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NF-kB

Deep Insight

Adiponectin and cancer
Mechanisms and regulation of autophagy in mammalian cells
The IKK-related kinases, unsuspected culprits in oncogenesis?
Upstream Signal Transduction of NF-kB Activation

Genes

AAMP (angio-associated, migratory cell protein)
DAB2IP (DAB2 interacting protein)
AGER (advanced glycosylation end product-specific receptor)
ATF3 (activating transcription factor 3)
BAG3 (Bcl-2 associated athanogene 3)
BCL6 (B-Cell Lymphoma 6)
BEX1 (brain expressed, X-linked 1)
BEX2 (brain expressed X-linked 2)
BRMS1 (breast cancer metastasis suppressor 1)
BTRC (beta-transducin repeat containing)
CARD10 (caspase recruitment domain family, member 10)
CARD8 (caspase recruitment domain family, member 8)
CASP8AP2 (caspase 8 associated protein 2)
CASP8 (Caspase 8, Apoptosis-Related Cysteine Peptidase)
CD59 (CD59 molecule, complement regulatory protein)
CD74 (CD74 molecule, major histocompatibility complex, class II invariant chain)
CD82 (CD82 molecule)
COPS2 (COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis))
CXCL10 (chemokine (C-X-C motif) ligand 10)
CXCL12 (chemokine (C-X-C motif) ligand 12)
CXCR1 (chemokine (C-X-C motif) receptor 1)
CXXC5 (CXXC finger protein 5)
CYLD (cylindromatosis (turban tumor syndrome))
DDR1 (discoidin domain receptor tyrosine kinase 1)
DGKA (diacylglycerol kinase, alpha 80kDa)
DIABLO (diablo, IAP-binding mitochondrial protein)
DMBT1 (Deleted in malignant brain tumors 1)
DNAJA3 (DnaJ (Hsp40) homolog, subfamily A, member 3)
DPP4 (dipeptidyl-peptidase 4)
DUSP10 (dual specificity phosphatase 10)
E2F4 (E2F transcription factor 4, p107/p130-binding)
EEF2K (eukaryotic elongation factor 2 kinase)
EIF2AK2 (eukaryotic translation initiation factor 2-alpha kinase 2)
ERC1 (ELKS/RAB6-interacting/CAST family member 1)
ERRFI1 (ERBB receptor feedback inhibitor 1)
FAS (Fas cell surface death receptor)
FKBP5 (FK506 binding protein 5)
FPR1 (formyl peptide receptor 1)
GADD45A (growth arrest and DNA-damage-inducible, alpha)
GFI1 (growth factor independent 1 transcription repressor)
GPRC5A (G protein-coupled receptor, family C, group 5, member A)
GSK3B (glycogen synthase kinase 3 beta)
IER3 (immediate early response 3)
IL23A (interleukin 23, alpha subunit p19)
ILK (integrin-linked kinase)
ING4 (inhibitor of growth family, member 4)
ITGA6 (integrin, alpha 6)
PCLAF (PCNA clamp associated factor)
LDOC1 (leucine zipper, down-regulated in cancer 1)
LIMD1 (LIM domains containing 1)
LPAR2 (lysophosphatidic acid receptor 2)
MACROD1 (MACRO domain containing 1)
MCC (mutated in colorectal cancers)
MIR146B (microRNA 146b)
MIR200C (microRNA 200c)
MST1 (macrophage stimulating 1 (hepatocyte growth factor-like))
NFKB1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 1)
NGFR (nerve growth factor receptor)
NKX2-3 (NK2 homeobox 3)
NR3C1 (nuclear receptor subfamily 3, group C, member 1/glucocorticoid receptor)
NT5E (5'-nucleotidase, ecto (CD73))
OLFM4 (olfactomedin 4)
PAWR (PRKC apoptosis WT1 regulator protein; Prostate apoptosis response-4, Par-4)
PEBP1 (phosphatidylethanolamine binding protein 1)
PEG3 (paternally expressed 3)
PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha)
PLA2G2A (phospholipase A2, group IIA (platelets, synovial fluid))
PML (promyelocytic leukemia)
PRDX4 (peroxiredoxin 4)
PRKCI (protein kinase C, iota)
PYCARD (PYD and CARD domain containing)
RACGAP1 (Rac GTPase activating protein 1)
RELB (v-rel reticuloendotheliosis viral oncogene homolog B)
REL v-rel reticuloendotheliosis viral oncogene homolog (avian)
RHOA (ras homolog gene family, member A)
RLN2 (relaxin 2)
RNF11 (ring finger protein 11)
S100A4 (S100 Calcium Binding Protein A4)
S100A7 (S100 calcium binding protein A7)
S100A8 (S100 calcium binding protein A8)
S100A9 (S100 calcium binding protein A9)
SGK1 (serum/glucocorticoid regulated kinase 1)
SIAH2 (seven in absentia homolog 2 (Drosophila))
SIRT1 (sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae))
SIVA1 (SIVA1, Apoptosis-Inducing Factor)
SLPI (secretory leukocyte peptidase inhibitor)
SOCS2 (suppressor of cytokine signaling 2)
SPRY1 (Sprouty Homolog 1, Antagonist Of FGF Signaling (Drosophila))
SYK (spleen tyrosine kinase)
TCL1A (T-cell leukemia/lymphoma 1A)
TFG (TRK-fused gene)
TGFBR3 (transforming growth factor, beta receptor III)
TGM2 (transglutaminase 2)
THRB (Thyroid Hormone Receptor, Beta)
TNFRSF17 (tumor necrosis factor receptor superfamily, member 17)
TNFSF15 (tumor necrosis factor (ligand) superfamily, member 15)
TRAF4 (TNF receptor-associated factor 4)
TRIM27 (tripartite motif containing 27)
TYMP (thymidine phosphorylase)
UBD (ubiquitin D)
USP15 (ubiquitin specific peptidase 15)
VAV3 (vav 3 guanine nucleotide exchange factor)
WAS (Wiskott-Aldrich syndrome)
WWTR1 (WW domain containing transcription regulator 1)
ZAP70 (zeta-chain (TCR) associated protein kinase 70kDa)

Iconography


Figure from IKK


Figure from IKK


Figure from IKK


Figure from IKK


Figure from NFKB


Figure from NFKB


Figure from NFKB


Figure from AAMP


Figure from AGER


Figure from ATF3


Figure from BCL6


Figure from BCL6


Figure from BRMS1


Figure from BTRC


Figure from CARD10


Figure from CARD8


Figure from CD74


Figure from COPS2


Figure from CXCR1


Figure from CXXC5


Figure from CYLD


Figure from DGKA


Figure from DPP4


Figure from E2F4


Figure from EIF2AK2


Figure from ERRFI1


Figure from FAS


Figure from FAS


Figure from FGFR1


Figure from FPR1


Figure from GFI1


Figure from GSK3B


Figure from IER3


Figure from IL17A


Figure from IL23A


Figure from ILK


Figure from ILK


Figure from ING4


Figure from LIMD1


Figure from LPAR2


Figure from MIR146B


Figure from MST1


Figure from NFKB1


Figure from NGFR


Figure from NKX2-3


Figure from NR3C1


Figure from PRKCI


Figure from RNF11


Figure from RNF11


Figure from SGK1


Figure from SIAH2


Figure from TGFBR3


Figure from TRIM27


Figure from USP15


Figure from VAV3


Figure from WWTR1


Figure from CXCL12


Figure from ZAP70

Contributor(s)

WrittenOct 2009Jean-Loup Huret
UpdatedJun 2017Jean-Loup Huret and Philippe Dessen

Citation

This paper should be referenced as such :
, Huret JL, Dessen P.. NF-kB. Atlas Genet Cytogenet Oncol Haematol. Jun 2017 .
URL : http://AtlasGeneticsOncology.org/Categories/NF-kB.html


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jun 26 12:06:18 CEST 2017

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