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JAK-STAT

Deep Insight

Th17 cells: inflammation and regulation
Intracellular tyrosine phosphatases and kinases in lymphoma

Genes

ANP32A (acidic (leucine-rich) nuclear phosphoprotein 32 family, member A)
BCL6 (B-Cell Lymphoma 6)
BRWD3 (bromodomain and WD repeat domain containing 3)
CXCL10 (chemokine (C-X-C motif) ligand 10)
CXCL12 (chemokine (C-X-C motif) ligand 12)
DDR1 (discoidin domain receptor tyrosine kinase 1)
DIRAS3 (DIRAS family, GTP-binding RAS-like 3)
DNAJA3 (DnaJ (Hsp40) homolog, subfamily A, member 3)
EIF2AK2 (eukaryotic translation initiation factor 2-alpha kinase 2)
FGFR4 (fibroblast growth factor receptor 4)
FLCN (folliculin gene)
GFI1 (growth factor independent 1 transcription repressor)
GPRC5A (G protein-coupled receptor, family C, group 5, member A)
HSPB8 (heat shock 22kDa protein 8)
IL22 (interleukin 22)
IL22RA1 (interleukin 22 receptor, alpha 1)
IL23A (interleukin 23, alpha subunit p19)
IL7R (interleukin 7 receptor)
IRS2 (insulin receptor substrate 2)
JAK1 (Janus kinase 1)
LIFR (leukemia inhibitory factor receptor alpha)
MIR200C (microRNA 200c)
MST1 (macrophage stimulating 1 (hepatocyte growth factor-like))
NDUFA13 (NADH:ubiquinone oxidoreductase subunit A13)
NGFR (nerve growth factor receptor)
NR3C1 (nuclear receptor subfamily 3, group C, member 1/glucocorticoid receptor)
PIAS1 (protein inhibitor of activated STAT, 1)
PLCG1 (Phospholipase C, Gamma 1)
PML (promyelocytic leukemia)
PRLR (prolactin receptor)
PTHLH (parathyroid hormone-like hormone)
RHOA (ras homolog gene family, member A)
ROS1 (ROS proto-oncogene 1 , receptor tyrosine kinase)
S100A4 (S100 Calcium Binding Protein A4)
S100A7 (S100 calcium binding protein A7)
S100A8 (S100 calcium binding protein A8)
S100A9 (S100 calcium binding protein A9)
SASH1 (SAM and SH3 domain containing 1)
SGK1 (serum/glucocorticoid regulated kinase 1)
SIRT1 (sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae))
SOCS1 (Suppressor of cytokine signaling 1)
SOCS2 (suppressor of cytokine signaling 2)
SOCS3 (suppressor of cytokine signaling 3)
STAT2 (Signal Transducer and Activator of Transcription 2)
STAT5B (signal transducer and activator of transcription 5B)
SULF2 (sulfatase 2)
THRB (Thyroid Hormone Receptor, Beta)
VAV3 (vav 3 guanine nucleotide exchange factor)

Iconography


Figure from BCL6


Figure from BCL6


Figure from BRWD3


Figure from DDR1


Figure from DIRAS3


Figure from EIF2AK2


Figure from FGFR4


Figure from GFI1


Figure from HSPB8


Figure from HSPB8


Figure from IL22RA1


Figure from IL22RA1


Figure from IL23A


Figure from LIFR


Figure from MST1


Figure from NGFR


Figure from NR3C1


Figure from PIAS1


Figure from PLCG1


Figure from PRKCD


Figure from PRKCD


Figure from PRKCD


Figure from S100A7


Figure from S100A9


Figure from SASH1


Figure from SGK1


Figure from STAT2


Figure from STAT5B


Figure from VAV3


Figure from CXCL12


Figure from NDUFA13

Contributor(s)

WrittenOct 2009Jean-Loup Huret
UpdatedAug 2017Jean-Loup Huret and Philippe Dessen

Citation

This paper should be referenced as such :
, Huret JL, Dessen P.. JAK-STAT. Atlas Genet Cytogenet Oncol Haematol. Aug 2017 .
URL : http://AtlasGeneticsOncology.org/Categories/JAK-STAT.html


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 14 13:46:10 CEST 2017

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