Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Deep Insight

Understanding the structure and function of ASH2L
Cell cycle, checkpoints and cancer
The contribution of circadian rhythms to cancer formation and mortality
Common fragile sites and genomic instability
FOXP3 expression in tumor cells and its role in cancer progression
Mechanisms of rDNA silencing and the Nucleolar Remodelling Complex (NoRC)
Insights into structure and function of human PWWP domains


ARID1A (AT rich interactive domain 1A (SWI-like))
ASH2L (ash2 (absent, small, or homeotic)-like (Drosophila))
ATF4 (activating transcription factor 4 (tax-responsive enhancer element B67))
ATF5 (activating transcription factor 5)
ATMIN (ATM Interactor)
BCAS3 (breast carcinoma amplified sequence 3)
CCND1 (B-cell leukemia/lymphoma 1)
BCL6 (B-Cell Lymphoma 6)
BCLAF1 (BCL2-associated transcription factor 1)
BEX1 (brain expressed, X-linked 1)
BEX2 (brain expressed X-linked 2)
BRCA2 (breast cancer 2, early onset)
BRD3 ((bromodomain containing 3)
CASP8AP2 (caspase 8 associated protein 2)
CASZ1 (castor zinc finger 1)
CBX7 (chromobox homolog 7)
CDC73 (cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae))
CEBPA (CCAAT/enhancer binding protein (C/EBP), alpha)
CENPW (centromere protein W)
CHD6 (chromodomain helicase DNA binding protein 6)
CIC (capicua transcriptional repressor)
CRTC2 (CREB regulated transcription coactivator 2)
CSNK2A2 (casein kinase 2 alpha 2)
CTCF (CCCTC-binding factor (zinc finger protein))
CTDSPL (CTD (Carboxy-Terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase-Like)
DDX1 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 1)
DDX5 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 5)
DIRAS3 (DIRAS family, GTP-binding RAS-like 3)
DLX4 (distal-less homeobox 4)
DNMT3A (DNA (cytosine-5-)-methyltransferase 3 alpha)
DNMT3B (DNA (cytosine-5-)-methyltransferase 3 beta)
DOT1L (DOT1 like histone H3K79 methyltransferase)
DYRK1A (dual-specificity tyrosine- (Y)-phosphorylation regulated kinase 1A)
TCF3 (transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47))
E2F4 (E2F transcription factor 4, p107/p130-binding)
EEF1D (eukaryotic translation elongation factor 1 delta)
EHF (ets homologous factor)
EHMT2 (euchromatic histone-lysine N-methyltransferase 2)
EIF3A (eukaryotic translation initiation factor 3, subunit A)
ELL (eleven nineteen lysin rich leukemia gene)
ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian))
ETV1 (ets variant 1)
MECOM (Ecotropic Viral Integration Site 1 (EVI1) and Myelodysplastic Syndrome 1 (MDS1-EVI1)
EWSR1 (Ewing sarcoma breakpoint region 1)
EYA2 (EYA transcriptional coactivator and phosphatase 2)
FLI1 (Friend leukemia virus integration 1)
FOSL1 (FOS-like antigen 1)
FOXA1 (forkhead box A1)
FOXF1 (forkhead box F1)
FOXQ1 (forkhead box Q1)
FUBP1 (far upstream element (FUSE) binding protein 1)
GATA1 (GATA binding protein 1 (globin transcription factor1))
GATA3 (GATA binding protein 3)
GATA6 (GATA binding protein 6)
GFI1B (growth factor independent 1B transcription repressor)
HDAC2 (histone deacetylase 2)
HELLS (Helicase, Lymphoid-Specific)
HIPK2 (homeodomain interacting protein kinase 2)
HLTF (helicase-like transcription factor)
HMGA2 (high mobility group AT-hook 2)
HMGA1 (High mobility group protein (non histone chromosomal) isoform I and Y)
HMGN5 (High Mobility Group Nucleosome binding domain 5)
HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1)
HNRNPD (heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa))
ING3 (inhibitor of growth family, member 3)
ING4 (inhibitor of growth family, member 4)
INTS6 (integrator complex subunit 6)
CCAR2 cell cycle and apoptosis regulator 2
KLLN (killin, p53-regulated DNA replication inhibitor)
LIMD1 (LIM domains containing 1)
LMO1 (LIM domain only 1 (rhombotin 1))
MAZ (MYC Associated Zinc Finger Protein)
MBD4 (methyl-CpG binding domain protein 4)
MED28 (mediator complex subunit 28)
MEIS1 (Meis homeobox 1)
MIER1 (mesoderm induction early response 1 homolog (Xenopus laevis))
RIOX2 (ribosomal oxygenase 2)
MITF (microphthalmia-associated transcription factor)
MIXL1 (Mix1 homeobox-like 1 (Xenopus laevis))
MTA3 (metastasis associated 1 family, member 3 )
MYBBP1A (MYB binding protein (P160) 1a)
NANOG (Nanog homeobox)
NCOA1 (Nuclear receptor coactivator 1)
NFATC2 (nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2)
NKX2-1 (NK2 homeobox 1)
NKX2-3 (NK2 homeobox 3)
NR0B1 (nuclear receptor subfamily 0, group B, member 1)
NR3C1 (nuclear receptor subfamily 3, group C, member 1/glucocorticoid receptor)
NR5A1 (nuclear receptor subfamily 5, group A, member 1)
NUAK1 (NUAK family, SNF1-like kinase, 1)
EP300 (E1A binding protein p300)
PA2G4 (proliferation-associated 2G4, 38kDa)
PAF1 (Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae))
PARK7 (Parkinsonism associated deglycase)
PARP1 (poly(ADP-ribose) polymerase 1)
PBRM1 (polybromo 1)
PGR (progesterone receptor)
PHOX2B (paired-like homeobox 2b)
PIAS1 (protein inhibitor of activated STAT, 1)
PIAS3 (protein inhibitor of activated STAT, 3)
PML (promyelocytic leukemia)
POU1F1 (POU class 1 homeobox 1)
POU3F2 (POU class 3 homeobox 2)
PPP1R8 (protein phosphatase 1, regulatory (inhibitor) subunit 8)
PPP2R1A (protein phosphatase 2 regulatory subunit A, alpha)
PTK6 (protein tyrosine kinase 6)
PYGO2 (pygopus family PHD finger 2)
RASSF5 (Ras association (RalGDS/AF-6) domain family member 5)
RECQL5 (RecQ protein-like 5)
REST (RE1-silencing transcription factor)
RGS17 (regulator of G-protein signaling 17)
RPL26 (ribosomal protein L26)
RREB1 (Ras Responsive Element Binding Protein 1)
S100A2 (S100 calcium binding protein A2)
SETD2 (SET domain containing 2, histone lysine methyltransferase)
SET (SET nuclear oncogene)
SGK1 (serum/glucocorticoid regulated kinase 1)
SIRT1 (sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae))
SLC4A1 (solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group))
SLC6A4 (solute carrier family 6 member 4)
SMYD2 (SET and MYND domain containing 2)
SMYD3 (SET and MYND domain containing 3)
SNW1 (SNW domain containing 1)
SOX10 (SRY (sex determining region Y)-box 10)
SOX11 (SRY (sex determining region Y)-box 11)
SOX2 (SRY (sex determining region Y)-box 2)
SREBF1 (sterol regulatory element binding transcription factor 1)
SSX2 (synovial sarcoma, X breakpoint 2)
TACC2 (transforming, acidic coiled-coil containing protein 2)
TAF15 (TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa)
TBX3 (T-box 3)
TERF2 (telomeric repeat binding factor 2)
TET2 (tet methylcytosine dioxygenase 2)
TFAP2A (transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha))
TFAP2C (transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma))
THRAP3 (thyroid hormone receptor associated protein 3)
THRB (Thyroid Hormone Receptor, Beta)
THRSP (thyroid hormone responsive)
TNIK (TRAF2 and NCK interacting kinase)
TOP1 (topoisomerase (DNA) 1)
TRIM27 (tripartite motif containing 27)
UBD (ubiquitin D)
USF1 (upstream transcription factor 1)
USP15 (ubiquitin specific peptidase 15)
WWTR1 (WW domain containing transcription regulator 1)
XPO1 (exportin 1 (CRM1 homolog, yeast))
YBX1 (Y box binding protein 1)
YEATS4 (YEATS domain containing 4)
ZBTB33 (zinc finger and BTB domain containing 33)
ZFX (zinc finger protein, X-linked)
ZMYND10 (zinc finger, MYND-type containing 10)


Figure from "Cell_cycle,_checkpoints_and_cancer"

Figure from "Cell_cycle,_checkpoints_and_cancer"

Figure from "Cell_cycle,_checkpoints_and_cancer"

Figure from The_contribution_of_circadian_rhythms_to_cancer_formation_and_mortality

Figure from TranscripFactors

Figure from ASH2L

Figure from ASH2L

Figure from ATF4

Figure from ATF5

Figure from ATMIN

Figure from BCL6

Figure from BCL6

Figure from BCLAF1

Figure from BRCA2

Figure from CASZ1

Figure from CBX7

Figure from CENPW

Figure from CHD6

Figure from CIC

Figure from CTDSPL

Figure from DDX1

Figure from DDX5

Figure from DIRAS3

Figure from DYRK1A

Figure from TCF3

Figure from E2F4

Figure from EHF

Figure from EHMT2

Figure from EIF3A

Figure from ERBB3

Figure from EWSR1

Figure from EYA2

Figure from FLI1

Figure from FOSL1

Figure from FOSL1

Figure from FOXA1

Figure from FOXQ1

Figure from FOXQ1

Figure from FUBP1

Figure from FUBP1

Figure from GFI1B

Figure from HDAC2

Figure from HELLS

Figure from HLTF

Figure from HMGA1

Figure from HNRNPD

Figure from ING3

Figure from ING4

Figure from KIAA1967

Figure from LIMD1

Figure from MBD4

Figure from MEIS1

Figure from MEIS1

Figure from MIER1

Figure from MINA

Figure from MIXL1

Figure from MTA3

Figure from MTA3

Figure from MYBBP1A

Figure from NANOG

Figure from NKX2-1

Figure from NKX2-3

Figure from NR3C1

Figure from NR5A1

Figure from NUAK1

Figure from PA2G4

Figure from PAF1

Figure from PIAS1

Figure from PIAS3

Figure from POU1F1

Figure from POU3F2

Figure from PPP1R8

Figure from PTK6

Figure from REST

Figure from RGS17

Figure from RPL26

Figure from RREB1

Figure from S100A2

Figure from SGK1

Figure from SIRT1

Figure from SIRT1

Figure from SMYD2

Figure from SMYD3

Figure from SOX10

Figure from SOX11

Figure from SSX2

Figure from TACC2

Figure from TBX3

Figure from TET2

Figure from TFAP2A

Figure from TOP1

Figure from TRIM27

Figure from USF1

Figure from USP15

Figure from WWTR1

Figure from ZBTB33

Figure from ZFX

Figure from ZMYND10

Figure from ARID1A

Figure from ETV1

Figure from HMGN5

Figure from NFATC2

Figure from NR0B1

Figure from CTCF

Figure from GATA3

Figure from KLLN

Figure from PBRM1

Figure from PHOX2B

Figure from SREBF1

Figure from TNIK

Figure from DNMT3A

Figure from EEF1D

Figure from EHF

Figure from MAZ

Figure from MED28

Figure from PYGO2

Figure from SETD2

Figure from CEBPA

Figure from CSNK2A2

Figure from HMGA2

Figure from HNRNPA1

Figure from TERF2

Figure from DLX4

Figure from EWSR1

Figure from BCL6

Figure from SOX2

Figure from PPP2R1A

Figure from SLC4A1

Figure from PARP1

Figure from PGR

Figure from NCOA1

Figure from PML


WrittenOct 2009Jean-Loup Huret
UpdatedJan 2022Jean-Loup Huret and Philippe Dessen


This paper should be referenced as such :
, Huret JL, Dessen P.. Transcription. Atlas Genet Cytogenet Oncol Haematol. Jan 2022 .

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 20 18:23:22 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

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