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ABCB10 (ATP binding cassette subfamily B member 10)

Identity

Alias_namesATP-binding cassette
Alias_symbol (synonym)EST20237
M-ABC2
MTABC2
Other alias
HGNC (Hugo) ABCB10
LocusID (NCBI) 23456
Atlas_Id 50967
Location 1q42.13  [Link to chromosome band 1q42]
Location_base_pair Starts at 229516582 and ends at 229558695 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ABCB10   41
Cards
Entrez_Gene (NCBI)ABCB10  23456  ATP binding cassette subfamily B member 10
AliasesEST20237; M-ABC2; MTABC2
GeneCards (Weizmann)ABCB10
Ensembl hg19 (Hinxton)ENSG00000135776 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135776 [Gene_View]  ENSG00000135776 [Sequence]  chr1:229516582-229558695 [Contig_View]  ABCB10 [Vega]
ICGC DataPortalENSG00000135776
TCGA cBioPortalABCB10
AceView (NCBI)ABCB10
Genatlas (Paris)ABCB10
WikiGenes23456
SOURCE (Princeton)ABCB10
Genetics Home Reference (NIH)ABCB10
Genomic and cartography
GoldenPath hg38 (UCSC)ABCB10  -     chr1:229516582-229558695 -  1q42.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ABCB10  -     1q42.13   [Description]    (hg19-Feb_2009)
EnsemblABCB10 - 1q42.13 [CytoView hg19]  ABCB10 - 1q42.13 [CytoView hg38]
Mapping of homologs : NCBIABCB10 [Mapview hg19]  ABCB10 [Mapview hg38]
OMIM605454   
Gene and transcription
Genbank (Entrez)AB013380 AF216833 AF277184 AK172794 BC064930
RefSeq transcript (Entrez)NM_012089
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ABCB10
Cluster EST : UnigeneHs.17614 [ NCBI ]
CGAP (NCI)Hs.17614
Alternative Splicing GalleryENSG00000135776
Gene ExpressionABCB10 [ NCBI-GEO ]   ABCB10 [ EBI - ARRAY_EXPRESS ]   ABCB10 [ SEEK ]   ABCB10 [ MEM ]
Gene Expression Viewer (FireBrowse)ABCB10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23456
GTEX Portal (Tissue expression)ABCB10
Human Protein AtlasENSG00000135776-ABCB10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRK6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRK6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRK6
Splice isoforms : SwissVarQ9NRK6
PhosPhoSitePlusQ9NRK6
Domaine pattern : Prosite (Expaxy)ABC_TM1F (PS50929)    ABC_TRANSPORTER_1 (PS00211)    ABC_TRANSPORTER_2 (PS50893)   
Domains : Interpro (EBI)AAA+_ATPase    ABC1_TM_dom    ABC1_TM_sf    ABC_transporter-like    ABC_transporter_CS    ABCB10-like    P-loop_NTPase   
Domain families : Pfam (Sanger)ABC_membrane (PF00664)    ABC_tran (PF00005)   
Domain families : Pfam (NCBI)pfam00664    pfam00005   
Domain families : Smart (EMBL)AAA (SM00382)  
Conserved Domain (NCBI)ABCB10
DMDM Disease mutations23456
Blocks (Seattle)ABCB10
PDB (SRS)3ZDQ    4AYT    4AYW    4AYX   
PDB (PDBSum)3ZDQ    4AYT    4AYW    4AYX   
PDB (IMB)3ZDQ    4AYT    4AYW    4AYX   
PDB (RSDB)3ZDQ    4AYT    4AYW    4AYX   
Structural Biology KnowledgeBase3ZDQ    4AYT    4AYW    4AYX   
SCOP (Structural Classification of Proteins)3ZDQ    4AYT    4AYW    4AYX   
CATH (Classification of proteins structures)3ZDQ    4AYT    4AYW    4AYX   
SuperfamilyQ9NRK6
Human Protein Atlas [tissue]ENSG00000135776-ABCB10 [tissue]
Peptide AtlasQ9NRK6
HPRD09263
IPIIPI00015826   IPI00387014   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRK6
IntAct (EBI)Q9NRK6
FunCoupENSG00000135776
BioGRIDABCB10
STRING (EMBL)ABCB10
ZODIACABCB10
Ontologies - Pathways
QuickGOQ9NRK6
Ontology : AmiGOtransporter activity  ATP binding  mitochondrial inner membrane  mitochondrial transport  integral component of membrane  integral component of mitochondrial membrane  ATPase activity, coupled to transmembrane movement of substances  ATPase activity, coupled to transmembrane movement of substances  protein homodimerization activity  transmembrane transport  transmembrane transport  
Ontology : EGO-EBItransporter activity  ATP binding  mitochondrial inner membrane  mitochondrial transport  integral component of membrane  integral component of mitochondrial membrane  ATPase activity, coupled to transmembrane movement of substances  ATPase activity, coupled to transmembrane movement of substances  protein homodimerization activity  transmembrane transport  transmembrane transport  
Pathways : KEGGABC transporters   
NDEx NetworkABCB10
Atlas of Cancer Signalling NetworkABCB10
Wikipedia pathwaysABCB10
Orthology - Evolution
OrthoDB23456
GeneTree (enSembl)ENSG00000135776
Phylogenetic Trees/Animal Genes : TreeFamABCB10
HOVERGENQ9NRK6
HOGENOMQ9NRK6
Homologs : HomoloGeneABCB10
Homology/Alignments : Family Browser (UCSC)ABCB10
Gene fusions - Rearrangements
Fusion : QuiverABCB10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerABCB10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ABCB10
dbVarABCB10
ClinVarABCB10
1000_GenomesABCB10 
Exome Variant ServerABCB10
ExAC (Exome Aggregation Consortium)ENSG00000135776
GNOMAD BrowserENSG00000135776
Varsome BrowserABCB10
Genetic variants : HAPMAP23456
Genomic Variants (DGV)ABCB10 [DGVbeta]
DECIPHERABCB10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisABCB10 
Mutations
ICGC Data PortalABCB10 
TCGA Data PortalABCB10 
Broad Tumor PortalABCB10
OASIS PortalABCB10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICABCB10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDABCB10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ABCB10
DgiDB (Drug Gene Interaction Database)ABCB10
DoCM (Curated mutations)ABCB10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ABCB10 (select a term)
intoGenABCB10
Cancer3DABCB10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605454   
Orphanet
DisGeNETABCB10
MedgenABCB10
Genetic Testing Registry ABCB10
NextProtQ9NRK6 [Medical]
TSGene23456
GENETestsABCB10
Target ValidationABCB10
Huge Navigator ABCB10 [HugePedia]
snp3D : Map Gene to Disease23456
BioCentury BCIQABCB10
ClinGenABCB10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23456
Chemical/Pharm GKB GenePA24385
Clinical trialABCB10
Miscellaneous
canSAR (ICR)ABCB10 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineABCB10
EVEXABCB10
GoPubMedABCB10
iHOPABCB10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:07:08 CEST 2018

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