Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ABCC6 (ATP binding cassette subfamily C member 6)

Identity

Other namesABC34
ARA
EST349056
GACI2
MLP1
MOAT-E
MOATE
MRP6
PXE
PXE1
URG7
HGNC (Hugo) ABCC6
LocusID (NCBI) 368
Atlas_Id 543
Location 16p13.11
Location_base_pair Starts at 16315044 and ends at 16317328 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ABCC6 (16p13.11) / C16orf70 (16q22.1)ABCC6 (16p13.11) / SEMA4G (10q24.31)ABCC6 16p13.11 / C16orf70 16q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ABCC6   57
Cards
Entrez_Gene (NCBI)ABCC6  368  ATP binding cassette subfamily C member 6
GeneCards (Weizmann)ABCC6
Ensembl hg19 (Hinxton)ENSG00000091262 [Gene_View]  chr16:16315044-16317328 [Contig_View]  ABCC6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000091262 [Gene_View]  chr16:16315044-16317328 [Contig_View]  ABCC6 [Vega]
ICGC DataPortalENSG00000091262
TCGA cBioPortalABCC6
AceView (NCBI)ABCC6
Genatlas (Paris)ABCC6
WikiGenes368
SOURCE (Princeton)ABCC6
Genomic and cartography
GoldenPath hg19 (UCSC)ABCC6  -     chr16:16315044-16317328 -  16p13.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ABCC6  -     16p13.11   [Description]    (hg38-Dec_2013)
EnsemblABCC6 - 16p13.11 [CytoView hg19]  ABCC6 - 16p13.11 [CytoView hg38]
Mapping of homologs : NCBIABCC6 [Mapview hg19]  ABCC6 [Mapview hg38]
OMIM177850   264800   603234   614473   
Gene and transcription
Genbank (Entrez)AF076622 AF168791 AI074459 AK298295 AM711638
RefSeq transcript (Entrez)NM_001079528 NM_001171
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_007558 NT_010393 NT_187607 NW_004929400
Consensus coding sequences : CCDS (NCBI)ABCC6
Cluster EST : UnigeneHs.442182 [ NCBI ]
CGAP (NCI)Hs.442182
Alternative Splicing : Fast-db (Paris)GSHG0011662
Alternative Splicing GalleryENSG00000091262
Gene ExpressionABCC6 [ NCBI-GEO ]   ABCC6 [ EBI - ARRAY_EXPRESS ]   ABCC6 [ SEEK ]   ABCC6 [ MEM ]
Gene Expression Viewer (FireBrowse)ABCC6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)368
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95255 (Uniprot)
NextProtO95255  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95255
Splice isoforms : SwissVarO95255 (Swissvar)
PhosPhoSitePlusO95255
Domaine pattern : Prosite (Expaxy)ABC_TM1F (PS50929)    ABC_TRANSPORTER_1 (PS00211)    ABC_TRANSPORTER_2 (PS50893)   
Domains : Interpro (EBI)AAA+_ATPase    ABC1_TM_dom    ABC_transporter-like    ABC_transporter_CS    ABCC6    Multidrug-R_assoc    P-loop_NTPase   
Domain families : Pfam (Sanger)ABC_membrane (PF00664)    ABC_tran (PF00005)   
Domain families : Pfam (NCBI)pfam00664    pfam00005   
Domain families : Smart (EMBL)AAA (SM00382)  
DMDM Disease mutations368
Blocks (Seattle)ABCC6
SuperfamilyO95255
Human Protein AtlasENSG00000091262
Peptide AtlasO95255
HPRD04453
IPIIPI00029455   IPI00748343   IPI00015182   IPI01012908   IPI01012725   IPI00643499   
Protein Interaction databases
DIP (DOE-UCLA)O95255
IntAct (EBI)O95255
FunCoupENSG00000091262
BioGRIDABCC6
STRING (EMBL)ABCC6
ZODIACABCC6
Ontologies - Pathways
QuickGOO95255
Ontology : AmiGOtransporter activity  ATP binding  nucleus  endoplasmic reticulum membrane  plasma membrane  plasma membrane  transport  visual perception  metabolic process  integral component of membrane  basolateral plasma membrane  apical plasma membrane  lateral plasma membrane  response to drug  ATPase activity, coupled to transmembrane movement of substances  anion transmembrane-transporting ATPase activity  transmembrane transport  anion transmembrane transport  
Ontology : EGO-EBItransporter activity  ATP binding  nucleus  endoplasmic reticulum membrane  plasma membrane  plasma membrane  transport  visual perception  metabolic process  integral component of membrane  basolateral plasma membrane  apical plasma membrane  lateral plasma membrane  response to drug  ATPase activity, coupled to transmembrane movement of substances  anion transmembrane-transporting ATPase activity  transmembrane transport  anion transmembrane transport  
Pathways : KEGGABC transporters   
NDEx Network
Atlas of Cancer Signalling NetworkABCC6
Wikipedia pathwaysABCC6
Orthology - Evolution
OrthoDB368
GeneTree (enSembl)ENSG00000091262
Phylogenetic Trees/Animal Genes : TreeFamABCC6
Homologs : HomoloGeneABCC6
Homology/Alignments : Family Browser (UCSC)ABCC6
Gene fusions - Rearrangements
Fusion: TCGAABCC6 16p13.11 C16orf70 16q22.1 LAML
Polymorphisms : SNP, variants
NCBI Variation ViewerABCC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ABCC6
dbVarABCC6
ClinVarABCC6
1000_GenomesABCC6 
Exome Variant ServerABCC6
ExAC (Exome Aggregation Consortium)ABCC6 (select the gene name)
SNP (GeneSNP Utah)ABCC6
SNP : HGBaseABCC6
Genetic variants : HAPMAPABCC6
Genomic Variants (DGV)ABCC6 [DGVbeta]
Mutations
ICGC Data PortalABCC6 
TCGA Data PortalABCC6 
Broad Tumor PortalABCC6
OASIS PortalABCC6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICABCC6 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
LOVD (Leiden Open Variation Database)LOVD at NCBI
BioMutasearch ABCC6
DgiDB (Drug Gene Interaction Database)ABCC6
DoCM (Curated mutations)ABCC6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ABCC6 (select a term)
intoGenABCC6
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:16315044-16317328
CONAN: Copy Number AnalysisABCC6 
Mutations and Diseases : HGMDABCC6
OMIM177850    264800    603234    614473   
MedgenABCC6
Genetic Testing Registry ABCC6
NextProtO95255 [Medical]
TSGene368
GENETestsABCC6
Huge Navigator ABCC6 [HugePedia]  ABCC6 [HugeCancerGEM]
snp3D : Map Gene to Disease368
BioCentury BCIQABCC6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD368
Chemical/Pharm GKB GenePA58
Clinical trialABCC6
Miscellaneous
canSAR (ICR)ABCC6 (select the gene name)
Probes
Litterature
PubMed106 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineABCC6
GoPubMedABCC6
iHOPABCC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Apr 16 17:34:23 CEST 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.