Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Deep Insight

Adiponectin and cancer
Mechanisms and regulation of autophagy in mammalian cells
The IKK-related kinases, unsuspected culprits in oncogenesis?
Upstream Signal Transduction of NF-kB Activation


AAMP (angio-associated, migratory cell protein)
DAB2IP (DAB2 interacting protein)
AGER (advanced glycosylation end product-specific receptor)
ATF3 (activating transcription factor 3)
BAG3 (Bcl-2 associated athanogene 3)
BCL6 (B-Cell Lymphoma 6)
BEX1 (brain expressed, X-linked 1)
BEX2 (brain expressed X-linked 2)
BRMS1 (breast cancer metastasis suppressor 1)
BTRC (beta-transducin repeat containing)
CARD10 (caspase recruitment domain family, member 10)
CARD8 (caspase recruitment domain family, member 8)
CASP8AP2 (caspase 8 associated protein 2)
CASP8 (Caspase 8, Apoptosis-Related Cysteine Peptidase)
CD59 (CD59 molecule, complement regulatory protein)
CD74 (CD74 molecule, major histocompatibility complex, class II invariant chain)
CD82 (CD82 molecule)
COPS2 (COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis))
CXCL10 (chemokine (C-X-C motif) ligand 10)
CXCL12 (chemokine (C-X-C motif) ligand 12)
CXCR1 (chemokine (C-X-C motif) receptor 1)
CXXC5 (CXXC finger protein 5)
CYLD (cylindromatosis (turban tumor syndrome))
DDR1 (discoidin domain receptor tyrosine kinase 1)
DGKA (diacylglycerol kinase, alpha 80kDa)
DIABLO (diablo, IAP-binding mitochondrial protein)
DMBT1 (Deleted in malignant brain tumors 1)
DNAJA3 (DnaJ (Hsp40) homolog, subfamily A, member 3)
DPP4 (dipeptidyl-peptidase 4)
DUSP10 (dual specificity phosphatase 10)
E2F4 (E2F transcription factor 4, p107/p130-binding)
EEF2K (eukaryotic elongation factor 2 kinase)
EIF2AK2 (eukaryotic translation initiation factor 2-alpha kinase 2)
ERC1 (ELKS/RAB6-interacting/CAST family member 1)
ERRFI1 (ERBB receptor feedback inhibitor 1)
FAS (Fas cell surface death receptor)
FKBP5 (FK506 binding protein 5)
FPR1 (formyl peptide receptor 1)
GADD45A (growth arrest and DNA-damage-inducible, alpha)
GFI1 (growth factor independent 1 transcription repressor)
GPRC5A (G protein-coupled receptor, family C, group 5, member A)
GSK3B (glycogen synthase kinase 3 beta)
IER3 (immediate early response 3)
IL23A (interleukin 23, alpha subunit p19)
ILK (integrin-linked kinase)
ING4 (inhibitor of growth family, member 4)
ITGA6 (integrin, alpha 6)
PCLAF (PCNA clamp associated factor)
LDOC1 (leucine zipper, down-regulated in cancer 1)
LIMD1 (LIM domains containing 1)
LPAR2 (lysophosphatidic acid receptor 2)
MACROD1 (MACRO domain containing 1)
MCC (mutated in colorectal cancers)
MIR146B (microRNA 146b)
MIR200C (microRNA 200c)
MST1 (macrophage stimulating 1 (hepatocyte growth factor-like))
NCOA1 (Nuclear receptor coactivator 1)
NFKB1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 1)
NGFR (nerve growth factor receptor)
NKX2-3 (NK2 homeobox 3)
NR3C1 (nuclear receptor subfamily 3, group C, member 1/glucocorticoid receptor)
NT5E (5'-nucleotidase, ecto (CD73))
OLFM4 (olfactomedin 4)
PARP1 (poly(ADP-ribose) polymerase 1)
PAWR (PRKC apoptosis WT1 regulator protein; Prostate apoptosis response-4, Par-4)
PEBP1 (phosphatidylethanolamine binding protein 1)
PEG3 (paternally expressed 3)
PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha)
PLA2G2A (phospholipase A2, group IIA (platelets, synovial fluid))
PML (promyelocytic leukemia)
PRDX4 (peroxiredoxin 4)
PRKCI (protein kinase C, iota)
PYCARD (PYD and CARD domain containing)
RACGAP1 (Rac GTPase activating protein 1)
RELB (v-rel reticuloendotheliosis viral oncogene homolog B)
REL v-rel reticuloendotheliosis viral oncogene homolog (avian)
RHOA (ras homolog gene family, member A)
RLN2 (relaxin 2)
RNF11 (ring finger protein 11)
S100A4 (S100 Calcium Binding Protein A4)
S100A7 (S100 calcium binding protein A7)
S100A8 (S100 calcium binding protein A8)
S100A9 (S100 calcium binding protein A9)
SGK1 (serum/glucocorticoid regulated kinase 1)
SIAH2 (seven in absentia homolog 2 (Drosophila))
SIRT1 (sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae))
SIVA1 (SIVA1, Apoptosis-Inducing Factor)
SLPI (secretory leukocyte peptidase inhibitor)
SOCS2 (suppressor of cytokine signaling 2)
SPRY1 (Sprouty Homolog 1, Antagonist Of FGF Signaling (Drosophila))
SYK (spleen tyrosine kinase)
TCL1A (T-cell leukemia/lymphoma 1A)
TFG (TRK-fused gene)
TGFBR3 (transforming growth factor, beta receptor III)
TGM2 (transglutaminase 2)
THRB (Thyroid Hormone Receptor, Beta)
TNFRSF17 (tumor necrosis factor receptor superfamily, member 17)
TNFSF15 (tumor necrosis factor (ligand) superfamily, member 15)
TPH1 (tryptophan hydroxylase 1)
TRAF4 (TNF receptor-associated factor 4)
TRIM27 (tripartite motif containing 27)
TYMP (thymidine phosphorylase)
UBD (ubiquitin D)
USP15 (ubiquitin specific peptidase 15)
VAV3 (vav 3 guanine nucleotide exchange factor)
WAS (Wiskott-Aldrich syndrome)
WWTR1 (WW domain containing transcription regulator 1)
ZAP70 (zeta-chain (TCR) associated protein kinase 70kDa)


Figure from IKK

Figure from IKK

Figure from IKK

Figure from IKK

Figure from NFKB

Figure from NFKB

Figure from NFKB

Figure from AAMP

Figure from AGER

Figure from ATF3

Figure from BCL6

Figure from BCL6

Figure from BRMS1

Figure from BTRC

Figure from CARD10

Figure from CARD8

Figure from CD74

Figure from COPS2

Figure from CXCL12

Figure from CXCR1

Figure from CXXC5

Figure from CYLD

Figure from DGKA

Figure from DPP4

Figure from E2F4

Figure from EIF2AK2

Figure from ERRFI1

Figure from FAS

Figure from FAS

Figure from FGFR1

Figure from FPR1

Figure from GFI1

Figure from GSK3B

Figure from IER3

Figure from IL17A

Figure from IL23A

Figure from ILK

Figure from ILK

Figure from ING4

Figure from LIMD1

Figure from LPAR2

Figure from MIR146B

Figure from MST1

Figure from NFKB1

Figure from NGFR

Figure from NKX2-3

Figure from NR3C1

Figure from PRKCI

Figure from RNF11

Figure from RNF11

Figure from SGK1

Figure from SIAH2

Figure from TGFBR3

Figure from TRIM27

Figure from USP15

Figure from VAV3

Figure from WWTR1

Figure from ZAP70


WrittenOct 2009Jean-Loup Huret
UpdatedJan 2021Jean-Loup Huret and Philippe Dessen


This paper should be referenced as such :
, Huret JL, Dessen P.. NF-kB. Atlas Genet Cytogenet Oncol Haematol. Jan 2021 .

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jan 13 17:37:04 CET 2021

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