ABCB9 (ATP binding cassette subfamily B member 9)

2008-03-01  

Identity

HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
EST122234,TAPL
FUSION GENES

Other Information

Locus ID:

NCBI: 23457
MIM: 605453
HGNC: 50
Ensembl: ENSG00000150967

Variants:

dbSNP: 23457
ClinVar: 23457
TCGA: ENSG00000150967
COSMIC: ABCB9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000150967ENST00000280560Q9NP78
ENSG00000150967ENST00000280560A0A024RBU1
ENSG00000150967ENST00000344275Q9NP78
ENSG00000150967ENST00000346530Q9NP78
ENSG00000150967ENST00000392439Q9NP78
ENSG00000150967ENST00000392439A0A024RBU1
ENSG00000150967ENST00000426173H7C478
ENSG00000150967ENST00000442028Q6P2Q0
ENSG00000150967ENST00000442833Q9NP78
ENSG00000150967ENST00000536976F5H5F9
ENSG00000150967ENST00000537276F5H0G0
ENSG00000150967ENST00000540285Q9NP78
ENSG00000150967ENST00000540971F5GX86
ENSG00000150967ENST00000541424F5GXZ5
ENSG00000150967ENST00000542448F5GYI2
ENSG00000150967ENST00000542678Q9NP78
ENSG00000150967ENST00000542678A0A024RBU1
ENSG00000150967ENST00000543935F5H5I5
ENSG00000150967ENST00000545373F5H4Y2
ENSG00000150967ENST00000546077F5H5Q0
ENSG00000150967ENST00000546289F5H7U2

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
ABC transportersKEGGko02010
ABC transportersKEGGhsa02010
LysosomeKEGGko04142
LysosomeKEGGhsa04142
Transmembrane transport of small moleculesREACTOMER-HSA-382551
ABC-family proteins mediated transportREACTOMER-HSA-382556

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
179778212007Identification of a lysosomal peptide transport system induced during dendritic cell development.13
158634922005Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9).12
226416972012The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2.12
203778232010Tuning the cellular trafficking of the lysosomal peptide transporter TAPL by its N-terminal domain.10
184343092008Peptide specificity and lipid activation of the lysosomal transport complex ABCB9 (TAPL).8
189520562008Functional dissection of transmembrane domains of human TAP-like (ABCB9).6
165540242006Examination of drug resistance activity of human TAP-like (ABCB9) expressed in yeast.4
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.3
240139302013Conformational stabilization of the membrane embedded targeting domain of the lysosomal peptide transporter TAPL for solution NMR.3
303531402018Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL.2

Citation

Dessen P

ABCB9 (ATP binding cassette subfamily B member 9)

Atlas Genet Cytogenet Oncol Haematol. 2008-03-01

Online version: http://atlasgeneticsoncology.org/gene/50059/abcb9