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ABCG4 (ATP binding cassette subfamily G member 4)

Identity

Alias_namesATP-binding cassette
Alias_symbol (synonym)WHITE2
Other alias
HGNC (Hugo) ABCG4
LocusID (NCBI) 64137
Atlas_Id 55783
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 119149589 and ends at 119162665 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ABCG4   13884
Cards
Entrez_Gene (NCBI)ABCG4  64137  ATP binding cassette subfamily G member 4
AliasesWHITE2
GeneCards (Weizmann)ABCG4
Ensembl hg19 (Hinxton)ENSG00000172350 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172350 [Gene_View]  chr11:119149589-119162665 [Contig_View]  ABCG4 [Vega]
ICGC DataPortalENSG00000172350
TCGA cBioPortalABCG4
AceView (NCBI)ABCG4
Genatlas (Paris)ABCG4
WikiGenes64137
SOURCE (Princeton)ABCG4
Genetics Home Reference (NIH)ABCG4
Genomic and cartography
GoldenPath hg38 (UCSC)ABCG4  -     chr11:119149589-119162665 +  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ABCG4  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblABCG4 - 11q23.3 [CytoView hg19]  ABCG4 - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBIABCG4 [Mapview hg19]  ABCG4 [Mapview hg38]
OMIM607784   
Gene and transcription
Genbank (Entrez)AJ300465 AJ308237 AJ308238 AJ308239 AJ308240
RefSeq transcript (Entrez)NM_001142505 NM_001348191 NM_001348192 NM_022169
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ABCG4
Cluster EST : UnigeneHs.126378 [ NCBI ]
CGAP (NCI)Hs.126378
Alternative Splicing GalleryENSG00000172350
Gene ExpressionABCG4 [ NCBI-GEO ]   ABCG4 [ EBI - ARRAY_EXPRESS ]   ABCG4 [ SEEK ]   ABCG4 [ MEM ]
Gene Expression Viewer (FireBrowse)ABCG4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64137
GTEX Portal (Tissue expression)ABCG4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H172   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H172  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H172
Splice isoforms : SwissVarQ9H172
PhosPhoSitePlusQ9H172
Domaine pattern : Prosite (Expaxy)ABC_TRANSPORTER_1 (PS00211)    ABC_TRANSPORTER_2 (PS50893)   
Domains : Interpro (EBI)AAA+_ATPase    ABC_2_trans    ABC_transporter-like    ABC_transporter_CS    P-loop_NTPase   
Domain families : Pfam (Sanger)ABC2_membrane (PF01061)    ABC_tran (PF00005)   
Domain families : Pfam (NCBI)pfam01061    pfam00005   
Domain families : Smart (EMBL)AAA (SM00382)  
Conserved Domain (NCBI)ABCG4
DMDM Disease mutations64137
Blocks (Seattle)ABCG4
SuperfamilyQ9H172
Human Protein AtlasENSG00000172350
Peptide AtlasQ9H172
HPRD12130
IPIIPI00005579   IPI00815966   IPI00816472   IPI00977168   IPI00978528   
Protein Interaction databases
DIP (DOE-UCLA)Q9H172
IntAct (EBI)Q9H172
FunCoupENSG00000172350
BioGRIDABCG4
STRING (EMBL)ABCG4
ZODIACABCG4
Ontologies - Pathways
QuickGOQ9H172
Ontology : AmiGOprotein binding  ATP binding  plasma membrane  plasma membrane  integral component of membrane  cholesterol transporter activity  cholesterol transporter activity  cholesterol efflux  sterol-transporting ATPase activity  protein homodimerization activity  protein heterodimerization activity  transmembrane transport  
Ontology : EGO-EBIprotein binding  ATP binding  plasma membrane  plasma membrane  integral component of membrane  cholesterol transporter activity  cholesterol transporter activity  cholesterol efflux  sterol-transporting ATPase activity  protein homodimerization activity  protein heterodimerization activity  transmembrane transport  
Pathways : KEGGABC transporters   
NDEx NetworkABCG4
Atlas of Cancer Signalling NetworkABCG4
Wikipedia pathwaysABCG4
Orthology - Evolution
OrthoDB64137
GeneTree (enSembl)ENSG00000172350
Phylogenetic Trees/Animal Genes : TreeFamABCG4
HOVERGENQ9H172
HOGENOMQ9H172
Homologs : HomoloGeneABCG4
Homology/Alignments : Family Browser (UCSC)ABCG4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerABCG4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ABCG4
dbVarABCG4
ClinVarABCG4
1000_GenomesABCG4 
Exome Variant ServerABCG4
ExAC (Exome Aggregation Consortium)ABCG4 (select the gene name)
Genetic variants : HAPMAP64137
Genomic Variants (DGV)ABCG4 [DGVbeta]
DECIPHERABCG4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisABCG4 
Mutations
ICGC Data PortalABCG4 
TCGA Data PortalABCG4 
Broad Tumor PortalABCG4
OASIS PortalABCG4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICABCG4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDABCG4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ABCG4
DgiDB (Drug Gene Interaction Database)ABCG4
DoCM (Curated mutations)ABCG4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ABCG4 (select a term)
intoGenABCG4
Cancer3DABCG4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607784   
Orphanet
MedgenABCG4
Genetic Testing Registry ABCG4
NextProtQ9H172 [Medical]
TSGene64137
GENETestsABCG4
Target ValidationABCG4
Huge Navigator ABCG4 [HugePedia]
snp3D : Map Gene to Disease64137
BioCentury BCIQABCG4
ClinGenABCG4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64137
Chemical/Pharm GKB GenePA24410
Clinical trialABCG4
Miscellaneous
canSAR (ICR)ABCG4 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineABCG4
EVEXABCG4
GoPubMedABCG4
iHOPABCG4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:54:08 CEST 2017

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