Database	ID	Filename	Title	Datecreated	Authors	Citation	Affiliation	Preleukemia	Malignant	Inborn	Age	Sex	Immuno	Diagnostic	Results
Atlas Genet Cytogenet Oncol Haematol	100030	0106RodriguesID100030.txt	Translocation t(1;6)(p35;p25) in B-cell lymphoproliferative disorder with evolution to Diffuse Large B-cell Lymphoma	07-2007	Elvira D Rodrigues Pereira Velloso, Cristina Ratis, Sérgio A B Brasil, João Carlos Guerra, Nydia Bacal; Cristóvão P Mangueira LM Pitangueira	Rodrigues Pereira Velloso ED, Ratis C, Brasil SAB, Guerra JC, Bacal N, Mangueira LM Pitangueira CP	Clinical Laboratory Hospital Israelita Albert Einstein, São Paulo, Brazil (EDRPV)(CR)(NB)(CPMLMP); Centro de Hematologia São Paulo, São Paulo, Brazil (SABB)(JCG)		+ B- cell Lymphoproliferative disorder for 8 years		75 yrs	F	25% of total bone marrow cells are positive : CD20++, CD22+, CD25+, CD38, CD79b++, HLA-DR, sIgM, sIgD e sKappa ++.	B-cell Lymphoproliferative disorder (Atypical CLL) with evolution to diffuse large B-cell Lymphoma.	 47,XX, t(1;6) (p35;p25),+12[13]/46,XX[7]
Atlas Genet Cytogenet Oncol Haematol	100008	0111CollongeID100008.txt	A new case of t(1;11)(q21;q23) in a child with M1 ANLL	01-2005	Katell Le Du, Eric Jeandidier, Francine Garnache, Pierre Rohrlich, Jean-Luc Bresson, Marie-Agnès Collonge-Rame	Le Du K, Jeandidier E, Garnache F, Rohrlich P, Bresson JL, Collonge-Rame MA	Service de Génétique, Histologie, Biologie du Développement et de la Reproduction.CHU - Place St Jacques, 25030 BESANCON Cedex, France ; Macollongerame@chu-besancon.fr	No preleukemia.	No previous solid tumors.	Prematurity (borth at 33 weeks of gestation).	21 mths	M	CD13+,CD15+,CD65+,CD33+,CD117+, MPO+, MDR-, CD34-, CD36-, CD14-, CD4+, lineage B-, lineage T-.	AML1 (FAB classification), LAM with 11q23 abnormalities (WHO classification).	 46,XY,t(1;11)(q21;q23)[6]
Atlas Genet Cytogenet Oncol Haematol	100040	0112BacherID100040.txt	A Case of Myelodysplastic Syndrome with a Translocation t(1;12)(p36;p13)	08-2008	Ulrike Bacher, Torsten Haferlach, Claudia Haferlach	Bacher U, Haferlach T, Haferlach C	Interdisciplinary Clinic for Stem Cell Transplantation, University of Hamburg, Martinistr. 52, 20246 Germany (UB); MLL, Munich Leukemia Laboratory, Max-Lebsche-Platz 31, 81377 Munich, Germany (TH, CH)	-	-	-	46 yrs	M		Myelodysplastic syndrome - subtype refractory anemia cytopenia with multilineage dysplasia (MDS - RCMD) according to the WHO classification.	 46,XY,t(1;12)(p36;p13) [9]; 46,XY [11]
Atlas Genet Cytogenet Oncol Haematol	100024	0116ZamecnikovaID100024.txt	t(1;16)(q11-12;q11) presented as a der(16)t(1;16) in a patient with acute lymphoblastic leukemia.	05-2007	Adriana Zamecnikova	Zamecnikova A	Kuwait Cancer Control Center, Lab of Cancer Genetics, Department of Hematology, Shuwaikh, 70653 Kuwait	-	-	-	56 yrs	M	Positive for CD45, CD10, CD19, CD34, HLADR, TdT.	Acute Lymphoblastic Leukemia, L1 (pre-B).	 46,XY,der(16)t(1;16)(q11-12;q11) [20]
Atlas Genet Cytogenet Oncol Haematol	100021	0121DalCinID100021.txt	A de novo AML with a t(1;21)(p36;q22) in an elderly patient	03-2007	Paola Dal Cin, Andrew J Yee, Bimalangshu Dey	Dal Cin P, Yee AJ, Dey B	Department of Pathology, Brigham and Women's Hospital	-		-	81 yrs	M	CD33+, CD13+, MPO-, CD41-, CD61-, CD203c- (5% of all blast).	Immunophenotype consistent with the presence of myeloid precursors. Negative markers (CD61,CD41,CD203c) associated with megakaryocytic differentiation; AML M0.	 46,XY,t(1;21)(p36;q22)[15]
Atlas Genet Cytogenet Oncol Haematol	100041	0121ReindlID100041.txt	t(1;21)(p32;q22) as a non-random abnormality in AML M4	08-2009	Lena Reindl, Claudia Haferlach	Reindl L, Haferlach C	MLL, Munich Leukemia Laboratory, Max-Lebsche-Platz 31, Germany	-	-	-	63 yrs	F	Hypercellular bone marrow showed a myelomonocytic blast population. 49.5% blasts were detected in total bone marrow. 30% of the cells were clearly EST positive. Futhermore POX was positive, no ringsiderobalsts were found and erythropoiesis showed dysplasia. Myelomonocytic cells with MPO+ (48%), CD13+ (17%), CD33+ (63%), CD14 (19%) and CD64 (37%).	AML M4	 46,XX,t(1;21)(p32;q22)[15/15].
Atlas Genet Cytogenet Oncol Haematol	100017	0212IakovakiID100017.txt	Reciprocal translocation t(2;12)(q31;p13) in a case of CMML	11-2006	Despina Iakovaki, Markos Fisfis, Katy Stefanoudaki, Georgia Bardi	Iakovaki D, Fisfis M, Stefanoudaki K, Bardi G	BioAnalytica-GenoType SA, Molecular Cytogenetic Research and Applications, Athens, Greece / gbardi@genotypos.gr ; Department of Hematology, "Amalia Fleming" General Hospital, Athens, Greece / stefanoudaki@otenet.gr	-	-	-	78 yrs	M		Chronic myelomonocytic leukemia (CMML)	 46,XY,t(2;12)(q31;p13)[22]/47,idem,+21[3].
Atlas Genet Cytogenet Oncol Haematol	100006	0219QuilichiniID100006.txt	Translocation t(2;19)(p11;p12-p13) in childhood with acute myeloid leukemia	12-2002	Benoit Quilichini, Helene Zattara, Elodie Cas, Laure-Anne Bastide-Alliez, Annie Blachere, Catherine Curtillet, Chantal Fossat, Gérard Michel	Quilichini B, Zattara H, Cas E, Bastide-Alliez LA, Blachere A, Curtillet C, Fossat C, Michel G	Cytogenetic Oncology Laboratory Timone 264, rue Saint-Pierre 13385 Marseille cedex 5, France; Tel : +33-491387402 - Fax : +33-491384663 e-mail : Helene.Cannoni@mail.ap-hm.fr, Benoit.Quilichini@mail.ap-hm.fr	No preleukemia.	No previous solid tumors.		11 yrs	F	Blasts were myeloperoxydase positive, butyrate acetate negative expressing CD 34, CD 33, CD 13, CD 64, CD 7 and HLA DR.	Diagnosis of acute myeloid leukemia with multilineage dysplasia (WHO classification) subtype LAM- M2 (FAB classification).	 46, XX, t(2;19)(p11;p12-13) [30] / 46, XX [10]
Atlas Genet Cytogenet Oncol Haematol	100015	02RocheID100015.txt	Isolated trisomy 2 is non-random and may be found in myelodysplastic syndrome and in acute myeloblastic leukaemia. Case 1	09-2006	Catherine Roche-Lestienne, Agnès Charpentier, Sandrine Geffroy, Joris Andrieux, Jean-Loup Demory, Jean-Luc Laï	Roche-Lestienne C, Charpentier A, Geffroy S, Andrieux J, Demory JL, Laï JL	(1) : Laboratoire de Génétique Médicale, Hôpital Jeanne de Flandre - CHRU de Lille, France; (2) : Département d'Hématologie, Université Catholique de Lille, France; (3) : Laboratoire d'Hématologie A, Hôpital Calmette - CHRU de Lille, France	+	-	-	58 yrs	M		MDS: refractory cytopenia with multilineage dysplasia.	 46,XY, [6]/ 47, XY, +2 [14]
Atlas Genet Cytogenet Oncol Haematol	100016	02RocheID100016.txt	Isolated trisomy 2 is non-random and may be found in myelodysplastic syndrome and in acute myeloblastic leukaemia. Case 2	09-2006	Catherine Roche-Lestienne, Agnès Charpentier, Sandrine Geffroy, Joris Andrieux, Jean-Loup Demory, Jean-Luc Laï	Roche-Lestienne C, Charpentier A, Geffroy S, Andrieux J, Demory JL, Laï JL	(1) : Laboratoire de Génétique Médicale, Hôpital Jeanne de Flandre - CHRU de Lille, France; (2) : Département d'Hématologie, Université Catholique de Lille, France; (3) : Laboratoire d'Hématologie A, Hôpital Calmette - CHRU de Lille, France	-	-	-	69 yrs	F	CD34+,CD13+, CD33+ HLA-DR+, CD14-,CD15-, CD19-, CD10-, CD2-.	AML-M1	 46,XX, [4]/ 47, XX,+2 [18]
Atlas Genet Cytogenet Oncol Haematol	100026	0304ZamecnikovaID100026.txt	t(3;4)(p21;q34) as a sole anomaly in acute myeloid leukemia patient	05-2007	Adriana Zamecnikova	Zamecnikova A	Kuwait Cancer Control Center, Laboratory of Cancer Genetics, Department of Hematology, Shuwaikh, 70653 Kuwait	-	-	-	32 yrs	M	Positive for CD 34, HLDR, CD33, CD34, CD68, myeloperoxidase.	Acute Myeloid Leukemia, M1.	 46,XY,t(3;4)(p21;q34)
Atlas Genet Cytogenet Oncol Haematol	100025	0305ZamecnikovaID100025.txt	t(3;5)(q25;q35) as a sole anomaly in acute myeloid leukemia patient	05-2007	Adriana Zamecnikova	Zamecnikova A	Kuwait Cancer Control Center, Lab of Cancer Genetics, Department of Hem, Shuwaikh, POBox 42262, Shuwaikh, 70653 Kuwait	-	-	-	36 yrs	F	Not available.	Acute Myeloid Leukemia, M2.	 46,XY,t(3;5)(q25;q35)
Atlas Genet Cytogenet Oncol Haematol	100042	0307ReindlID100042.txt	t(3;7)(q26;q21) as a secondary abnormality in MDS RAEB-2	08-2009	Lena Reindl, Claudia Haferlach	Reindl L, Haferlach C	MLL, Munich Leukemia Laboratory, Max-Lebsche-Platz 31, Germany	-	-	-	72 yrs	M	12% myeloid blasts CD33+, CD117+; 31% hypogranulated granuloyctes; 11% monocytes CD56+.		 46,XY,del(20)(q11) [2]/46,XY,idem, t(3;7)(q26;q21)[14].
Atlas Genet Cytogenet Oncol Haematol	100023	0412DalCinID100023.txt	A t(4;12)(q11;p13) in a patient with coincident CLL at the same time of AML diagnosis	05-2007	Paola Dal Cin, Daniel J DeAngelo, Richard M Stone	Dal Cin P, DeAngelo DJ, Stone RM	(PDC) Department of Pathology, Brigham and Women¼s Hospital ; (DJD, RMS) Department of Adult Oncology, Dana-Farber Cancer Institute, Boston, MA	-	-, but coincident CLL at the same time of AML diagnosis. No prior therapy for CLL	-	56 yrs	M	A population of immature cells positive for CD45(dim), HLA-DR, CD7, CD34 (majority) and myeloid markers CD33 and CD13, with absence of staining for B cell, monocytic, and other T cell markers, consistent with myeloblast. A minor clonal kappa positive (moderate intensity) population of CD5 positive B cells which were negative for CD23 was also detected, suggesting a co-existing CD5 positive B cell lymphoproliferative disorder. A minor population of CD19 positive B cells co-expresses CD5 and exhibits monotypic surface immunoglobulin kappa light chain staining, consistent with involvement by the patient's known B cell lymphoproliferative disorder.	Acute Myelogenous Leukemia and Chronic Lymphocytic Leukemia	 46,XY,t(4;12)(q11-12;p13)[18]/46,XY[2]
Atlas Genet Cytogenet Oncol Haematol	100005	0412MooreID100005.txt	The rare t(4;12)(q11;p13) in an elderly patient with de novo AML with multilineage dysplasia co-expressing stem cell markers	08-2002	Sarah Moore, Sanjeev Chunilal, Jacqueline Beerworth	Moore S, Chunilal S, Beerworth J	(1)SA Cancer Cytogenetic Unit, Institute of Medical & veterinary Science, Adelaide, South Australia ; (2)Department of Haematology, The Queen Elizabeth Hospital, Adelaide, South Australia ; e-MAIL sarah.moore@imvs.sa.gov.au	-	-	-	84 yrs	F	CD13+, CD33+, CD7+, CD34+, CD117+, HLA-DR+	de novo AML with multilineage dysplasia	 46,XX,t(4;12)(q11;p13)[15]/46,XX[5]
Atlas Genet Cytogenet Oncol Haematol	100014	0412RaultID100014.txt	t(4;12)(q11;p13) in an acute myeloid leukemia without maturation with myelodysplasia	09-2005	Jean Philippe Rault	Rault JP	CHR Bon Secours GÈnÈtique	-	-	-	67 yrs	M	CD34 (85%), HLA DR (91%) and myeloid cluster: CD11c (7%), CD13 (97%), CD13c (99%), CD33 (98%), CD117 (81%), MPO 5% and only one lymphoid cluster CD7 (87%). Conclusion: immature myeloid population. Phenotype FAB M0	AML type Mo with myelodysplasia	 46, XY, t(4;12)(q11;p13.1) [27] / 46, XY [3]
Atlas Genet Cytogenet Oncol Haematol	100019	0510ReidID100019.txt	A case of myeloproliferative disorder with t(5;10)(q33;q21.2)	12-2006	Valeria AS De Melo, Alistair G Reid	De Melo VAS, Reid AG	Leukaemia Cytogenetics Unit, G Block Room G124, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK				48 yrs	M		Myeloproliferative disorder	 46,XY,t(5;10)(q33;q21.2)[16]/46,XY[8]
Atlas Genet Cytogenet Oncol Haematol	100039	0517RodriguesID100039.txt	Translocation t(5;17)(q13;q21) as the sole cytogenetic anomaly in acute myeloid leukemia after chemotherapy and allogeneic bone marrow transplantation for AML-M4: a case report	08-2008	Elvira D Rodrigues Pereira Velloso, Cristina A Ratis, Edi Cabral, Denize Gonsalez, Nydia S Bacal, Cristóvão LP Mangueira	Rodrigues Pereira Velloso ED, Ratis CA, Cabral E, Gonsalez D, Bacal NS, Mangueira CLP	Clinical Laboratory, Hospital Israelita Albert Einstein, São Paulo, Brazil (EDRPV, CAR, NSB, CLPM); Hospital Santa Cruz, São Paulo, Brazil (ED, DG)	-	+ AML in April, 2005, characterized as AML-M4 (FAB classification), BM cytogenetics with no clonal anomaly (46,XX[12]), immunophenotyping of blast cells showed positivity for CD34, HLA-DR,CD117, cMPO, CD33, CD13, CD4, CD15, CD64 and CD71. The patient was treated with Idarubicin for 3 days, and Ara-C for 7 days, with complete remission. Consolidation chemotherapy with HDARA-C was done. In September, 2005 a full-matched related bone marrow transplantation was performed, from her brother. Karyotypes performed in April and September, 2006 and September, 2007 showed a complete chimerism (//46,XY[20]).	-	40 yrs	F	blast cells positivity for: CD34, HLA-DR,CD117, cMPO, CD33, CD13, CD4, CD15, CD64 and CD71.	AML-M4 in first relapse after allogeneic BMT.	 46,XX, (5;17)(q13;q21)[20]//
Atlas Genet Cytogenet Oncol Haematol	100020	0614AdhvaryuID100020.txt	A novel chromosomal translocation (6;14) (p22;q32) in a case of precursor B-cell Acute Lymphoblastic Leukemia	01-2007	Siddharth G Adhvaryu, Alka Dwivedi, Peggy Stoll	Adhvaryu SG, Dwivedi A, Stoll P	University of Texas Health Science Center at San Antonio, San Antonio, Texas-78229	-	-	-	25 yrs	M	Flow cytometric analysis of the marrow was performed at the Methodist Hospital. The blasts had a precursor B-lymphoblast phenotype: CD19 positive, CD20 positive, CD10 positive, CD79a positive (cytoplasmic) and TdT positive. Myeloid markers (CD13, CD33, CD14, CD117 and myeloperoxidase) are negative. T-cell markers (CD3, CD5, CD7, CD4 and CD8) are also negative. CD34 is positive (partial).	Precursor B-cell Acute Lymphoblastic Leukemia	 46-47, XY,del(5)(q34),t(6;14) (p22;q32),i(9)(q10),del(17)(p10),-20,+mar[cp6]
Atlas Genet Cytogenet Oncol Haematol	100033	0614AdhvaryuID100033.txt	A case of Chronic Lymphocytic Leukemia (CLL) with a rare chromosome abnormality: t(1;14;6)(q21;q32;p21), a variant of t(6;14)(p21;q32).	08-2007	Alka Dwivedi, Thomas Casey, Siddharth G Adhvaryu	Dwivedi A, Casey T, Adhvaryu SG	Cinical and Molecular Cytogenetics Laboratory, Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229-3900, USA (AD)(SGA); Brooke Army Medical Center, Fort Sam Huston, San Antonio, Texas, USA (TC)	-	-	-	57 yrs	F	Bone marrow 05/09/07: CD5+, CD19+, CD20+(dim), CD22+(very dim), CD23+, CD38+, HLA-DR+, surface lambda+(dim), ZAP-70+, CD10-. Matutes score =4 of 5.	Chronic lymphocytic leukemia/Small lymphocytic lymphoma.	 46,XX,t(8;10)(p21;q22)c[16]/46,idem,t(1;14;6)(q21;q32;p21),-6,-12,+1-2mar [4]
Atlas Genet Cytogenet Oncol Haematol	100032	0709LaffinID100032.txt	Translocation t(7;9)(q34;q32) found in pediatric T-cell Acute Lymphoblastic Leukemia	09-2007	Jennifer JS Laffin, Randee J Blumer, Sara J Morrison-Delap, Elizabeth A Rauch, Eric B Johnson, Carol A Diamond, Kate J Thompson, Gordana Raca, Karen D Montgomery, Daniel F Kurtycz	Laffin JJS, Blumer RJ, Morrison-Delap SJ, Rauch EA, Johnson EB, Diamond CA, Thompson KJ, Raca G, Montgomery KD, Kurtycz DF	University of Wisconsin-Madison, School of Medicine and Public Health, Department of Pediatrics, University of Wisconsin Cytogenetic Services, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (JJSL)(CAD); University of Wisconsin Cytogenetic Services, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (RJB)(SJMD)(EAR)(EBJ)(KJT); University of Wisconsin-Madison, School of Medicine and Public Health, Department of Pathology and Laboratory Medicine, University of Wisconsin Cytogenetic Services, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (GR)(KDM)(DFK)	-	-	-	4 yrs	F	NK+, CD2, CD3, CD4, CD5, CD7, CD8, and TdT+	Acute Lymphoblastic Leukemia, L2	 46,XX,t(7;9)(q34;q31~q32)[16]/46,XX[4]
Atlas Genet Cytogenet Oncol Haematol	100029	0812GallegoID100029.txt	Translocation t(8;12)(q13;p13) in a case with acute leukemia of ambiguous lineage	08-2007	Marta Gallego, Mariela Coccé, Andrea Bernasconi, Maria Felice, Cristina Alonso, Myriam Guitter	Gallego M, Coccé M, Bernasconi A, Felice M, Alonso C, Guitter M	Laboratorio de Citogenetica ’Äì Servicio de Genetica-Servicio de Inmunologia - Servicio de Hemato-Oncologia. Hospital de Pediatria SAMIC "Prof. Dr. J. P. Garrahan", Buenos Aires, Argentina	-	-	-	2	F	Blast cells were positive for T linage antigens: CD2, CD7, cCD3; B linage antigens: CD19 and cCD79a and myeloid antigens: CD13 and CD33. A minor (10%) myeloid blast population was also detected among the leukemic cells expressing MPO and CD117. Other positive markers were CD45, CD34, HLA-DR whereas CD10 and TdT were negative.	acute leukemia of ambiguous lineage	 46,XX,t(8;12)(q13;p13)[16]/46,XX[4].
Atlas Genet Cytogenet Oncol Haematol	100018	0813ReidID100018.txt	t(8;13)(p12;q12) in an atypical chronic myeloid leukaemia case	12-2006	Valeria AS De Melo, Alistair G Reid	De Melo VAS, Reid AG	Leukaemia Cytogenetics Unit, G Block Room G124, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK				43 yrs	M		Atypical chronic myeloid leukaemia	 46,XY,t(8;13)(p12;q12)[8]/46,XY[2]
Atlas Genet Cytogenet Oncol Haematol	100027	08LaffinID100027.txt	inv(8)(p11.2q13) found in a patient with chronic myelomonocytic leukemia that progressed to acute myeloid leukemia	02-2007	Jennifer JS Laffin, Sara J Morrison-Delap, Wayne A Bottner, Eric B Johnson, Patricia Howard-Peebles, Kate J Thompson, Gordana Raca, Karen D Montgomery, Daniel F Kurtycz	Laffin JJS, Morrison-Delap SJ, Bottner WA, Johnson EB, Howard-Peebles P, Thompson KJ, Raca G, Montgomery KD, Kurtycz DF	University of Wisconsin-Madison, School of Medicine and Public Health, Department of Pediatrics, University of Wisconsin Cytogenetic Services, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (JJSL); University of Wisconsin Cytogenetic Services, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (SJMD) (EBJ) (KJT); Gundersen Lutheran Medical Center, La Crosse, WI, USA (WAB); University of Wisconsin-Madison, School of Medicine and Public Health, Department of Pathology and Laboratory Medicine, University of Wisconsin Cytogenetic Services, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (PHP) (GR) (KDM) (DFK)	+	-	-	67 yrs	M	Negative for: CD34, CD2, CD3, CD19, CD20, TdT, cyto CD3, CD7	AML, M4	 46,XY,inv(8)(p11.2q13)[6]/46,XY[14]
Atlas Genet Cytogenet Oncol Haematol	100009	0X20ReddyID100009.txt	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 1	01-2005	Kavita S. Reddy, Kathy Richkind	Reddy KS, Richkind KE	Genzyme Genetics, Orange, CA. Kavita.reddy@gmail.com	-	Breast infiltrating ductal carcinoma treated with radiation and tamoxifen.		57 yrs	F		Myelodysplastic syndrome (MDS): refractory anaemia	 46,X,t(X;20)(q13;q13.3)[5]/46,XX[15]
Atlas Genet Cytogenet Oncol Haematol	100010	0X20ReddyID100010.txt	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 2	01-2005	Kavita S Reddy, Kathy Richkind	Reddy KS, Richkind KE	Genzyme Genetics, Orange, CA. Kavita.reddy@gmail.com	Myelofibrosis	A low-grade lobular and ductal carcinoma with a small percentage of intraductal breast disease treated with tamoxifen.		61 yrs	F		Myelofibrosis -> acute leukemia	 46,X,t(X;20)(q13;q13.3),der(1;7)(q10;p10)[20]/46,XX[1]
Atlas Genet Cytogenet Oncol Haematol	100011	0X20ReddyID100011.txt	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 3	01-2005	Kavita S Reddy, Kathy Richkind	Reddy KS, Richkind KE	Genzyme Genetics, Orange, CA. Kavita.reddy@gmail.com	-	No clinical information		77 yrs	F		Myelodysplastic syndrome (MDS): sideroblastic anemia	 46,X,t(X;20)(q13;q13.3)[10]/46,XX[10]
Atlas Genet Cytogenet Oncol Haematol	100012	0X20ReddyID100012.txt	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 4	01-2005	Kavita S Reddy, Kathy Richkind	Reddy KS, Richkind KE	Genzyme Genetics, Orange, CA. Kavita.reddy@gmail.com	-	No clinical information		66 yrs	F		Myelodysplastic syndrome (MDS): pancytopenia and thrombocytopenia	 46,X,t(X;20)(q13;q13.3)[3].ish t(X;20)(q11.2-12;q13.3) (wcpX+, wcp20+, AR_; wcp20+, D20S108+, AR+, wcpX+)/46,XX[18]
Atlas Genet Cytogenet Oncol Haematol	100034	1115RodriguesID100034.txt	Translocation t(11;15)(q23;q14) detected in AML at first relapse	04-2008	Elvira D Rodrigues Pereira Velloso, Silvia Helena Figueiredo, Cristina A Ratis, Ana Cláudia Brito, Nydia S Bacal, Yana AS Novis, Cristóvão LP Mangueira	Rodrigues Pereira Velloso ED, Figueiredo SH, Ratis CA, Brito AC, Bacal NS, Novis YAS, Mangueira CLP	Laboratorio clínico Hospital Israelita Albert Einstein, Av. Albert Einstein, 627/701 - Morumbi - Sao Paulo, Brazil (EDRPV, SHF, CAR, ACB, NSB, CLPM); Hospital Sirio Libanes, Sao Paulo, Brazil (YASN)	-	+ 17 months before (September, 2006) an AML-M6 "de novo" (FAB) was diagnosed. Immunophenotype study showed expression of CD117,CD34, HLA-DR, CD33, CD13, CD71, CD38, CD36 and CD11c, Bone Marrow karyotype showed clonal trisomy 21 (47,XY,+21[2]/46,XY[13]). The treatment included chemotherapy induction cycle with Idarrubicin and Ara-C (3+7) and consolidation with HDDAC. In April, 2007 a hematologic and immunophenotypic remission was observed, although a karyotype showed one methaphase with trisomies 13 and 21 (48,XY,+13,+21[1]/46,XY[19]. In October, 2007, cytometry and cytogenetic bone marrow studies showed complete remission.	-	30 years	M	CD 45+ gate: CD117, CD34, HLA-DR, CD33, CD13, CD71, CD38, CD36, CD11c and cMPO.	AML in first relapse.	 46,XY,t(11;15)(q23;q14)[20]
Atlas Genet Cytogenet Oncol Haematol	100028	1120GangulyID100028.txt	Translocation t(11;20)(p15;q11) detected in AML M0: A case report	04-2007	Bani B Ganguly, Yogesh Loher, M B Agarwal	Ganguly BB, Loher Y, Agarwal MB	MGM Centre for Genetic Research and Diagnosis, MGM's New Bombay Hospital, Navi Mumbai, India (BBG); Hemato-oncology Department, Bombay Hospital and Research Centre, Mumbai, India (YL) (MBA)	-	-	-	28 yrs	F	Positive for CD13, CD33 and CD117	AML-M0 (FAB)	 46,XX,t(11;20)(p15;q11) [100%, 24/24 cell]
Atlas Genet Cytogenet Oncol Haematol	100031	1621BradtkeID100031.txt	A case of trisomy 8 and loss of the Y-chromosome as secondary aberrations in a ten year old boy with de novo AML FAB M2 and t(16;21)(q24;q22)	11-2007	Jutta Bradtke, Peter Vorwerk, Jochen Harbott	Bradtke J, Vorwerk P, Harbott J	Dipl.-Biol., Fachhumangenetikerin GfH, Oncogenetic Laboratory, Dept. Ped. Hematology / Oncology, Schlangenzahl 14, 35385 Giessen, Germany (JB)	-	-	-	10 yrs	M	CD13+, CD33+	ANLL M2	 46,X,-Y,+8,t(16;21)(q24;q22)
Atlas Genet Cytogenet Oncol Haematol	100013	1621BruyereID100013.txt	A new case of t(16;21)(q24;q22) in a secondary AML-M2 following breast cancer therapy	08-2005	Helene Bruyere, Wilson Yeung, Peter Tsang	Bruyere H, Yeung W, Tsang P	Department of Pathology and Laboratory Medicine, Vancouver General Hospital, UBC, Canada, Helene.Bruyere@vch.ca and Division of Hematology, Vancouver General Hospital, UBC, Canada	-	Breast cancer diagnosed in 2002, treated with radical mastectomy, chemotherapy with cyclophosphamide, epirubicin, 5-fluoro-uracil, radiotherapy.	-	61 yrs	F	Positive for HLA-DR, CD34, CD117, CD13, CD33, MPO, CD56 and CD19 ; Partial Tdt ; Negative for CD7	Hypoplastic AML, therapy related	 47,XX,+8,t(16;21)(q24;q22)[13]/46,XX[3]
Atlas Genet Cytogenet Oncol Haematol	100022	1621DalCinID100022.txt	t(16;21)(q24;q22) in therapy-related acute myelogenous leukemia arising from myelodysplastic syndrome	02-2007	Paola Dal Cin, Karim Ouahchi	Dal Cin P, Ouahchi K	Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA	+ RAEB diagnosed in 09-2006	+ Hodgkin's lymphoma diagnosed in 2003		32 yrs	M	Population of immature cells is positive for CD34 +, CD45 (dim), HLA-DR +, CD117 +, CD13 +, and CD33+ and negative for CD15-, monocytic, B and T lymphoid markers.		 49,XY,+Y,+3,+8,t(16;21)(q24;q22)[18]/46,XY[2]
Atlas Genet Cytogenet Oncol Haematol	100004	21CRRoyID100004.txt	Pentasomy 21 as a sole abnormality in an atypical CML patient in chronic phase	04-2002	Shambhu K Roy, Sonal R Bakshi, Shailesh J Patel, Pina J Trivedi, Manisha M Brahmbhatt, Shwetal M Rawal, Pankaj M Shah, Devendra D Patel	Roy SK, Bakshi SR, Patel SJ, Trivedi PJ, Brahmbhatt MM, Rawal SM, Shah PM, Patel DD	: Cell Biology Division, Medical Oncology Department1, Director2, The Gujarat cancer & Research Institute, NCH Campus, Asarwa, Ahmedabad-380016, India. (gcriad1@sancharnet.in)	-	-	-	65 yrs	F		Atypical CML chronic phase	 49XX,+21, +21, +21. (Pentasomy 21) in all 20 karyotypes (Fig 1).
Atlas Genet Cytogenet Oncol Haematol	100007	814QuilichiniID100007.txt	A new case of t(8;14)(q11;q32) in an acute lymphoblastic leukemia	05-2003	Benoit Quilichini, Helene Zattara, François Casalonga, Laure-Anne Bastide-Alliez, Catherine Curtillet, Chantal Fossat, Gérard Michel	Quilichini B, Zattara H, Casalonga F, Bastide-Alliez LA, Curtillet C, Fossat C, Michel G	Cytogenetic Oncology Laboratory : CHU Timone 264, rue Saint-Pierre 13385 Marseille cedex 5, France ; Tel : +33-491387402 • Fax : +33-491384663 e-mail : Helene.Cannoni@mail.ap-hm.fr, Benoit.Quilichini@mail.ap-hm.fr	-	-	-	13 yrs	M	HLA DR+ (high), CD34+ (high), CD10+ (low), CD19+ (high), c mu -, CD79a+ (high). Blasts were myeloperoxydase negative.	Diagnosis of precursor B-cell acute lymphoblastic leukemia (WHO classification), LAL-B II (EGIL classification).	 45, X, - Y, t(8;14)(q11;q32) [ 16 ] / 46, XY [ 4 ]
Atlas Genet Cytogenet Oncol Haematol	100044	der0918XuID100044.txt	Unbalanced rearrangement der(9;18)(p10;q10) in a patient with polycythemia vera	04-2010	Xinjie Xu, Xueyan Chen, Elizabeth A Rauch, Eric B Johnson, Kate J Thompson, Jennifer JS Laffin, Gordana Raca, Daniel F Kurtycz	Xu X, Chen X, Rauch EA, Johnson EB, Thompson KJ, Laffin JJS, Raca G, Kurtycz DF	University of Wisconsin-Madison, School of Medicine and Public Health, Department of Pediatrics, University of Wisconsin Cytogenetic Services, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (XX, JJSL); University of Wisconsin-Madison, Department of Pathology and Laboratory Medicine, Madison, WI, USA (XC); University of Wisconsin Cytogenetic Services, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (EAR, EBJ, KJT); University of Wisconsin-Madison, School of Medicine and Public Health, Department of Pathology and Laboratory Medicine, University of Wisconsin Cytogenetic Services, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (GR); University of Wisconsin-Madison, School of Medicine and Public Health, Department of Pathology and Laboratory Medicine, Wisconsin State Laboratory of Hygiene, Madison, WI, USA (DFK)	-	-	-	69 yrs	F	NA	Polycythemia vera	 46,XX,+9,der(9;18)(p10;q10)[11]/46,XX[9]
Atlas Genet Cytogenet Oncol Haematol	100052	der918Case1ReddyID100052.txt	Unbalanced rearrangement, der(9;18)(p10;q10) in a patient with myeloproliferative neoplasm. Case 0001M.	03-2011	Kavita S Reddy	Reddy KS	Kaiser Permanente Southern California, 4580 ElectronicPlace, Los Angeles, CA 90039, USA	+	-	-	71 yrs	M	NA	CMPN	 10/2004 BM 46,XY[20]; 6/2007 PB 46,XY[10]; 12/2010 BM 46,XY,+9,der(9;18)(p10;q10)[8]/46,sl,del(13)(q12q14)[cp6]/46,XY[6]
Atlas Genet Cytogenet Oncol Haematol	100053	der918Case2ReddyID100053.txt	Unbalanced rearrangement, der(9;18)(p10;q10) in a patient with myelodysplastic syndrome. Case 0002M.	03-2011	Kavita S Reddy	Reddy KS	Kaiser Permanente Southern California, 4580 ElectronicPlace, Los Angeles, CA 90039, USA	+	+ Bladder cancer, status post removal and BCG treatment	-	85 yrs	M	NA	MDS	 3/2005 BM 45,X,-Y[5]/46,XY,+9,der(9;18)(p10;q10)[11]/46,XY[4]; 6/2007 BM 45,X,-Y[5][4]/46,XY[16]; 12/2010 BM 46,XY,+9, der(9;18)(p10;q10)[15]/46,XY[5]
Atlas Genet Cytogenet Oncol Haematol	100057	der918p10q10CambosuID100057.txt	Unbalanced rearrangement der(9;18)(p10;q10) and JAK2 V617F mutation in a patient with AML following post-polycythemic myelofibrosis	09-2011	Francesca Cambosu, Giuseppina Fogu, Paola Maria Campus, Claudio Fozza, Luigi Podda, Andrea Montella, Maurizio Longinotti	Cambosu F, Fogu G, Campus PM, Fozza C, Podda L, Montella A, Longinotti M	Clinical Genetics, Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/B 07100 Sassari, Italy (FC, GF, AM); Azienda Ospedaliero-Universitaria Sassari, Italy (PMC, CF, LP, AM, ML); Institute of Hematology, University of Sassari, Italy (CF, LP, ML)	-	-	-	66 yrs	M	NA	Polycythemia vera. Myelofibrosis: hypocellular bone marrow with marked increase in reticulin fibres. AML M2.	 46,XY, +9,der(9;18)(p10;q10) in 25/25 cells scored.
Atlas Genet Cytogenet Oncol Haematol	100043	dic0709RodriguesID100043.txt	Dicentric dic(7;9)(p11;p11): a new case in childhood ALL	09-2009	Elvira D Rodrigues Pereira Velloso, Carolina Kassab, Silvia Helena A Figueira, Denise Tiemi Noguchi, Eliana Carla Armelin Benites, Cristóvão L P Mangueira, Fábio Morato de Oliveira	Rodrigues Pereira Velloso ED, Kassab C, Figueira SHA, Noguchi DT, Armelin Benites EC, Mangueira CLP, de Oliveira FM	Clinical Laboratory, Hospital Israelita Albert Einstein, Sao Paulo, Brazil (EDRPV, CK, SHAF, CLPM); Instituto de Clinicas Pediatricas Bolivar Risso - GRENDACC, Sao Paulo, Brazil (DTN, ECAB); Cytogenetics and Onco-Hematology, FMRP USP, Brazil (FMDO)	-	-	-	13 yrs	F	Blast cells positivity for: CD 34, HLA, CD10, CD19, CD22 and cCD79a.	Common B (B-II) ALL at diagnosis.	 45,XX,-7,+mar[11]/45,XX,dic(7;9)(p11;p11)[9]/46,XX[4]
Atlas Genet Cytogenet Oncol Haematol	100035	dic115inaMPDRocheID100035.txt	Dic(1;15)(p11;p11) as a non-random abnormality in atypical MPD	05-2008	Olivier Theisen, Steven Richebourg, Jean-Luc Lai, Catherine Roche-Lestienne	Theisen O, Richebourg S, Lai JL, Roche-Lestienne C	Laboratoire de Genetique Medicale, Hopital Jeanne de Flandre, CHRU de Lille, France (OT, SR, JLL, CRL); Institut de Recherche sur le Cancer, Centre JP Aubert, Unite Inserm 837, Lille, France (JLL, CRL)	-	-	-	59 yrs	F	-	Atypical myeloproliferative disease, presenting polycythemia and thrombocythemia with myelofibrosis.	 47,XX,+9,-15,+dic(1;15)(p11;p11)[20]
Atlas Genet Cytogenet Oncol Haematol	100036	dic115inETRocheID100036.txt	Dic(1;15)(p11;p11) as a non-random abnormality in essential thrombocytemia	05-2008	Olivier Theisen, Steven Richebourg, Jean-Luc Lai, Catherine Roche-Lestienne	Theisen O, Richebourg S, Lai JL, Roche-Lestienne C	Laboratoire de Genetique Medicale, Hopital Jeanne de Flandre, CHRU de Lille, France (OT, SR, JLL, CRL); Institut de Recherche sur le Cancer, Centre JP Aubert, Unite Inserm 837, Lille, France (JLL, CRL)	-	-	-	74 yrs	F	-	Essential Thrombocytemia	 46,XX,[3]/46,XX,-15,+dic(1;15)(p11;p11)[10]
Atlas Genet Cytogenet Oncol Haematol	100037	dic115inMyelodRocheID100037.txt	Dic(1;15)(p11;p11) as a non-random abnormality in Myelodysplasic syndrome	05-2008	Olivier Theisen, Steven Richebourg, Jean-Luc Lai, Catherine Roche-Lestienne	Theisen O, Richebourg S, Lai JL, Roche-Lestienne C	Laboratoire de Genetique Medicale, Hopital Jeanne de Flandre, CHRU de Lille, France (OT, SR, JLL, CRL); Institut de Recherche sur le Cancer, Centre JP Aubert, Unite Inserm 837, Lille, France (JLL, CRL)	-	-	-	76	F	-	myelodysplastic syndrome (MDS): refractory anemia with ringed sideroblast (RARS)	 46,XX,[3]/47,XX,+8[3]/47,XX,+8,-15,+dic(1;15)(p11;p11)[8]
Atlas Genet Cytogenet Oncol Haematol	100038	dic115inPVRocheID100038.txt	Dic(1;15)(p11;p11) as a non-random abnormality in Polycytemia Vera	05-2008	Olivier Theisen, Steven Richebourg, Jean-Luc Lai, Catherine Roche-Lestienne	Theisen O, Richebourg S, Lai JL, Roche-Lestienne C	Laboratoire de Genetique Medicale, Hopital Jeanne de Flandre, CHRU de Lille, France (OT, SR, JLL, CRL); Institut de Recherche sur le Cancer, Centre JP Aubert, Unite Inserm 837, Lille, France (JLL, CRL)	-	-	-	72 yrs	F	-	Polycytemia vera.	 46,XX,-15,+dic(1;15)[13]
Atlas Genet Cytogenet Oncol Haematol	100062	dic115p11p11VellosoID100062.txt	A new case of dic(1;15) in essential thrombocythaemia with JAK2 V617F mutation	02-2012	Elvira D Rodrigues Pereira Velloso, Cristina Alonso Ratis, Renata Kiyomi Kishimoto, Daniel Aquilino Oliveira, Nádia Cristina de Sousa Misael, João Carlos de Campos Guerra, Cristóvão Luis P Mangueira	Rodrigues Pereira Velloso ED, Alonso Ratis C, Kishimoto RK, Aquilino Oliveira D, de Sousa Misael NC, de Campos Guerra JC, Mangueira CLP	Laboratorio de Tecnicas Especiais- Citogenetica do Hospital Israelita Albert Einstein, Sao Paulo, Brazil (EDRPV, CAR, RKK, DAO, NCdSM, CLPM); Centro de Hematologia, Sao Paulo, Brazil (JCdCG)	+ Essential thrombocythaemia diagnosed in 2000 with normal karyotype and treated from 2003 to 2010 with low doses of Myleran	-	-	78 yrs	F		Essential thrombocythaemia with JAK2 V617F mutation	 46,XX,+15,dic(1;15)(p11;p11)[10]/46,XX[10]
Atlas Genet Cytogenet Oncol Haematol	100058	ins16q22p13p13MohamID100058.txt	Insertion as an alternative mechanism of CBFB-MYH11 gene fusion in a new case of acute myeloid leukemia with an abnormal chromosome 16	10-2011	Yaser Hussein, Vandana Kulkarni, Anwar N Mohamed	Hussein Y, Kulkarni V, Mohamed AN	Cytogenetics Laboratory, Pathology Department, Wayne State University School of Medicine, Detroit Medical Center, Detroit MI, USA	-	-	+ Thalassemia trait carrier	17 yrs	F	Flow cytometry of bone marrow aspirate identified a significant population of myeloblasts (49%) expressing CD34, HLA-DR, CD9, CD13, CD33, CD117 and partially expressing CD15, CD11b, and CD64. A second population of monocytes is also identified (37%) expressing CD4, CD14, CD15, CD36 and CD64.	Acute myelomonocytic leukemia with abnormal eosinophils (AML-M4eos) and CBFB/16q22 rearrangement.	 At time of diagnosis abnormal metaphase cells with the following karyotype was found; 46,XX,ins(16)(q22p13p13)[20] (see Figure 1). Remission bone marrow on 4/20/2011 and 9/13/2011 revealed a normal female karyotype; 46,XX[20].
Atlas Genet Cytogenet Oncol Haematol	100045	MLLMohamedID100045.txt	Amplification of MLL gene in a new case of acute myeloid leukemia	05-2010	Sayf Alkatib, Deborah Schloff, Anwar N Mohamed	Alkatib S, Schloff D, Mohamed AN	Cytogenetics Laboratory, Pathology Department, Wayne State University School of Medicine, Detroit Medical Center, Detroit MI, USA	-	-	-	75 yrs	F	Flow cytometry identified a population of blasts of myeloid origin encompassing 31% of cells. The blasts were expressing CD13, CD33, CD34, CD117, HLA-DR, and CD56.	Acute myeloid leukemia with multilineage dysplasia.	 Analysis of 20 metaphase cells revealed an abnormal female karyotype in all metaphases. Very complex chromosomal abnormalities were identified. karyotype was designated; 45,X,add(X)(q22),-3,del(5)(q13q33),hsr(11)(q23),add(12)(p11.2),-17,+r[cp20].
Atlas Genet Cytogenet Oncol Haematol	100047	t0106VellosoID100047.txt	Chronic lymphocytic leukaemia/Small lymphocytic lymphoma (CLL/SLL) associated with translocation t(1;6)(p35;p25) as part of complex karyotype	08-2010	Elvira D Rodrigues Pereira Velloso, Daniela Borri, Cristina Alonso Ratis, Guilherme Fleury Perin, Nelson Hamerschlak, Nydia S Bacal, Paulo A A Silveira, Alanna M P S Bezerra, Denise C Pasqualin	Rodrigues Pereira Velloso ED, Borri D, Alonso Ratis C, Fleury Perin G, Hamerschlak N, Bacal NS, Silveira PAA, Bezerra AMPS, Pasqualin DC	Clinical Laboratory of Hospital Israelita Albert Einstein, Sao Paulo, Brazil (EDRPV, DB, CAR, NSB, PAAS); Pathology Department of Hospital Israelita Albert Einstein, Sao Paulo, Brazil (AMPSB, DCP); Hematology Department of Hospital Israelita Albert Einstein, Sao Paulo, Brazil (GFP, NH)	-	+ Chronic lymphocytic leukaemia/Small lymphocytic lymphoma (CLL/SLL) diagnosed 19 months earlier, in first relapse after 4 cycles of RFC (Fludarabine, cyclophosphamide and Rituximab)	-	64 yrs	M	Small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL)	Chronic lymphocytic leukaemia/Small lymphocytic lymphoma (CLL/SLL) with high Ki-67 index.	 (using ISCN): 44,XY, t(1;6)(p35;p25), der(4)(q21), -9, add(17)(p13), -21, +mar[6]/46,XY[14]
Atlas Genet Cytogenet Oncol Haematol	100046	t0106ZamecnikovaID100046.txt	der(6)t(1;6)(q21;p21) in myelofibrosis following polycythemia vera	07-2010	Adriana Zamecnikova	Zamecnikova A	Kuwait Cancer Control Center, Department of Hematology, Laboratory of Cancer Genetics, Kuwait	-	+	-	78 yrs	F	CD11 95%, CD11c 80%, CD13 100%, CD33 98%, CD15 92%, MPO 82%.	Post polycythemic myelofibrosis.	 PB 46,XX [5]/46,XX,der(6)t(1;6)(q21;p21) [25] ; BM 46,XX,der(6)t(1;6)(q21;p21) [20]
Atlas Genet Cytogenet Oncol Haematol	100051	t0412HeatonID100051.txt	A new case of t(4;12)(q12;p13) in a secondary acute myeloid leukemia with review of literature	03-2011	Sarah M Heaton, Frederick Koppitch, Anwar N Mohamed	Heaton SM, Koppitch F, Mohamed AN	Cytogenetics Laboratory, Pathology Department, Wayne State University School of Medicine, Detroit Medical Center, Detroit MI, USA	-	+ Hodgkin's Lymphoma, stage IVA at age 25 year, treated with ABVD for 12 months. Tumor mass in the upper cervical spine diagnosed at age 27 year, treated with laminectomy and five doses of radiation.	-	57 yrs	M	Flow cytometry (FCM) revealed that the blasts were of myeloid lineage expressing CD13, CD33, CD34, CD117, HLA-DR, and CD56.	Acute myeloid leukemia (AML) with dysplastic changes.	 46,XY,t(4;12)(q12;p13)[6]/46,XX[14] in June 2008 (post transplant)
Atlas Genet Cytogenet Oncol Haematol	100065	t0412q11p13CallahanID100065.txt	Patient with t(4;12)(q11;p13) with therapy-related MDS and known history of stage II metastatic colorectal cancer	09-2012	Elizabeth Callahan, Roger Schultz, Theresa C Brown	Callahan E, Schultz R, Brown TC	CSI Laboratories, 2580 Westside Parkway, Alpharetta, GA 30004, USA (EC, TCB); Signature Genomic Laboratories, Perkin Elmer Inc., Spokane, WA 99207, USA (RS)	-	+ Patient diagnosed with rectal cancer 8/03 treated with surgery and adjuvant chemo and radiation therapy. 9/2008 stage II isolated metastatic colorectal cancer involving the lung. Patient was treated with surgical resection and 5FU therapy and radiation. Patient is currently in remission. Has sibling with renal cell carcinoma.	-	63 yrs	F	CD7: 44.4%, CD13: 67.5%, CD34: 28.7%, CD117: 30.9%, HLA-DR: 38.5%, CD38: 71.4%.	Flow cytometry- Acute myelogenous leukemia with ~29% myeloblasts. Morphology- therapy-related myelodysplasia with 18% blasts.	 46,XX,t(4;12)(q11;p13)[20]
Atlas Genet Cytogenet Oncol Haematol	100059	t1122q23q13MohamedID100059.txt	A case of Acute Lymphoblastic Leukemia with rare t(11;22)(q23;q13)	10-2011	Jill D Kremer, Anwar N Mohamed	Kremer JD, Mohamed AN	Cytogenetics Laboratory, Pathology Department, Wayne State University School of Medicine, Detroit Medical Center, Detroit MI, USA	-	-	+ Patient has hemoglobin S trait	14 mths	M	Flow cytometry of bone marrow aspirate identified a dim CD45 lymphoblast population (85%) expressing HLA-DR, CD19 and partially expressing CD10, CD22, CD9 and CD40.	CD34 negative B-precursor ALL.	 46,Y,der(X)t(X;9)(p11.1;q11),add(9)(q11),t(11;22)(q23;q13)[20] (see Figure 1). Post induction bone marrow study demonstrated a normal 46,XY karyotype.
Atlas Genet Cytogenet Oncol Haematol	100048	t1414BALLVellosoID100048.txt	A new case of translocation t(14;14)(q11;q32) in B lineage ALL	02-2011	Elvira D Rodrigues Pereira Velloso, Priscila Pereira dos Santos Teixeira, Karina Prandi Melillo, Luciana J Rodrigues da Silva, Cristina Alonso Ratis, Daniela Borri, Cristóvão LP Mangueira	Rodrigues Pereira Velloso ED, Pereira dos Santos Teixeira P, Prandi Melillo K, Rodrigues da Silva LJ, Alonso Ratis C, Borri D, Mangueira CLP	Clinical Laboratory, Hospital Israelita Albert Einstein, Sao Paulo, Brazil (EDRPV, PPdST, LJRdS, CAR, DB, CLPM); CASE Intermedica, Sao Paulo, Brazil (KPM)	-	-	-	43 yrs	M	HLA-DR+, TdT+, CD79a+, CD19+, cyCD22+, CD20+, CD10+	common B-ALL	 46,XY,t(14;14)(q11;q32.1)[20]
Atlas Genet Cytogenet Oncol Haematol	100063	t1721q11q22PodgornikID100063.txt	t(17;21)(q11.2;q22) as a sole aberration in acute myelomonocytic leukemia	02-2012	Helena Podgornik, Peter Cernelc	Podgornik H, Cernelc P	University medical center Ljubljana, Department of Haematology, Zaloska 7, 1000 Ljubljana, Slovenia	-	-	-	87 yrs	M	CD4-/CD11c+/CD13+/CD14+/CD15+/CD33+/CD34+↓/CD45+/ CD64+/CD65+/MPO+↓	Acute myelomonocytic leukemia	 46,XY,t(17;21)(q11.2;q22)[19]/46,XY[1]
Atlas Genet Cytogenet Oncol Haematol	100055	t514q31q32GallegoID100055.txt	A new case of t(5;14)(q31;q32) in a pediatric acute lymphoblastic leukemia presenting with hypereosinophilia	09-2011	Marta Gallego, Mariela Coccé, María Felice, Jorge Rossi, Silvia Eandi, Gabriela Sciuccati, Cristina Alonso	Gallego M, Coccé M, Felice M, Rossi J, Eandi S, Sciuccati G, Alonso C	Laboratorio de Citogenetica - Servicio de Genetica - Servicio de Inmunologia y Reumatologia - Servicio de Hemato-Oncologia, Hospital de Pediatria "Prof. Dr. J. P. Garrahan", Buenos Aires, Argentina	+ The patient presented with a chronic eosinophilic leukemia 3 months before developing ALL.	-	-	11 yrs	M	Pre-B ALL (EGIL classification B III). The blasts expressed CD45, CD19, CD10, CD34, HLA-DR, cCD79a, cCD22, Tdt and cytoplasmic micro chain, partial CD20 and CD33 and were negative for CD2, CD7, CD13, CD15, CD117 and CD3.	Acute lymphoblastic leukemia following a chronic eosinophilic leukemia.	 Karyotype at time of diagnosis of ALL: 46,XY,t(5;14)(q31;q32)[4]/46,XY[12]
Atlas Genet Cytogenet Oncol Haematol	100061	t622p21q11DueberID100061.txt	t(6;22)(p21;q11.2) arising at second relapse in a patient with t(8;21)-positive acute myeloid leukemia	11-2011	Julie C Dueber, Aaron C Shaver, Rebecca S Dean, Amy E Gardner, Stephen Strickland, Mary Ann Thompson, Ashwini Yenamandra	Dueber JC, Shaver AC, Dean RS, Gardner AE, Strickland S, Thompson MA, Yenamandra A	Department of Pathology, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN 37232, USA (JCD, ACS, RSD, AEG, MAT, AY); Department of Medicine, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN 37232, USA (SS)	+ The patient was diagnosed with FLT3 negative, NMP1 negative AML in March of 2010. His karyotype at diagnosis was 46,XY, t(8;21)(q22;q22). He was treated with cytarabine and idarubicin for induction and cytarabine and daunorubicin for consolidation. He relapsed in November, 2010 and received mitoxantrone, etoposide, and cytarabine for re-induction. Cytogenetics performed at the time of this first relapse continued to demonstrate t(8;21)(q22;q22) as the sole cytogenetic abnormality. Upon evaluation in April, 2011 for potential stem-cell transplant, the bone marrow biopsy described in this study confirmed that the patient's acute myeloid leukemia had relapsed for a second time.	-	-	60 yrs	M	CD45 dim, CD117+, CD34+, CD13+, CD19-, and CD61+/- myeloblasts.	Hypercellular bone marrow with trilineage hematopoiesis; extensive involvement by acute myeloid leukemia.	 46,XY,t(8;21)(q22;q22)[5]/46,idem,t(6;22)(p21;q11.2)[3]/46,XY[12]
Atlas Genet Cytogenet Oncol Haematol	100060	t68q27p12GindinaID100060.txt	t(6;8)(q27;p12) in a new case "8p11 myeloproliferative syndrome"	11-2011	Tatiana Gindina, Vadim Baykov, Valentina Kravtcova, Ildar Barkhatov, Olga Slesarchuk, Maria Vlasova, Elena Nikolaeva, Varvara Ovechkina	Gindina T, Baykov V, Kravtcova V, Barkhatov I, Slesarchuk O, Vlasova M, Nikolaeva E, Ovechkina V	I.P.Pavlov State Medical University, R.M. Gorbacheva Memorial Institute of Children Hematology and Transplantation, Cytogenetic Laboratory, Saint Petersburg, Russia	-	-	-	19 yrs	F	Not performed.	Myeloid and lymphoid neoplasms with FGFR1 abnormalities.	 Analysis of 20 metaphase cells revealed an abnormal female karyotype in all metaphases. 46,XX,t(6;8)(q27;p12)[20] .
Atlas Genet Cytogenet Oncol Haematol	100064	t721p22q22GindinaID100064.txt	A new case of Acute Myeloid Leukemia with semi-cryptic t(7;21)(p22;q22)	04-2012	Tatiana Gindina, Ildar Barkhatov, Elmira Boychenko, Irina Garbuzova, Maria Vlasova, Elena Nikolaeva, Irina Petrova, Varvara Ovechkina, Tatiana Shorstova	Gindina T, Barkhatov I, Boychenko E, Garbuzova I, Vlasova M, Nikolaeva E, Petrova I, Ovechkina V, Shorstova T	I.P. Pavlov State Medical University, R.M. Gorbacheva Memorial Institute of Children Hematology and Transplantation, Cytogenetic Laboratory, Saint Petersburg, Russia (TG, IB, MV, EN, IP, VO, TS); City Children's Hospital No.1, Saint Petersburg, Russia (EB, IG)	-	-	-	13 yrs	M	Positive for CD45dim, CD33, CD56, CD34, CD7, CD117, CD13, CD71, HLA-DR; additionally, there is abnormal coexpression of CD4 and CD11b.	AML M4 (FAB), AML with multilineage dysplasia (WHO).	 Analysis of 20 metaphase cells revealed an abnormal male karyotype. 46,XY,add(21)(q22)[19]/46,XY,idem,del(5)(q13q31)[1].
Atlas Genet Cytogenet Oncol Haematol	100002	t814BalicekID100002.txt	A case of Down syndrome with acute lymphoblastic leukemia and t(8;14)(q11;q32)	06-2001	Petr Balicek, Jana Rabasova, Jiri Hak	Balicek P, Rabasova J, Hak J	Division of Medical Genetics, University Hospital, 500 05 Hradec Kralove, Czech Republic	-	-	Down syndrome patient	17 yrs	M	CD10 (CALLA) positive; CD66 positive	Early pre-B ALL	 47,XY, der(14)t(8;14)(q11;q32),+21 "c" [17]/47,XY,+21 "c" [3]
Atlas Genet Cytogenet Oncol Haematol	100001	t814KerndrupID100001.txt	A case of pre-B ALL with t(8;14)(q11;q32)	06-2001	Gitte Birk Kerndrup, Steen Rosthøj	Kerndrup GB, Rosthøj S	Institute of Pathology-Chromosome Laboratory, Odense University Hospital, DK-5000 Odense C., Denmark and The Department of Paediatric Oncology, Aalborg Hospital, DK-8000 Aalborg, Denmark	-	-	-	11 yrs	M	CD19+/CD10+/Tdt+	pre-B ALL	 49,XY,+X,t(8;14)(q11;q32),+12,+21[15]/46,XY[10]
Atlas Genet Cytogenet Oncol Haematol	100050	t814q24q32RichebID100050.txt	Translocation t(8;14)(q24;q32) as a clue for the diagnosis of B cell prolymphocytic leukemia	03-2011	Steven Richebourg, Richard Garand, Bruno Villemagne, Celine Bossard, Anne Moreau, Pascaline Talmant	Richebourg S, Garand R, Villemagne B, Bossard C, Moreau A, Talmant P	Laboratoire d'Hematologie, University Hospital, Nantes, France	-	-	-	64 yrs	M	CD19+, CD5+(high),CD23+(low), CD22+(high), CD79b+(high), FMC7+, surface Ig Lambda (high). Matutes score = 2 (CD10-, CD20+ high, CD43-, CD81+ high)	B cell prolymphocytic leukaemia	
Atlas Genet Cytogenet Oncol Haematol	100054	t89p12q33ZengerID100054.txt	Translocation t(8;9)(p12;q33) detected in cALL: A case report	03-2011	Melanie Zenger, Claudia Haferlach	Zenger M, Haferlach C	MLL Munchner Leukamielabor GmbH, Max-Lebsche-Platz 31, 81377 Munchen, Germany	-	-	-	85 yrs	F	Positive for CD10, CD19, HLA-DR, CD34 and cytoplasmatic TdT; CD20 is expressed on 1% of the cells; additionally, there is abnormal coexpression of CD33 and CD13.	cALL	 46,XX,t(8;9)(p12;q33)[14/20]
Atlas Genet Cytogenet Oncol Haematol	100049	tri16tri18ZamecnikID100049.txt	Trisomy 16 and 18 in acute lymphoblastic leukemia patient with ETV6-RUNX1 rearrangement	03-2011	Adriana Zamecnikova	Zamecnikova A	Kuwait Cancer Control Center, Dep of Hematology, Laboratory of Cancer Genetics, Kuwait	-	-	-	3 yrs	F	Positive for CD10 (90%), CD19 (81%), CD22 (81 %), 13 (61%), 33 (82%), 79a (38%), 34 (82%), HLDR (90%) and TdT (56%)	B-lineage ALL	 48,XX,+16,+18
Atlas Genet Cytogenet Oncol Haematol	100056	tX11q22q23ZamecID100056.txt	Chromosomal translocation t(X;11)(q22;q23) involving the MLL gene	09-2011	Adriana Zamecnikova, Soad Al Bahar, Hassan A Al Jafar, Rames Pandita	Zamecnikova A, Al Bahar S, Al Jafar HA, Pandita R	Kuwait Cancer Control Center, Dep of Hematology, Laboratory of Cancer Genetics, Kuwait (AZ, SAB, RP); Dep of Hematology, Amiri Hospital, Kuwait (HAAJ)	-	-	-	15 mths	M	M4. CD13+,CD14+, CD15+, CD33+, CD45+, CD64+ and MPO.	Acute myelomonocytic leukemia	
Atlas Genet Cytogenet Oncol Haematol	100066	tX20q13q13FigueiredoID100066.txt	Translocation t(X;20)(q13;q13.3) as a secondary chromosome abnormality in a patient with 5q-: a case report	01-2013	Carlos Augusto Figueiredo Correia, Juliana Lino Rodrigues de Matos, Cristina Alonso Ratis, Silvia Helena A Figueira, Renata Kiyomi Kishimoto, Elvira D Rodrigues Pereira Velloso	Figueiredo Correia CA, Rodrigues de Matos JL, Alonso Ratis C, Figueira SHA, Kishimoto RK, Rodrigues Pereira Velloso ED	Laboratorio de Tecnicas Especiais- Citogenetica do Hospital Israelita Albert Einstein, Sao Paulo, Brazil (CAFC, CAR, SHAF, RKK, EDRPV); Hospital das Clinicas da Universidade Federal de Minas Gerais, Minas Gerais, Brazil (CAFC); Hemomed, Sao Paulo, Brazil (JLRdM)	+ Low risk myelodysplastic syndrome (refractory anemia) diagnosed 32 months before (December, 2009).	-	-	76 yrs	F		Myelodysplastic Syndrome - Refractory citopenia with multilineage dysplasia and ringed sideroblasts (WHO classification).	 46,XX,del(5)(q13q31)[1]/46,X,t(X;20)(q13;q13.3),del(5(q13q31))[11]/46,XX[8]