DNA replication-recombination

Deep Insight Understanding the structure and function of ASH2L Mechanisms of chromosomal instability and carcinogenesis Chromothripsis: a new molecular mechanism in cancer development Genes AFAP1L2 (actin filament associated protein 1-like 2) ASH2L (ash2 (absent, small, or homeotic)-like (Drosophila)) ATR (ataxia telangiectasia and Rad3 related) AURKB (aurora kinase B) BRCA2 (breast cancer 2, early onset) BRD4 (bromodomain containing 4) CDA (Cytidine Deaminase) CDT1 (chromatin licensing and DNA replication factor 1) CENPW (centromere protein W) CHD6 (chromodomain helicase DNA binding protein 6) CLSPN (claspin) DHFR (dihydrofolate reductase) DNAJA3 (DnaJ (Hsp40) homolog, subfamily A, member 3) E2F4 (E2F transcription factor 4, p107/p130-binding) EWSR1 (Ewing sarcoma breakpoint region 1) FANCA (Fanconi anemia, complementation group A) FANCB (FA complementation group B) FANCL (FA complementation group L) FBXO11 (F-box protein 11) FEN1 (flap structure-specific endonuclease 1) FOXF1 (forkhead box F1) GSK3B (glycogen synthase kinase 3 beta) HELLS (Helicase, Lymphoid-Specific) HUS1 (HUS1 checkpoint homolog (S. pombe)) ID1 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein) MCM5 (minichromosome maintenance complex component 5) MIR146B (microRNA 146b) MIR449A (microRNA 449a) PALB2 (partner and localizer of BRCA2) PARP1 (poly(ADP-ribose) polymerase 1) PCNA (proliferating cell nuclear antigen) PIM1 (pim-1 oncogene) PML (promyelocytic leukemia) POLD1 (DNA polymerase delta 1, catalytic subunit) POLE (DNA polymerase epsilon, catalytic subunit) PPP2R1A (protein phosphatase 2 regulatory subunit A, alpha) RAD51D (RAD51-like 3 (S. cerevisiae)) RAD52 (RAD52 homolog (S. cerevisiae)) RAD9A (RAD9 homolog A (S. pombe)) RANBP2 (RAN binding protein 2) RAN (RAN, member RAS oncogene family) RAN (RAN, member RAS oncogene family) REST (RE1-silencing transcription factor) RPA2 (replication protein A2, 32kDa) S100A4 (S100 Calcium Binding Protein A4) SIRT1 (sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)) SOX2 (SRY (sex determining region Y)-box 2) TERF2 (telomeric repeat binding factor 2) TNKS (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase) TYMP (thymidine phosphorylase) UBD (ubiquitin D) WRN (Werner syndrome, RecQ helicase-like) XRCC2 (X-ray repair cross complementing 2) XRCC6 (X-ray repair complementing defective repair in Chinese hamster cells 6)

Iconography Figure from Mechanisms_of_chromosomal_instability_and_carcinogenesis Figure from Mechanisms_of_chromosomal_instability_and_carcinogenesis Figure from Mechanisms_of_chromosomal_instability_and_carcinogenesis Figure from AFAP1L2 Figure from AURKB Figure from AURKB Figure from AURKB Figure from BRCA2 Figure from CDT1 Figure from CENPW Figure from CHD6 Figure from E2F4 Figure from EWSR1 Figure from FANCA Figure from FANCA Figure from FBXO11 Figure from FEN1 Figure from FEN1 Figure from GSK3B Figure from HELLS Figure from HUS1 Figure from MIR146B Figure from PCNA Figure from RAD51 Figure from RAD52 Figure from RAD52 Figure from RAD52 Figure from RANBP2 Figure from RANBP2 Figure from REST Figure from RPA2 Figure from TNKS Figure from XRCC6

Contributor(s)

Written	Oct 2009	Jean-Loup Huret
Updated	Jan 2020	Jean-Loup Huret and Philippe Dessen

Citation

This paper should be referenced as such :

, Huret JL, Dessen P.. DNA_replication-recombination. Atlas Genet Cytogenet Oncol Haematol. Jan 2020 . URL : http://AtlasGeneticsOncology.org/Categories/DNA_replication-recombination.html