ARMCX2 (arm protein lost in epithelial cancers, X chromosome, 2)

2003-07-01   Jean-Loup Huret , Sylvie Senon 

Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France

Identity

HGNC
LOCATION
Xq22.1
LOCUSID
ALIAS
ALEX2 (arm protein lost in epithelial cancers, X chromosome, 2)
FUSION GENES

DNA/RNA

Description

spans 4.6 kb

Transcription

main transcript: 2.7 kb; other transcripts: 1.4 and 7 kb.

Proteins

Description

632 amino acids; contains a transmembrane domain in N term, and a arm (armadillo) repeat

Expression

wide in normal tissues, except leucocytes; lost or significantly reduced in carcinomas

Homology

with ALEX1 and ALEX3

Implicated in

Bibliography

Pubmed IDLast YearTitleAuthors
111625202001ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.Kurochkin IV et al

Other Information

Locus ID:

NCBI: 9823
MIM: 300363
HGNC: 16869
Ensembl: ENSG00000184867

Variants:

dbSNP: 9823
ClinVar: 9823
TCGA: ENSG00000184867
COSMIC: ARMCX2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184867ENST00000328766Q7L311
ENSG00000184867ENST00000328766A0A024RCG7
ENSG00000184867ENST00000330154Q7L311
ENSG00000184867ENST00000330154A0A024RCG7
ENSG00000184867ENST00000356824Q7L311
ENSG00000184867ENST00000356824A0A024RCG7
ENSG00000184867ENST00000413506Q5H9E1
ENSG00000184867ENST00000431597Q5H9D7
ENSG00000184867ENST00000433318Q5H9E0
ENSG00000184867ENST00000440675A0A0B4J1X4
ENSG00000184867ENST00000458024A0A1B0GXK8

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
222492492012Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling.86

Citation

Jean-Loup Huret ; Sylvie Senon

ARMCX2 (arm protein lost in epithelial cancers, X chromosome, 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-07-01

Online version: http://atlasgeneticsoncology.org/gene/478/armcx2