Atlas of Genetics and Cytogenetics in Oncology and Haematology


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Transcription factor

Deep Insight

MTA1 of the MTA (metastasis-associated) gene family and its encoded proteins: molecular and regulatory functions and role in human cancer progression
Mechanisms of rDNA silencing and the Nucleolar Remodelling Complex (NoRC)
The roles of SRA1 gene in breast cancer
Transcription factors
Role of TWIST proteins in cancer progression

Genes

ACLY (ATP citrate lyase)
ACTN4 (actinin, alpha 4)
MLLT10 (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10)
MLLT6 (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6)
AFF1 (AF4/FMR2 family, member 1)
MLLT3 (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3)
AKT1 (v-akt murine thymoma viral oncogene homolog 1)
RUNX1 (runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene))
ARID5B (AT rich interactive domain 5B (MRF1-like))
AR (Androgen Receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease))
ARNT (aryl hydrocarbon receptor nuclear translocator)
ASCL1 (Achaete-scute homolog 1 or achaete-scute complex homolog 1)
ZFHX3 (AT-binding transcription factor 1)
ATF1 (activating transcription factor 1)
ATF2 (activating transcription factor 2)
ATF4 (activating transcription factor 4 (tax-responsive enhancer element B67))
ATMIN (ATM Interactor)
BACH2 (BTB and CNC homology 1, basic leucine zipper transcription factor 2)
BCAS4 (breast carcinoma amplified sequence 4)
BCL11A (B-cell lymphoma/leukemia 11A)
BCL11B (B-cell lymphoma/leukaemia 11B)
BCL6 (B-Cell Lymphoma 6)
BCL9 (B-cell CLL/lymphoma 9)
BEX1 (brain expressed, X-linked 1)
BEX2 (brain expressed X-linked 2)
CAMTA1 (calmodulin binding transcription activator 1)
CBFA2T3 (core-binding factor, runt domain, alpha subunit 2; translocated to, 3)
CBFB (subunit b of core binding factor)
CBX7 (chromobox homolog 7)
CDX2 (caudal-related homeobox 2)
CEBPA (CCAAT/enhancer binding protein (C/EBP), alpha)
CEBPE (CCAAT/enhancer binding protein epsilon)
TRIP11 (thyroid hormone receptor interactor 11)
CHD5 (chromodomain helicase DNA binding protein 5)
CIC (capicua transcriptional repressor)
CITED2 (Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2)
CITED4 (Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4)
COPS2 (COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis))
CREB3L2 (cAMP responsive element binding protein 3-like 2)
CUX1 (cut-like homeobox 1)
DAXX (death-associated protein 6)
DDIT3 (DNA damage inducible transcript 3)
DDR1 (discoidin domain receptor tyrosine kinase 1)
DDX1 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 1)
DEFB1 (defensin, beta 1)
DLX2 (distal-less homeobox 2)
DLX4 (distal-less homeobox 4)
DLX5 (distal-less homeobox 5)
DLX6 (distal-less homeobox 6)
DNMT1 (DNA (cytosine-5-)-methyltransferase 1))
DNMT3A (DNA (cytosine-5-)-methyltransferase 3 alpha)
DYRK1B (dual-specificity tyrosine- (Y)-phosphorylation regulated kinase 1B)
E2F3 (E2F transcription factor 3)
E2F4 (E2F transcription factor 4, p107/p130-binding)
E2F6 (E2F transcription factor 6)
EGR1 (Early Growth Response 1)
EHF (ets homologous factor)
EHMT2 (euchromatic histone-lysine N-methyltransferase 2)
EIF2AK2 (eukaryotic translation initiation factor 2-alpha kinase 2)
ELF4 (E74-like factor 4 (ets domain transcription factor))
MLLT1 (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1)
ENO1 (Enolase 1, (alpha))
EPAS1 (Endothelial PAS Domain Protein 1)
EPS8 (epidermal growth factor receptor pathway substrate 8)
ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian))
ERG (v-ets erythroblastosis virus E26 oncogene like (avian))
ESR2 (Estrogen Receptor 2 (ER beta))
ESRRA (estrogen-related receptor alpha)
ESRRG (estrogen-related receptor gamma)
RUNX1T1 (runt-related transcription factor 1; translocated to, 1 (cyclin D-related))
ETS1 (v-ets erythroblastosis virus E26 oncogene homolog 1 (avian))
ETS2 (v-ets erythroblastosis virus E26 oncogene homolog 2 (avian))
ETV1 (ets variant 1)
ETV6 (ets variant 6)
MECOM (Ecotropic Viral Integration Site 1 (EVI1) and Myelodysplastic Syndrome 1 (MDS1-EVI1)
FOSL1 (FOS-like antigen 1)
FOXC1 (forkhead box C1)
FOXE1 (forkhead box E1 (thyroid transcription factor 2))
FOXF1 (forkhead box F1)
FOXO1 (Forkhead box O1)
FOXP1 (Forkhead box P1)
FOXQ1 (forkhead box Q1)
FPR1 (formyl peptide receptor 1)
GATA1 (GATA binding protein 1 (globin transcription factor1))
GATA2 (GATA binding protein 2)
GATA3 (GATA binding protein 3)
GATA6 (GATA binding protein 6)
GFI1B (growth factor independent 1B transcription repressor)
GFI1 (growth factor independent 1 transcription repressor)
GLI1 (glioma-associated oncogene homolog 1)
GLIS2 (GLIS family zinc finger 2)
GSK3B (glycogen synthase kinase 3 beta)
HDAC1 (histone deacetylase 1)
HIC1 (Hypermethylated in Cancer 1)
HLTF (helicase-like transcription factor)
MNX1 (homeo box HB9)
HOXA11 (homeobox A11)
HOXA9 (homeobox A9)
HOXC13 (homeobox C13)
HOXC8 (homeobox C8)
HSPBAP1 (HSPB (heat shock 27kDa) associated protein 1)
ID1 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein)
ID2 (Inhibitor Of DNA Binding 2, Dominant Negative Helix-Loop-Helix Protein)
IGFBP6 (insulin-like growth factor binding protein 6)
IKZF1 (Ikaros family zinc finger 1)
IKZF2 (IKAROS family zinc finger 2)
ILK (integrin-linked kinase)
ING2 (inhibitor of growth family, member 2)
ING4 (inhibitor of growth family, member 4)
IRF1 (interferon regulatory factor 1)
IRF4 (interferon regulatory factor 4)
KDM5A (Jumonji, AT rich interactive domain 1A (RBBP2-like))
JAZF1 (JAZF zinc finger 1)
KLF6 (Krüppel like factor 6)
AFF3 (lymphoid nuclear protein related to AF4)
LDB1 (LIM domain binding 1)
LIMD1 (LIM domains containing 1)
LYL1 (lymphoblastic leukemia derived sequence 1)
MAFA (v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian))
MAFB (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B)
MAF (v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian))
MBD4 (methyl-CpG binding domain protein 4)
MEF2D (myocyte enhancer factor 2D)
MEIS1 (Meis homeobox 1)
MEN1 (multiple endocrine neoplasia I)
CIITA (MHC class II transactivator)
RIOX2 (ribosomal oxygenase 2)
MIR200C (microRNA 200c)
MIXL1 (Mix1 homeobox-like 1 (Xenopus laevis))
MLF1 (myelodysplasia/myeloid leukemia factor 1)
MN1 (meningioma 1)
MSX2 (Msh Homeobox 2)
MTA1 (metastasis-associated gene 1)
MTA3 (metastasis associated 1 family, member 3 )
MXI1 (MAX interactor 1)
MYB (v-myb myeloblastosis viral oncogene homolog (avian))
MYBL1 (v-myb myeloblastosis viral oncogene homolog (avian)-like 1)
MYBL2 (v-myb myeloblastosis viral oncogene homolog (avian)-like 2)
MYC (MYC proto-oncogene, bHLH transcription factor)
KAT6A (MYST histone acetyltransferase (monocytic leukemia) 3
KAT6B (MYST histone acetyltransferase (monocytic leukemia) 4)
NACC1 (nucleus accumbens associated 1, BEN and BTB (POZ) domain containing)
NAMPT (nicotinamide phosphoribosyltransferase)
NANOG (Nanog homeobox)
NCOA3 (Nuclear Receptor Coactivator 3)
NFE2L2 (nuclear factor, erythroid 2-like 2)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKX2-1 (NK2 homeobox 1)
NKX2-2 (NK2 homeobox 2)
NKX2-3 (NK2 homeobox 3)
NKX3-1 (NK3 homeobox 1)
MYCN (v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian))
NONO (non-POU domain containing, octamer-binding)
NR1H4 (nuclear receptor subfamily 1, group H, member 4)
NR3C1 (nuclear receptor subfamily 3, group C, member 1/glucocorticoid receptor)
NR4A1 (nuclear receptor subfamily 4, group A, member 1)
NRF1 (nuclear respiratory factor 1)
NRIP1 (nuclear receptor interacting protein 1)
NSD1 (Nuclear receptor-binding, su (var), enhancer-of-zeste and trithorax domain-containing protein 1
OTX2 (orthodenticle homeobox 2)
PA2G4 (proliferation-associated 2G4, 38kDa)
PASD1 (PAS domain containing 1)
PAX2 (Paired box gene 2)
PAX3 (paired box gene 3 (Waardenburg syndrome 1))
PAX5 (paired box gene 5)
PAX6 (paired box 6)
PAX8 (paired box 8)
PAX9 (Paired box gene 9)
PBRM1 (polybromo 1)
PBX1 (pre-B-cell leukemia homeobox 1)
PDX1 (pancreatic and duodenal homeobox 1)
PGR (progesterone receptor)
PHOX2B (paired-like homeobox 2b)
PIM1 (pim-1 oncogene)
PLAG1 (Pleomorphic adenoma gene 1)
PLAGL1 (Pleomorphic adenoma gene-like 1)
PML (promyelocytic leukemia)
POU1F1 (POU class 1 homeobox 1)
POU3F2 (POU class 3 homeobox 2)
POU6F2 (POU domain, class 6, transcription factor 2)
PRDM16 (PR domain containing 16)
PRDM1 (PR domain containing 1, with ZNF domain)
PRDM2 (PR domain containing 2, with ZNF domain)
PRRX2 (paired related homeobox 2)
PSEN2 (presenilin 2 (Alzheimer disease 4))
SFPQ (PTB-associated splicing factor)
PSIP1 (PC4 and SFRS1 interacting protein 1)
RACGAP1 (Rac GTPase activating protein 1)
RARA (Retinoic acid receptor, alpha)
RBBP7 (retinoblastoma binding protein 7)
LMO2 (LIM domain only 2 (rhombotin-like 1))
REST (RE1-silencing transcription factor)
RUNX2 (Runt-related transcription factor 2)
S100A4 (S100 Calcium Binding Protein A4)
SDCBP (syndecan binding protein (syntenin))
SGK1 (serum/glucocorticoid regulated kinase 1)
SIRT1 (sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae))
SIX1 (sine oculis homeobox homolog 1) (mammalian)
SMYD3 (SET and MYND domain containing 3)
SNAI1 (snail homolog 1 (Drosophila))
SNAI2 (SNAIL HOMOLOG 2)
SOX10 (SRY (sex determining region Y)-box 10)
SOX2 (SRY (sex determining region Y)-box 2)
SOX4 (SRY (sex determining region Y)-box 4)
SS18 (synovial sarcoma translocation, chromosome 18)
SS18L1 (synovial sarcoma translocation gene on chromosome 18-like 1)
STAT3 (Signal Transducer and Activator of Transcription 3)
SYK (spleen tyrosine kinase)
TACC2 (transforming, acidic coiled-coil containing protein 2)
TACC3 (transforming, acidic coiled-coil containing protein 3)
TAL1 (T-cell acute leukemia 1)
TAL2 (T-cell acute lymphoblastic leukemia 2)
TBX2 (T-box 2)
TBX3 (T-box 3)
TCF12 (transcription factor 12)
NR4A3 (nuclear receptor subfamily 4, group A, member 3)
TFAP2C (transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma))
TFE3 (transcription factor E3)
TFEB (transcription factor EB)
TGFB1 (transforming growth factor, beta 1)
THRAP3 (thyroid hormone receptor associated protein 3)
THRB (Thyroid Hormone Receptor, Beta)
TNKS (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase)
TP63 (tumor protein p63)
TRPV2 (transient receptor potential cation channel, subfamily V, member 2)
TWIST1 (twist homolog 1 (Drosophila))
TWIST2 (twist family BHLH transcription factor 2)
VCP (valosin containing protein)
NSD3 (nuclear receptor binding SET domain protein 3)
WT1 (Wilms' tumor suppressor gene)
YAP1 (Yes-associated protein 1, 65kDa)
ZAP70 (zeta-chain (TCR) associated protein kinase 70kDa)
ZNF217 (zinc finger protein 217)
ZNF384 (Zinc Finger protein 384)

Iconography


Figure from MTAinCance


Figure from MTAinCance


Figure from MTAinCance


Figure from TranscripFactors


Figure from TranscripFactors


Figure from TranscripFactors


Figure from TranscripFactors


Figure from TranscripFactors


Figure from RUNX1


Figure from AR


Figure from ARNT


Figure from ASCL1


Figure from ATF2


Figure from ATF4


Figure from ATMIN


Figure from BCL11A


Figure from BCL11B


Figure from BCL6


Figure from BCL6


Figure from BCL6


Figure from BIN1


Figure from CAMTA1


Figure from CBFb


Figure from CBX7


Figure from CEBPA


Figure from CHD5


Figure from COPS2


Figure from DAXX


Figure from DDIT3


Figure from DDX1


Figure from DLX2


Figure from DLX5


Figure from DNMT1


Figure from E2F3


Figure from E2F4


Figure from E2F6


Figure from EGR1


Figure from EGR1


Figure from EHF


Figure from EHMT2


Figure from EIF2AK2


Figure from ELF4


Figure from ELF4


Figure from ENO1


Figure from EPAS1


Figure from ERBB3


Figure from ESRRA


Figure from ESRRG


Figure from ETS2


Figure from ETV6


Figure from FOSL1


Figure from FOSL1


Figure from FOXE1


Figure from FOXP1


Figure from FOXQ1


Figure from FOXQ1


Figure from FPR1


Figure from GATA1


Figure from GFI1B


Figure from HOXC8


Figure from IGFBP6


Figure from ILK


Figure from ILK


Figure from MAFB


Figure from MEIS1


Figure from MEIS1


Figure from NACC1


Figure from NANOG


Figure from NFE2L2


Figure from NFE2L2


Figure from NFE2L2


Figure from NFE2L2


Figure from NFE2L2


Figure from NFE2L2


Figure from NKX2-3


Figure from NMYC


Figure from NR1H4


Figure from NR3C1


Figure from POU1F1


Figure from POU3F2


Figure from SGK1


Figure from TACC2


Figure from TBX3


Figure from TP63


Figure from TRPV2


Figure from TWIST2


Figure from CIC


Figure from ZAP70

Contributor(s)

WrittenOct 2009Jean-Loup Huret
UpdatedOct 2017Jean-Loup Huret and Philippe Dessen

Citation

This paper should be referenced as such :
, Huret JL, Dessen P.. Transcription_factor. Atlas Genet Cytogenet Oncol Haematol. Oct 2017 .
URL : http://AtlasGeneticsOncology.org/Categories/Transcription_factor.html


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Oct 19 13:29:59 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

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