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ARMCX3 (arm protein lost in epithelial cancers, X chromosome, 3)

Written2003-07Jean-Loup Huret, Sylvie Senon
Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France

(Note : for Links provided by Atlas : click)


Other aliasALEX3 (arm protein lost in epithelial cancers, X chromosome, 3)
LocusID (NCBI) 51566
Atlas_Id 479
Location Xq22.1  [Link to chromosome band Xq22]
Location_base_pair Starts at and ends at bp from pter
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FRAS1 (4q21.21) / ARMCX3 (Xq22.1)NEDD4 (15q21.3) / ARMCX3 (Xq22.1)


Description spans 3.3 kb
Transcription transcript: 2.0 kb


Description 379 amino acids, 42.5 kDa; contains a transmembrane domain in N term, and a arm (armadillo) repeat
Homology with ALEX1 and ALEX2


Note may be involved in tumorigenesis, but further studies are needed


ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.
Kurochkin IV, Yonemitsu N, Funahashi SI, Nomura H
Biochemical and biophysical research communications. 2001 ; 280 (1) : 340-347.
PMID 11162520


This paper should be referenced as such :
Huret, JL ; Senon, S
ALEX3 (arm protein lost in epithelial cancers, X chromosome, 3)
Atlas Genet Cytogenet Oncol Haematol. 2003;7(3):168-168.
Free journal version : [ pdf ]   [ DOI ]
On line version :

External links

Genomic and cartography
Gene and transcription
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)51566
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Protein Interaction databases
Ontologies - Pathways
Clinical trials, drugs, therapy
canSAR (ICR) (select the gene name)
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Oct 18 17:28:04 CEST 2018

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