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AADAT (aminoadipate aminotransferase)

Identity

Alias_symbol (synonym)KATII
KAT2
KYAT2
Other alias
HGNC (Hugo) AADAT
LocusID (NCBI) 51166
Atlas_Id 60013
Location 4q33  [Link to chromosome band 4q33]
Location_base_pair Starts at 170060222 and ends at 170090221 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MFAP3L (4q33) / AADAT (4q33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AADAT   17929
Cards
Entrez_Gene (NCBI)AADAT  51166  aminoadipate aminotransferase
AliasesKAT2; KATII; KYAT2
GeneCards (Weizmann)AADAT
Ensembl hg19 (Hinxton)ENSG00000109576 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109576 [Gene_View]  chr4:170060222-170090221 [Contig_View]  AADAT [Vega]
ICGC DataPortalENSG00000109576
TCGA cBioPortalAADAT
AceView (NCBI)AADAT
Genatlas (Paris)AADAT
WikiGenes51166
SOURCE (Princeton)AADAT
Genetics Home Reference (NIH)AADAT
Genomic and cartography
GoldenPath hg38 (UCSC)AADAT  -     chr4:170060222-170090221 -  4q33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AADAT  -     4q33   [Description]    (hg19-Feb_2009)
EnsemblAADAT - 4q33 [CytoView hg19]  AADAT - 4q33 [CytoView hg38]
Mapping of homologs : NCBIAADAT [Mapview hg19]  AADAT [Mapview hg38]
OMIM611754   
Gene and transcription
Genbank (Entrez)AF481738 AI190763 AK055952 AK314729 BC031068
RefSeq transcript (Entrez)NM_001286682 NM_001286683 NM_016228 NM_182662
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AADAT
Cluster EST : UnigeneHs.529735 [ NCBI ]
CGAP (NCI)Hs.529735
Alternative Splicing GalleryENSG00000109576
Gene ExpressionAADAT [ NCBI-GEO ]   AADAT [ EBI - ARRAY_EXPRESS ]   AADAT [ SEEK ]   AADAT [ MEM ]
Gene Expression Viewer (FireBrowse)AADAT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51166
GTEX Portal (Tissue expression)AADAT
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5Z0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5Z0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5Z0
Splice isoforms : SwissVarQ8N5Z0
Catalytic activity : Enzyme2.6.1.39 [ Enzyme-Expasy ]   2.6.1.392.6.1.39 [ IntEnz-EBI ]   2.6.1.39 [ BRENDA ]   2.6.1.39 [ KEGG ]   
PhosPhoSitePlusQ8N5Z0
Domains : Interpro (EBI)Aminotransferase_I/II    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_major_sub1    PyrdxlP-dep_Trfase_major_sub2   
Domain families : Pfam (Sanger)Aminotran_1_2 (PF00155)   
Domain families : Pfam (NCBI)pfam00155   
Conserved Domain (NCBI)AADAT
DMDM Disease mutations51166
Blocks (Seattle)AADAT
PDB (SRS)2QLR    2R2N    2VGZ    2XH1    3DC1    3UE8    4GDY    4GE4    4GE7    4GE9    4GEB    5EFS    5EUN    5TF5   
PDB (PDBSum)2QLR    2R2N    2VGZ    2XH1    3DC1    3UE8    4GDY    4GE4    4GE7    4GE9    4GEB    5EFS    5EUN    5TF5   
PDB (IMB)2QLR    2R2N    2VGZ    2XH1    3DC1    3UE8    4GDY    4GE4    4GE7    4GE9    4GEB    5EFS    5EUN    5TF5   
PDB (RSDB)2QLR    2R2N    2VGZ    2XH1    3DC1    3UE8    4GDY    4GE4    4GE7    4GE9    4GEB    5EFS    5EUN    5TF5   
Structural Biology KnowledgeBase2QLR    2R2N    2VGZ    2XH1    3DC1    3UE8    4GDY    4GE4    4GE7    4GE9    4GEB    5EFS    5EUN    5TF5   
SCOP (Structural Classification of Proteins)2QLR    2R2N    2VGZ    2XH1    3DC1    3UE8    4GDY    4GE4    4GE7    4GE9    4GEB    5EFS    5EUN    5TF5   
CATH (Classification of proteins structures)2QLR    2R2N    2VGZ    2XH1    3DC1    3UE8    4GDY    4GE4    4GE7    4GE9    4GEB    5EFS    5EUN    5TF5   
SuperfamilyQ8N5Z0
Human Protein AtlasENSG00000109576
Peptide AtlasQ8N5Z0
HPRD12392
IPIIPI00395929   IPI00410702   IPI00967398   IPI00967256   IPI00964773   
Protein Interaction databases
DIP (DOE-UCLA)Q8N5Z0
IntAct (EBI)Q8N5Z0
FunCoupENSG00000109576
BioGRIDAADAT
STRING (EMBL)AADAT
ZODIACAADAT
Ontologies - Pathways
QuickGOQ8N5Z0
Ontology : AmiGOmitochondrial matrix  2-oxoglutarate metabolic process  glutamate metabolic process  lysine catabolic process  tryptophan catabolic process  biosynthetic process  kynurenine-oxoglutarate transaminase activity  kynurenine-oxoglutarate transaminase activity  tryptophan catabolic process to kynurenine  pyridoxal phosphate binding  L-lysine catabolic process to acetyl-CoA via saccharopine  protein homodimerization activity  2-aminoadipate transaminase activity  2-aminoadipate transaminase activity  kynurenine metabolic process  L-kynurenine metabolic process  
Ontology : EGO-EBImitochondrial matrix  2-oxoglutarate metabolic process  glutamate metabolic process  lysine catabolic process  tryptophan catabolic process  biosynthetic process  kynurenine-oxoglutarate transaminase activity  kynurenine-oxoglutarate transaminase activity  tryptophan catabolic process to kynurenine  pyridoxal phosphate binding  L-lysine catabolic process to acetyl-CoA via saccharopine  protein homodimerization activity  2-aminoadipate transaminase activity  2-aminoadipate transaminase activity  kynurenine metabolic process  L-kynurenine metabolic process  
Pathways : KEGGLysine biosynthesis    Lysine degradation    Tryptophan metabolism   
NDEx NetworkAADAT
Atlas of Cancer Signalling NetworkAADAT
Wikipedia pathwaysAADAT
Orthology - Evolution
OrthoDB51166
GeneTree (enSembl)ENSG00000109576
Phylogenetic Trees/Animal Genes : TreeFamAADAT
HOVERGENQ8N5Z0
HOGENOMQ8N5Z0
Homologs : HomoloGeneAADAT
Homology/Alignments : Family Browser (UCSC)AADAT
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAADAT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AADAT
dbVarAADAT
ClinVarAADAT
1000_GenomesAADAT 
Exome Variant ServerAADAT
ExAC (Exome Aggregation Consortium)AADAT (select the gene name)
Genetic variants : HAPMAP51166
Genomic Variants (DGV)AADAT [DGVbeta]
DECIPHERAADAT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAADAT 
Mutations
ICGC Data PortalAADAT 
TCGA Data PortalAADAT 
Broad Tumor PortalAADAT
OASIS PortalAADAT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAADAT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAADAT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AADAT
DgiDB (Drug Gene Interaction Database)AADAT
DoCM (Curated mutations)AADAT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AADAT (select a term)
intoGenAADAT
Cancer3DAADAT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611754   
Orphanet
MedgenAADAT
Genetic Testing Registry AADAT
NextProtQ8N5Z0 [Medical]
TSGene51166
GENETestsAADAT
Target ValidationAADAT
Huge Navigator AADAT [HugePedia]
snp3D : Map Gene to Disease51166
BioCentury BCIQAADAT
ClinGenAADAT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51166
Chemical/Pharm GKB GenePA24364
Clinical trialAADAT
Miscellaneous
canSAR (ICR)AADAT (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAADAT
EVEXAADAT
GoPubMedAADAT
iHOPAADAT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:36:57 CEST 2017

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