Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZFHX3 (zinc finger homeobox 3)

Identity

Alias_symbol (synonym)FLJ26184
Other aliasATBF1
ATBT
C16orf47
ZFH-3
ZNF927
HGNC (Hugo) ZFHX3
LocusID (NCBI) 463
Atlas_Id 60963
Location 16q22.2  [Link to chromosome band 16q22]
Location_base_pair Starts at 72782887 and ends at 73048375 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZFHX3   777
Cards
Entrez_Gene (NCBI)ZFHX3  463  zinc finger homeobox 3
AliasesATBF1; ATBT; C16orf47; ZFH-3; 
ZNF927
GeneCards (Weizmann)ZFHX3
Ensembl hg19 (Hinxton)ENSG00000140836 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140836 [Gene_View]  ENSG00000140836 [Sequence]  chr16:72782887-73048375 [Contig_View]  ZFHX3 [Vega]
ICGC DataPortalENSG00000140836
TCGA cBioPortalZFHX3
AceView (NCBI)ZFHX3
Genatlas (Paris)ZFHX3
WikiGenes463
SOURCE (Princeton)ZFHX3
Genetics Home Reference (NIH)ZFHX3
Genomic and cartography
GoldenPath hg38 (UCSC)ZFHX3  -     chr16:72782887-73048375 -  16q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFHX3  -     16q22.2   [Description]    (hg19-Feb_2009)
GoldenPathZFHX3 - 16q22.2 [CytoView hg19]  ZFHX3 - 16q22.2 [CytoView hg38]
ImmunoBaseENSG00000140836
Mapping of homologs : NCBIZFHX3 [Mapview hg19]  ZFHX3 [Mapview hg38]
OMIM104155   176807   
Gene and transcription
Genbank (Entrez)AK129695 BC029653 BC043190 D10250 L32832
RefSeq transcript (Entrez)NM_001164766 NM_006885
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZFHX3
Alternative Splicing GalleryENSG00000140836
Gene ExpressionZFHX3 [ NCBI-GEO ]   ZFHX3 [ EBI - ARRAY_EXPRESS ]   ZFHX3 [ SEEK ]   ZFHX3 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFHX3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)463
GTEX Portal (Tissue expression)ZFHX3
Human Protein AtlasENSG00000140836-ZFHX3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15911   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15911  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15911
Splice isoforms : SwissVarQ15911
PhosPhoSitePlusQ15911
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Homeobox-like_sf    Homeobox_CS    Homeobox_dom    Matrin/U1-like-C_Znf_C2H2    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)Homeodomain (PF00046)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00046    pfam00096   
Domain families : Smart (EMBL)HOX (SM00389)  ZnF_C2H2 (SM00355)  ZnF_U1 (SM00451)  
Conserved Domain (NCBI)ZFHX3
DMDM Disease mutations463
Blocks (Seattle)ZFHX3
PDB (RSDB)2DA1    2DA2    2DA3   
PDB Europe2DA1    2DA2    2DA3   
PDB (PDBSum)2DA1    2DA2    2DA3   
PDB (IMB)2DA1    2DA2    2DA3   
Structural Biology KnowledgeBase2DA1    2DA2    2DA3   
SCOP (Structural Classification of Proteins)2DA1    2DA2    2DA3   
CATH (Classification of proteins structures)2DA1    2DA2    2DA3   
SuperfamilyQ15911
Human Protein Atlas [tissue]ENSG00000140836-ZFHX3 [tissue]
Peptide AtlasQ15911
HPRD16623
IPIIPI00014186   IPI00219003   
Protein Interaction databases
DIP (DOE-UCLA)Q15911
IntAct (EBI)Q15911
FunCoupENSG00000140836
BioGRIDZFHX3
STRING (EMBL)ZFHX3
ZODIACZFHX3
Ontologies - Pathways
QuickGOQ15911
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  nucleus  nucleus  nucleoplasm  transcription factor complex  cytoplasm  regulation of transcription, DNA-templated  transcription by RNA polymerase II  cell cycle arrest  brain development  muscle organ development  zinc ion binding  nuclear body  enzyme binding  circadian regulation of gene expression  transcription regulatory region DNA binding  regulation of neuron differentiation  positive regulation of cell adhesion  positive regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  response to transforming growth factor beta  regulation of locomotor rhythm  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  nucleus  nucleus  nucleoplasm  transcription factor complex  cytoplasm  regulation of transcription, DNA-templated  transcription by RNA polymerase II  cell cycle arrest  brain development  muscle organ development  zinc ion binding  nuclear body  enzyme binding  circadian regulation of gene expression  transcription regulatory region DNA binding  regulation of neuron differentiation  positive regulation of cell adhesion  positive regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  response to transforming growth factor beta  regulation of locomotor rhythm  
NDEx NetworkZFHX3
Atlas of Cancer Signalling NetworkZFHX3
Wikipedia pathwaysZFHX3
Orthology - Evolution
OrthoDB463
GeneTree (enSembl)ENSG00000140836
Phylogenetic Trees/Animal Genes : TreeFamZFHX3
HOGENOMQ15911
Homologs : HomoloGeneZFHX3
Homology/Alignments : Family Browser (UCSC)ZFHX3
Gene fusions - Rearrangements
Fusion : QuiverZFHX3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFHX3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFHX3
dbVarZFHX3
ClinVarZFHX3
1000_GenomesZFHX3 
Exome Variant ServerZFHX3
ExAC (Exome Aggregation Consortium)ENSG00000140836
GNOMAD BrowserENSG00000140836
Varsome BrowserZFHX3
Genetic variants : HAPMAP463
Genomic Variants (DGV)ZFHX3 [DGVbeta]
DECIPHERZFHX3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFHX3 
Mutations
ICGC Data PortalZFHX3 
TCGA Data PortalZFHX3 
Broad Tumor PortalZFHX3
OASIS PortalZFHX3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDZFHX3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFHX3
DgiDB (Drug Gene Interaction Database)ZFHX3
DoCM (Curated mutations)ZFHX3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFHX3 (select a term)
intoGenZFHX3
Cancer3DZFHX3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104155    176807   
Orphanet
DisGeNETZFHX3
MedgenZFHX3
Genetic Testing Registry ZFHX3
NextProtQ15911 [Medical]
TSGene463
GENETestsZFHX3
Target ValidationZFHX3
Huge Navigator ZFHX3 [HugePedia]
snp3D : Map Gene to Disease463
BioCentury BCIQZFHX3
ClinGenZFHX3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD463
Chemical/Pharm GKB GenePA162409676
Clinical trialZFHX3
Miscellaneous
canSAR (ICR)ZFHX3 (select the gene name)
DataMed IndexZFHX3
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFHX3
EVEXZFHX3
GoPubMedZFHX3
iHOPZFHX3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Feb 19 17:21:07 CET 2020

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