A1BG (alpha-1-B glycoprotein)

2008-12-01  

Identity

HGNC
LOCATION
19q13.43
LOCUSID
ALIAS
A1B,ABG,GAB,HYST2477
FUSION GENES

Other Information

Locus ID:

NCBI: 1
MIM: 138670
HGNC: 5
Ensembl: ENSG00000121410

Variants:

dbSNP: 1
ClinVar: 1
TCGA: ENSG00000121410
COSMIC: A1BG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121410ENST00000263100P04217
ENSG00000121410ENST00000263100V9HWD8
ENSG00000121410ENST00000600966M0R009

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
187060982008Proteomic analysis identifies MMP-9, DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients.70
232847582012Integrative proteomics and tissue microarray profiling indicate the association between overexpressed serum proteins and non-small cell lung cancer.27
234185442013Identification of novel autoantigen in the synovial fluid of rheumatoid arthritis patients using an immunoproteomics approach.22
154614602004Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma.21
236903422013Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes.12
215912662011Discovery and initial validation of α 1-B glycoprotein fragmentation as a differential urinary biomarker in pediatric steroid-resistant nephrotic syndrome.9
201164142010Human CRISP-3 binds serum alpha(1)B-glycoprotein across species.4

Citation

Dessen P

A1BG (alpha-1-B glycoprotein)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50521/a1bg