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ABCC2 (ATP-binding cassette, sub-family C (CFTR/MRP), member 2)

Identity

Other namesABC30
CMOAT
DJS
MRP2
cMRP
HGNC (Hugo) ABCC2
LocusID (NCBI) 1244
Location 10q24.2
Location_base_pair Starts at 101542355 and ends at 101611949 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ABCC2   53
Cards
Entrez_Gene (NCBI)ABCC2  1244  ATP-binding cassette, sub-family C (CFTR/MRP), member 2
GeneCards (Weizmann)ABCC2
Ensembl (Hinxton)ENSG00000023839 [Gene_View]  chr10:101542355-101611949 [Contig_View]  ABCC2 [Vega]
ICGC DataPortalENSG00000023839
AceView (NCBI)ABCC2
Genatlas (Paris)ABCC2
WikiGenes1244
SOURCE (Princeton)NM_000392
Genomic and cartography
GoldenPath (UCSC)ABCC2  -  10q24.2   chr10:101542355-101611949 +  10q24.2   [Description]    (hg19-Feb_2009)
EnsemblABCC2 - 10q24.2 [CytoView]
Mapping of homologs : NCBIABCC2 [Mapview]
OMIM237500   601107   
Gene and transcription
Genbank (Entrez)BC136419 BM765259 CB120555 U49248 U63970
RefSeq transcript (Entrez)NM_000392
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NG_011798 NT_030059 NW_001838006 NW_004929376
Consensus coding sequences : CCDS (NCBI)ABCC2
Cluster EST : UnigeneHs.368243 [ NCBI ]
CGAP (NCI)Hs.368243
Alternative Splicing : Fast-db (Paris)GSHG0003615
Alternative Splicing GalleryENSG00000023839
Gene ExpressionABCC2 [ NCBI-GEO ]     ABCC2 [ SEEK ]   ABCC2 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92887 (Uniprot)
NextProtQ92887  [Medical]
With graphics : InterProQ92887
Splice isoforms : SwissVarQ92887 (Swissvar)
Domaine pattern : Prosite (Expaxy)ABC_TM1F (PS50929)    ABC_TRANSPORTER_1 (PS00211)    ABC_TRANSPORTER_2 (PS50893)   
Domains : Interpro (EBI)AAA+_ATPase    ABC1_TM_dom    ABC_transporter-like    ABC_transporter_CS    ABC_transptr_TM_dom    Multidrug-R_assoc    P-loop_NTPase   
Related proteins : CluSTrQ92887
Domain families : Pfam (Sanger)ABC_membrane (PF00664)    ABC_tran (PF00005)   
Domain families : Pfam (NCBI)pfam00664    pfam00005   
Domain families : Smart (EMBL)AAA (SM00382)  
DMDM Disease mutations1244
Blocks (Seattle)Q92887
Human Protein AtlasENSG00000023839
Peptide AtlasQ92887
HPRD03065
IPIIPI00023868   IPI00815960   IPI00646446   
Protein Interaction databases
DIP (DOE-UCLA)Q92887
IntAct (EBI)Q92887
FunCoupENSG00000023839
BioGRIDABCC2
InParanoidQ92887
Interologous Interaction database Q92887
IntegromeDBABCC2
STRING (EMBL)ABCC2
Ontologies - Pathways
Ontology : AmiGOprotein binding  ATP binding  plasma membrane  integral component of plasma membrane  ATP catabolic process  transport  drug transmembrane transport  response to oxidative stress  organic anion transmembrane transporter activity  response to heat  prostaglandin transport  apical plasma membrane  protein domain specific binding  cellular chloride ion homeostasis  response to methotrexate  ATPase activity, coupled to transmembrane movement of substances  response to estrogen  intercellular canaliculus  response to arsenic-containing substance  transmembrane transport  thyroid hormone transport  
Ontology : EGO-EBIprotein binding  ATP binding  plasma membrane  integral component of plasma membrane  ATP catabolic process  transport  drug transmembrane transport  response to oxidative stress  organic anion transmembrane transporter activity  response to heat  prostaglandin transport  apical plasma membrane  protein domain specific binding  cellular chloride ion homeostasis  response to methotrexate  ATPase activity, coupled to transmembrane movement of substances  response to estrogen  intercellular canaliculus  response to arsenic-containing substance  transmembrane transport  thyroid hormone transport  
Pathways : BIOCARTANuclear Receptors in Lipid Metabolism and Toxicity [Genes]   
Pathways : KEGGABC transporters    Bile secretion   
Protein Interaction DatabaseABCC2
Wikipedia pathwaysABCC2
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ABCC2
SNP (GeneSNP Utah)ABCC2
SNP : HGBaseABCC2
Genetic variants : HAPMAPABCC2
1000_GenomesABCC2 
ICGC programENSG00000023839 
CONAN: Copy Number AnalysisABCC2 
Somatic Mutations in Cancer : COSMICABCC2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Pharmacogenomics of Infectious Diseases (PGx_IfD )
Mutations and Diseases : HGMDABCC2
OMIM237500    601107   
MedgenABCC2
GENETestsABCC2
Disease Genetic AssociationABCC2
Huge Navigator ABCC2 [HugePedia]  ABCC2 [HugeCancerGEM]
Genomic VariantsABCC2  ABCC2 [DGVbeta]
Exome VariantABCC2
dbVarABCC2
ClinVarABCC2
snp3D : Map Gene to Disease1244
General knowledge
Homologs : HomoloGeneABCC2
Homology/Alignments : Family Browser (UCSC)ABCC2
Phylogenetic Trees/Animal Genes : TreeFamABCC2
Chemical/Protein Interactions : CTD1244
Chemical/Pharm GKB GenePA116
Clinical trialABCC2
Cancer Resource (Charite)ENSG00000023839
Other databases
Probes
Litterature
PubMed246 Pubmed reference(s) in Entrez
CoreMineABCC2
iHOPABCC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 12:29:50 CEST 2014

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