers to reorder columns)

Band 1	Band 2	Class	Entity	Links	Topography	Morphology	[PubMed]	[Study]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST115612]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST117638]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST121632]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST123945]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST127220]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST129774]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST133687]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST136205]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST137970]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST139592]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST161414]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
5p11		Cosmic_SV	del(5)(p11)	Cosmic_SV [COST27843]	large_intestine__NS	carcinoma__adenocarcinoma
		Mitelman	del(5)(p11)	Mitelman (CGAP)		Acute lymphoblastic leukemia/lymphoblastic lymphoma
		Mitelman	del(5)(p11)	Mitelman (CGAP)	Breast	Adenocarcinoma
		Mitelman	del(5)(p11)	Mitelman (CGAP)	Kidney	Adenocarcinoma
		Mitelman	del(5)(p11)	Mitelman (CGAP)		Mature B-cell neoplasm, NOS
		Mitelman	del(5)(p11)	Mitelman (CGAP)	Oral cavity	Squamous cell carcinoma
		Mitelman	del(5)(p11)	Mitelman (CGAP)	Soft tissue	Leiomyosarcoma
5p11	5q32	Cosmic_SV	del(5)(p11q32)	Cosmic_SV [COST197307]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5q35	Cosmic_SV	del(5)(p11q35)	Cosmic_SV [COST519446]	lung__NS	carcinoma__adenocarcinoma
5p13	5p11	Cosmic_SV	del(5)(p13p11)	Cosmic_SV [COST185071]	skin__NS	carcinoma__NS		[COSU656]
		Mitelman	der(15)t(5;15)(p11;p11)	Mitelman (CGAP)		Mantle cell lymphoma
		Mitelman	der(17)t(5;17)(p11;p11)	Mitelman (CGAP)		Acute myeloblastic leukemia with maturation (FAB type M2)
		Mitelman	der(17)t(5;17)(p11;p11)	Mitelman (CGAP)		Acute myeloid leukemia, NOS
		Mitelman	der(17)t(5;17)(p11;p11)	Mitelman (CGAP)		Refractory anemia with excess of blasts (FAB)
		Mitelman	der(5)t(5;13)(p11;q14)	Mitelman (CGAP)	Skeleton	Osteosarcoma, NOS
5p11		Cosmic_SV	dup(5)(p11)	Cosmic_SV [COST196842]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	dup(5)(p11p11)	Cosmic_SV [COST119157]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
5p11	5p11	Cosmic_SV	dup(5)(p11p11)	Cosmic_SV [COST159576]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
5p11	5p11	Cosmic_SV	dup(5)(p11p11)	Cosmic_SV [COST193851]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
5p11	5p11	Cosmic_SV	inv(5)(p11p11)	Cosmic_SV [COST148211]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
5p12	5p12	Cosmic_SV	inv(5)(p12p12)	Cosmic_SV [COST156435]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
1p21	5p11	dbCRID	t(1;5)(p21;p11)	11072		Myeloid Hematological Malignancies	[PubMed]
		Mitelman	t(5;13)(p11;q14)	Mitelman (CGAP)	Skeleton	Osteosarcoma, NOS
		Mitelman	t(5;15)(p11;p11)	Mitelman (CGAP)		Mantle cell lymphoma
		Mitelman	t(5;17)(p11;p11)	Mitelman (CGAP)		Acute myeloblastic leukemia with maturation (FAB type M2)
		Mitelman	t(5;17)(p11;p11)	Mitelman (CGAP)		Acute myeloid leukemia, NOS
		Mitelman	t(5;17)(p11;p11)	Mitelman (CGAP)		Refractory anemia with excess of blasts (FAB)
5p11	17q11	Atlas - Leukemia	t(5;17)(p11;q11)	t0517p11q11ID1772		AML	[Biblio]
1p31	5p11	Cosmic_SV	u(1;5)(p31;p11)	Cosmic_SV [COST124777]	pancreas__NS	carcinoma__ductal_carcinoma		[COSU328]
1q41	5p11	Cosmic_SV	u(1;5)(q41;p11)	Cosmic_SV [COST451101]	breast__NS	carcinoma__HER-positive_carcinoma		[COSU668]
18p11	5p11	Cosmic_SV	u(18;5)(p11;p11)	Cosmic_SV [COST137931]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
20p11	5p11	Cosmic_SV	u(20;5)(p11;p11)	Cosmic_SV [COST167422]	central_nervous_system__brain	primitive_neuroectodermal_tumour-medulloblastoma__large_cell		[COSU379]
5p11	10q22	Cosmic_SV	u(5;10)(p11;q22)	Cosmic_SV [COST445844]	breast__NS	carcinoma__HER-positive_carcinoma		[COSU668]
5p11	11q24	Cosmic_SV	u(5;11)(p11;q24)	Cosmic_SV [COST162632]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
5p11	17p13	Cosmic_SV	u(5;17)(p11;p13)	Cosmic_SV [COST327863]	breast__NS	carcinoma__ductal_carcinoma		[COSU652]
5p11	3q21	Cosmic_SV	u(5;3)(p11;q21)	Cosmic_SV [COST185820]	skin__NS	carcinoma__NS		[COSU656]
5p11	6p25	Cosmic_SV	u(5;6)(p11;p25)	Cosmic_SV [COST136780]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
5p11	6p25	Cosmic_SV	u(5;6)(p11;p25)	Cosmic_SV [COST449315]	breast__NS	carcinoma__HER-positive_carcinoma		[COSU668]
5p11	6q11	Cosmic_SV	u(5;6)(p11;q11)	Cosmic_SV [COST441842]	breast__NS	carcinoma__HER-positive_carcinoma		[COSU668]
5p11	6q24	Cosmic_SV	u(5;6)(p11;q24)	Cosmic_SV [COST447353]	breast__NS	carcinoma__HER-positive_carcinoma		[COSU668]
5p11	9p21	Cosmic_SV	u(5;9)(p11;p21)	Cosmic_SV [COST137585]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
5p11	9p24	Cosmic_SV	u(5;9)(p11;p24)	Cosmic_SV [COST465607]	breast__NS	carcinoma__HER-positive_carcinoma		[COSU668]
		Cosmic_SV	u(5;)(p11;)	Cosmic_SV [COST518142]	lung__NS	carcinoma__adenocarcinoma
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST113520]	haematopoietic_and_lymphoid_tissue__NS	lymphoid_neoplasm__NS		[COSU440]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST114096]	haematopoietic_and_lymphoid_tissue__NS	lymphoid_neoplasm__NS		[COSU440]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST114201]	haematopoietic_and_lymphoid_tissue__NS	lymphoid_neoplasm__NS		[COSU440]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST194589]	bone__NS	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour__NS		[COSU645]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST453466]	breast__NS	carcinoma__HER-positive_carcinoma		[COSU668]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST461337]	breast__NS	carcinoma__HER-positive_carcinoma		[COSU668]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST492243]	prostate__NS	carcinoma__adenocarcinoma		[COSU675]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST554103]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST558733]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST559073]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST560000]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST561276]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST571639]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST578269]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST579040]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST581554]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST581696]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST721789]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST722975]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST723701]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST725514]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST732316]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST736821]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST741185]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST742731]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST742740]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST757621]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST760787]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p11	Cosmic_SV	u(5)(p11;p11)	Cosmic_SV [COST766150]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p15	Cosmic_SV	u(5)(p11;p15)	Cosmic_SV [COST739132]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5p15	Cosmic_SV	u(5)(p11;p15)	Cosmic_SV [COST757673]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5q21	Cosmic_SV	u(5)(p11;q21)	Cosmic_SV [COST568314]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5q21	Cosmic_SV	u(5)(p11;q21)	Cosmic_SV [COST727262]	prostate__NS	carcinoma__adenocarcinoma		[COSU537]
5p11	5q33	Cosmic_SV	u(5)(p11;q33)	Cosmic_SV [COST494736]	endometrium__NS	carcinoma__carcinosarcoma-malignant_mesodermal_mixed_tumour		[COSU677]
5p12	5p11	Cosmic_SV	u(5)(p12;p11)	Cosmic_SV [COST461774]	breast__NS	carcinoma__HER-positive_carcinoma		[COSU668]
5p15	5p11	Cosmic_SV	u(5)(p15;p11)	Cosmic_SV [COST327845]	breast__NS	carcinoma__ductal_carcinoma		[COSU652]
5p15	5p11	Cosmic_SV	u(5)(p15;p11)	Cosmic_SV [COST749838]	prostate__NS	carcinoma__adenocarcinoma		[COSU538]
6p25	5p11	Cosmic_SV	u(6;5)(p25;p11)	Cosmic_SV [COST153477]	ovary__NS	carcinoma__mixed_adenosquamous_carcinoma		[COSU585]
7p21	5p11	Cosmic_SV	u(7;5)(p21;p11)	Cosmic_SV [COST185559]	skin__NS	carcinoma__NS		[COSU656]

Genes in band 5p11

(click on headers to reorder columns)

GoldenPath hg38	Band 1	Band 2	Class	Clone	Fusion	Partner 1	Partner 2	Links	Topography	Morphology	Pubmed	Omim	Accession

[ Bold normal : A; Italic normal :G; Italic small : E ]

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 [previous] 5 5p 5q 5p15 5p14 5p13 5p12 5p11 5q11 5q12 5q13 5q14 5q15 5q21 5q22 5q23 5q31 5q32 5q33 5q34 5q35 [next]

External links

Mitelman Database [NCI] : Breakpoint 5p11

[ UCSC ][ enSembl ][ MapView - NCBI ][ 1000Genomes ][ EVS ][ CGWB ][ DGV ][ DBVar ][ OMIM ][ HapMap ][ DECIPHER ] [ ECARUCA ]
Gene Expression (MSigDB) in 5p11 [ HTC ] [ NCI ] [ INV ]

Global tables

Anomalies list (tabulated txt file)

Genes list (tabulated txt file)

Anomalies list - limited to abnormalities with gene fusions(tabulated txt file)

Genes list - limited to genes fusions (tabulated txt file)

list of gene fusions for each gene (with origins of the data)

list of gene fusions by origin (with topography and morphology)

The human genome used in these documents corresponds to the hg38 (Build GRCh38). A more precise informtion about assemby can be found at Human genome Overview.
The limits of cytogenetic bands correspond to data from UCSC : cytoBand.txt.gz

ISCN Abbreviated Terms and Symbols [NCI]

[A]Atlas - Annotated genes

[G]Atlas - Other Genes

[F] fishClones (hg38)

[M] Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer [ CGAP Jul 2019]
and "Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer" (2012). Mitelman F, Johansson B and Mertens F (Eds.)" [Sept 2016]

[N] Mitelman Database of Chromosome Aberrations (/number)

[COS] Catalogue Of Somatic Mutations In Cancer [v89]

[COF] Catalogue Of Somatic Mutations In Cancer : Gene Fusions [v89] [PubMed 2017]

[CSV] Catalogue Of Somatic Mutations In Cancer : Structural variations (extracted frorm CosmicStructExport.tsv) [v89]) [PubMed 2014]

[CEN] Cancer Gene Census [v89]

[TF] [PubMed 2014]TCGA Fusions (MDAndersson) TCGA Fusions (Jackson Lab) [PubMed 2014] (the fusions are limited to tiers 1 and 2)

[TIC] [PubMed 2007] TicDB

[H2] [PubMed 2006] ChimerDB_2.0

[H3] [PubMed 2010] [PubMed 2017] ChimerDB_3.0 [PubMed 2017]

[K] [PubMed 2011] dbCRID

[CT] [PubMed 2011] [PubMed 2012] [PubMed 2014] ChiTARS-2.1

[PubMed 2016] ChiTARS-3.1

[LAI] [PubMed 2015] Fusion transcript loci share many genomic Features with non-fusion loci. Lai et al. BMC Genomics 2015

[PM] Gene Fusions from Pubmed abstract mining

[L] [PubMed 2011] Fusion gene microarray reveals cancer type-specificity among fusion genes. Lovf M et al.Genes Chromosomes Cancer. 2011 May;50(5):348-57.

[S] [PubMed 21009] A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. Skotheim RI, et al. Mol Cancer. 2009 Jan 19;8:5.

[V][PubMed 2012]

ETV6 fusion genes in hematological malignancies: A review. De Braekeleer E. et al. Leuk Res. 2012 May 12.

[GT] [Pubmed 2015] Cell Lines (Genentech) Nature Biotech Suppl.Table8

[FC] [PubMed 2015] Fusion cancer (Beijing) (the fusions are limited to class A and B)

[NOR] [PubMed 2016] Babiceanu M et al. Recurrent chimeric fusion RNAs in non-cancer tissues and cells. Nucleic Acids Res. 2016 Feb 2 (Table S3)

[URK] [PubMed 2016] Urakami et al. Next generation sequencing approach for detecting 491 fusion genes from human cancer. Biomed Res. 2016;37(1):51-62.

[AM] [PubMed 2016] Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancersAlaei-Mahabadi B. et al.,Proc Natl Acad Sci U S A. 2016 Nov 16. pii: 201606220.

[FM] [PubMed 2018] Genomic hotspots but few recurrent fusion genes in breast cancer, Fimereli et al., Genes Chromosomes Cancer. (SupplTableS2.xls) 2018 Feb 13

[MA] [PubMed 2018] Pan-cancer genome and transcriptome analyses of1,699 paediatric leukaemias and solid tumours, Ma et al, Nature (March 2018) Table S3

[GAO] [PubMed 2018] Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Gao et al, Cell Reports (April 2018) Table S2

[MAY] [PubMed 2018] Development and Verification of an RNA Sequencing (RNA-Seq) Assay for the Detection of Gene Fusions in Tumor, Winters et al (July 2018) Table S7

[GDB] [PubMed 2019] Fusion gene annotation DataBase. Kim P t Zhou X. Nucleic Acids Res. 2019 Jan 8;47(D1):D994-D1004 [site FusionGDB]

[DDR][DDG] [PubMed 2019] Improved detection of gene fusions by applying statistical methods reveals oncogenic RNA cancer drivers, Dehghannasiri R et al, Proc Natl Acad Sci U S A. 2019 Jul 15. pii: 201900391. doi: 10.1073/pnas.1900391116

[DDR] TGCA novel recurrent fusions - Sup. Table 1

[DDG] GTEx (normal tissus) recurrent fusions - Sup. Table 1

Contributor(s)

Written may 2012 Philippe Dessen

Updated août 2019 Philippe Dessen and Jean-Loup Huret

Citation

This paper should be referenced as such :
Dessen P and Huret JL. Chromosomal band 5p11. Atlas Genet Cytogenet Oncol Haematol. July 2012.
URL : http://atlasgeneticsoncology.org/Bands/5p11.html

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : mar. août 6 14:23:04 CEST 2019

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Written	may 2012	Philippe Dessen

Updated	août 2019	Philippe Dessen and Jean-Loup Huret