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AKT signalling


Section Editor - Robin C.Muise-Helmericks

( - )

Deep Insight

Adiponectin and cancer
Mechanisms and regulation of autophagy in mammalian cells
Th17 cells: inflammation and regulation

Genes specifically involved in AKT signalling

ACLY (ATP citrate lyase)2012-10
ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif, 9)2013-12
AFAP1L2 (actin filament associated protein 1-like 2)2014-01
AKT1S1 (AKT1 substrate 1 (proline-rich))2014-11
AKT2 (v-akt murine thymoma viral oncogene homolog 2)2007-07
AKT3 (v-akt murine thymoma viral oncogene homolog 3, Protein Kinase B gamma)2007-07
ATF4 (activating transcription factor 4 (tax-responsive enhancer element B67))2009-10
AXL (AXL receptor tyrosine kinase)2010-02
CASP8 (Caspase 8, Apoptosis-Related Cysteine Peptidase)2013-11
CD74 (CD74 molecule, major histocompatibility complex, class II invariant chain)2014-03
CXCL10 (chemokine (C-X-C motif) ligand 10)2012-05
CXCL12 (chemokine (C-X-C motif) ligand 12)2015-08
CXCR1 (chemokine (C-X-C motif) receptor 1)2013-06
DDIT4 (DNA-damage-inducible transcript 4)2012-12
DIRAS3 (DIRAS family, GTP-binding RAS-like 3)2009-09
DLC1 (deleted in liver cancer 1)2010-05
DLG1 (discs, large homolog 1 (Drosophila))2015-01
DPP4 (dipeptidyl-peptidase 4)2012-11
DUSP26 (dual specificity phosphatase 26)2015-05
EEF1A2 (eukaryotic translation elongation factor 1 alpha 2)2008-04
EEF2K (eukaryotic elongation factor 2 kinase)Need an author
EIF2AK2 (eukaryotic translation initiation factor 2-alpha kinase 2)2012-03
EIF4B (eukaryotic translation initiation factor 4B)2014-04
EIF4EBP1 (Eukaryotic translation initiation factor 4E binding protein 1)2012-03
EPHA2 (EPH receptor A2)2012-03
EPHB6 (EPH receptor B6)2012-02
EPS8 (epidermal growth factor receptor pathway substrate 8)2011-04
ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian))2012-05
FAM57A (family with sequence similarity 57, member A)2010-08
FAS (Fas cell surface death receptor)2014-11
FGFR4 (fibroblast growth factor receptor 4)2012-05
FKBP5 (FK506 binding protein 5)2013-10
FKBP8 (FK506 binding protein 8, 38kDa)2012-01
FMNL1 (formin like 1)2016-10
FOSL1 (FOS-like antigen 1)2012-11
FPR1 (formyl peptide receptor 1)2012-06
GAS5 (growth arrest-specific 5 (non-protein coding))2009-10
GNA11 (guanine nucleotide binding protein (G protein), alpha 11 (Gq class))2011-03
GNAQ (guanine nucleotide binding protein (G protein), q polypeptide)2011-03
GRM1 (glutamate receptor, metabotropic 1)2013-08
GRN (Granulin)2007-10
GSK3B (glycogen synthase kinase 3 beta)2010-04
GUCY2C (guanylate cyclase 2C (heat stable enterotoxin receptor))2014-02
HSPB8 (heat shock 22kDa protein 8)2014-03
IGF1 (Insulin-Like Growth Factor 1 (Somatomedin C))2013-11
IL7R (interleukin 7 receptor)2013-08
ILK (integrin-linked kinase)2014-08
ING3 (inhibitor of growth family, member 3)2014-11
IRS1 (insulin receptor substrate 1)2013-03
IRS2 (insulin receptor substrate 2)2016-05
ITGA6 (integrin, alpha 6)2013-04
KITLG (KIT ligand)2000-06::2014-08
LGI1 (Leucine-rich, Glioma Inactivated protein 1 precursor)2007-07
LPAR2 (lysophosphatidic acid receptor 2)2012-11
MARCKS (myristoylated alanine-rich protein kinase C substrate)2012-11
MECOM (Ecotropic Viral Integration Site 1 (EVI1) and Myelodysplastic Syndrome 1 (MDS1-EVI1)2007-12::2015-05
MIR200C (microRNA 200c)2014-07
MST1 (macrophage stimulating 1 (hepatocyte growth factor-like))2013-05
MTCP1 (Mature T Cell Proliferation 1)1998-03
MTOR (FK506 binding protein 12-rapamycin associated protein 1)2008-06
NAMPT (nicotinamide phosphoribosyltransferase)2012-06
NGFR (nerve growth factor receptor)2015-12
NME1 (NME/NM23 nucleoside diphosphate kinase 1)2013-02
NUAK1 (NUAK family, SNF1-like kinase, 1)2014-03
PA2G4 (proliferation-associated 2G4, 38kDa)2011-09
PEA15 (phosphoprotein enriched in astrocytes 15)2012-05
PGR (progesterone receptor)Need an author
PIK3CA (phosphoinositide-3-kinase, catalytic, alpha polypeptide)2009-04::Reserved
PIK3CD (phosphoinositide-3-kinase, catalytic, delta polypeptide)2011-02
PIK3R1 (phosphoinositide-3-kinase, regulatory subunit 1 (alpha))2012-05
PLA2G4A (phospholipase A2, group IVA (cytosolic, calcium-dependent))2009-12
PLCG1 (Phospholipase C, Gamma 1)2014-02
PLD1 (phospholipase D1, phosphatidylcholine-specific)2010-10
PLD2 (phospholipase D2)2013-04
PML (promyelocytic leukemia)2014-05
PPP2R1A (protein phosphatase 2 regulatory subunit A, alpha)2016-03
PRKCI (protein kinase C, iota)2012-06
PSEN2 (presenilin 2 (Alzheimer disease 4))2010-04
PTEN (Phosphatase and Tensin homolog deleted on chromosome Ten)1999-07
RAB31 (Ras-related protein in brain 31)2016-02
RACGAP1 (Rac GTPase activating protein 1)2016-02
RANBP2 (RAN binding protein 2)2014-08
REST (RE1-silencing transcription factor)2010-05
RHOB (ras homolog gene family, member B)2007-02
RLN2 (relaxin 2)2009-11
ROS1 (ROS proto-oncogene 1 , receptor tyrosine kinase)2014-01
S100A4 (S100 Calcium Binding Protein A4)2013-11
S100A7 (S100 calcium binding protein A7)2010-04
S100A8 (S100 calcium binding protein A8)2011-02
S100A9 (S100 calcium binding protein A9)2011-02
SERPINB3 (Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3)2014-06
SET (SET nuclear oncogene)2013-05
SGK1 (serum/glucocorticoid regulated kinase 1)2014-09
SIRT1 (sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae))2014-12
SLC1A5 (solute carrier family 1 (neutral amino acid transporter), member 5)2014-02
SRSF1 (serine/arginine-rich splicing factor 1)2011-11
STMN1 (stathmin 1)2014-05
SULF2 (sulfatase 2)2013-04
SYK (spleen tyrosine kinase)2016-03
TACC2 (transforming, acidic coiled-coil containing protein 2)2013-08
TCL1B (T-cell leukemia/lymphoma 1B)2008-01
TFF3 trefoil factor 3 (intestinal)2001-03
THRB (Thyroid Hormone Receptor, Beta)2013-11
THY1 (Thy-1 cell surface antigen)2010-01
TPD52 (tumor protein D52)2010-09
TRPV2 (transient receptor potential cation channel, subfamily V, member 2)2012-03
TSC1 (Tuberous Sclerosis 1)2001-11
TSC2 (tuberous sclerosis 2)2001-11
TYMP (thymidine phosphorylase)2010-03
VAV3 (vav 3 guanine nucleotide exchange factor)2010-08
VMP1 (vacuole membrane protein 1)2011-11

Other Genes involved in AKT signalling

PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha)

Iconography


Figure from Autophagy


Figure from ADAMTS9


Figure from AFAP1L2


Figure from AKT1


Figure from AKT1S1


Figure from AKT2


Figure from AKT2


Figure from AKT3


Figure from ATF4


Figure from AXL


Figure from CD74


Figure from CXCR1


Figure from DIRAS3


Figure from DLC1


Figure from DPP4


Figure from DUSP26


Figure from DUSP26


Figure from EEF1A2


Figure from EIF2AK2


Figure from EIF4B


Figure from EIF4B


Figure from EIF4B


Figure from EPHA2


Figure from EPHA2


Figure from EPHB6


Figure from ERBB3


Figure from EVI1


Figure from FAM57A


Figure from FAS


Figure from FAS


Figure from FGFR1


Figure from FGFR4


Figure from FKBP8


Figure from FKBP8


Figure from FOSL1


Figure from FOSL1


Figure from FPR1


Figure from FRAP1


Figure from FRAP1


Figure from GRM1


Figure from GRM1


Figure from GSK3B


Figure from HSPB8


Figure from HSPB8


Figure from ILK


Figure from ILK


Figure from ING3


Figure from LGI1


Figure from LPAR2


Figure from MST1


Figure from NGFR


Figure from NUAK1


Figure from PEA15


Figure from PIK3CA


Figure from PLCG1


Figure from PRKCI


Figure from RANBP2


Figure from RANBP2


Figure from SGK1


Figure from SLC1A5


Figure from SRSF1


Figure from STMN1


Figure from STMN1


Figure from STMN1


Figure from TACC2


Figure from TRPV2


Figure from CXCL12

Contributor(s)

WrittenOct 2009Jean-Loup Huret
UpdatedOct 2017Jean-Loup Huret and Philippe Dessen

Citation

This paper should be referenced as such :
, Huret JL, Dessen P.. PI3K-AKT-mTOR. Atlas Genet Cytogenet Oncol Haematol. Oct 2017 .
URL : http://AtlasGeneticsOncology.org/Categories/PI3K-AKT-mTOR.html


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Oct 19 13:29:58 CEST 2017

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