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Understanding the structure and function of ASH2L
Chromothripsis: a new molecular mechanism in cancer development
Genes
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ASH2L (ash2 (absent, small, or homeotic)-like (Drosophila))
ATR (ataxia telangiectasia and Rad3 related)
BRCA2 (breast cancer 2, early onset)
BRD4 (bromodomain containing 4)
CDA (Cytidine Deaminase)
CDT1 (chromatin licensing and DNA replication factor 1)
CLSPN (claspin)
DNAJA3 (DnaJ (Hsp40) homolog, subfamily A, member 3)
E2F4 (E2F transcription factor 4, p107/p130-binding)
EWSR1 (Ewing sarcoma breakpoint region 1)
FANCA (Fanconi anemia, complementation group A)
FEN1 (flap structure-specific endonuclease 1)
FOXF1 (forkhead box F1)
GSK3B (glycogen synthase kinase 3 beta)
HUS1 (HUS1 checkpoint homolog (S. pombe))
ID1 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein)
MCM5 (minichromosome maintenance complex component 5)
MIR146B (microRNA 146b)
MIR449A (microRNA 449a)
PCNA (proliferating cell nuclear antigen)
RAD51D (RAD51-like 3 (S. cerevisiae))
RAD9A (RAD9 homolog A (S. pombe))
RAN (RAN, member RAS oncogene family)
REST (RE1-silencing transcription factor)
RPA2 (replication protein A2, 32kDa)
SIRT1 (sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae))
SOX2 (SRY (sex determining region Y)-box 2)
TERF2 (telomeric repeat binding factor 2)
TNKS (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase)
TYMP (thymidine phosphorylase)
UBD (ubiquitin D)
WRN (Werner syndrome, RecQ helicase-like)
XRCC6 (X-ray repair complementing defective repair in Chinese hamster cells 6)
Figure from BRCA2
Figure from CDT1
Figure from E2F4
Figure from EWSR1
Figure from FANCA
Figure from FANCA
Figure from FEN1
Figure from FEN1
Figure from GSK3B
Figure from HUS1
Figure from MIR146B
Figure from PCNA
Figure from RAD51
Figure from REST
Figure from RPA2
Figure from TNKS
Figure from XRCC6