Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ABCG5 (ATP binding cassette subfamily G member 5)

Identity

Alias_namesATP-binding cassette, sub-family G (WHITE), member 5
Alias_symbol (synonym)STSL
Other alias
HGNC (Hugo) ABCG5
LocusID (NCBI) 64240
Atlas_Id 60045
Location 2p21  [Link to chromosome band 2p21]
Location_base_pair Starts at 43812472 and ends at 43838819 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  ow"to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ABCG5   13886
Cards
Entrez_Gene (NCBI)ABCG5  64240  ATP binding cassette subfamily G member 5
AliasesSTSL
GeneCards (Weizmann)ABCG5
Ensembl hg19 (Hinxton)ENSG00000138075 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138075 [Gene_View]  chr2:43812472-43838819 [Contig_View]  ABCG5 [Vega]
ICGC DataPortalENSG00000138075
TCGA cBioPortalABCG5
AceView (NCBI)ABCG5
Genatlas (Paris)ABCG5
WikiGenes64240
SOURCE (Princeton)ABCG5
Genetics Home Reference (NIH)ABCG5
Genomic and cartography
GoldenPath hg38 (UCSC)ABCG5  -     chr2:43812472-43838819 -  2p21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ABCG5  -     2p21   [Description]    (hg19-Feb_2009)
EnsemblABCG5 - 2p21 [CytoView hg19]  ABCG5 - 2p21 [CytoView hg38]
Mapping of homologs : NCBIABCG5 [Mapview hg19]  ABCG5 [Mapview hg38]
OMIM210250   605459   
Gene and transcription
Genbank (Entrez)AF312715 AF320293 AK091997 BC111541 BC111542
RefSeq transcript (Entrez)NM_022436
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ABCG5
Cluster EST : UnigeneHs.132992 [ NCBI ]
CGAP (NCI)Hs.132992
Alternative Splicing GalleryENSG00000138075
Gene ExpressionABCG5 [ NCBI-GEO ]   ABCG5 [ EBI - ARRAY_EXPRESS ]   ABCG5 [ SEEK ]   ABCG5 [ MEM ]
Gene Expression Viewer (FireBrowse)ABCG5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64240
GTEX Portal (Tissue expression)ABCG5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H222   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H222  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H222
Splice isoforms : SwissVarQ9H222
PhosPhoSitePlusQ9H222
Domaine pattern : Prosite (Expaxy)ABC_TRANSPORTER_2 (PS50893)   
Domains : Interpro (EBI)AAA+_ATPase    ABC_2_trans    ABC_transporter-like    P-loop_NTPase   
Domain families : Pfam (Sanger)ABC2_membrane (PF01061)    ABC_tran (PF00005)   
Domain families : Pfam (NCBI)pfam01061    pfam00005   
Domain families : Smart (EMBL)AAA (SM00382)  
Conserved Domain (NCBI)ABCG5
DMDM Disease mutations64240
Blocks (Seattle)ABCG5
PDB (SRS)5DO7   
PDB (PDBSum)5DO7   
PDB (IMB)5DO7   
PDB (RSDB)5DO7   
Structural Biology KnowledgeBase5DO7   
SCOP (Structural Classification of Proteins)5DO7   
CATH (Classification of proteins structures)5DO7   
SuperfamilyQ9H222
Human Protein AtlasENSG00000138075
Peptide AtlasQ9H222
HPRD05678
IPIIPI00007839   IPI00894393   IPI00916326   IPI00974549   
Protein Interaction databases
DIP (DOE-UCLA)Q9H222
IntAct (EBI)Q9H222
FunCoupENSG00000138075
BioGRIDABCG5
STRING (EMBL)ABCG5
ZODIACABCG5
Ontologies - Pathways
QuickGOQ9H222
Ontology : AmiGOprotein binding  ATP binding  plasma membrane  drug transmembrane transport  response to nutrient  excretion  response to ionizing radiation  negative regulation of intestinal phytosterol absorption  sterol transport  apical plasma membrane  ATPase activity  cholesterol transporter activity  intestinal cholesterol absorption  cholesterol efflux  ATPase activity, coupled to transmembrane movement of substances  cholesterol homeostasis  ATP-binding cassette (ABC) transporter complex  receptor complex  negative regulation of intestinal cholesterol absorption  protein heterodimerization activity  transmembrane transport  
Ontology : EGO-EBIprotein binding  ATP binding  plasma membrane  drug transmembrane transport  response to nutrient  excretion  response to ionizing radiation  negative regulation of intestinal phytosterol absorption  sterol transport  apical plasma membrane  ATPase activity  cholesterol transporter activity  intestinal cholesterol absorption  cholesterol efflux  ATPase activity, coupled to transmembrane movement of substances  cholesterol homeostasis  ATP-binding cassette (ABC) transporter complex  receptor complex  negative regulation of intestinal cholesterol absorption  protein heterodimerization activity  transmembrane transport  
Pathways : BIOCARTANuclear Receptors in Lipid Metabolism and Toxicity [Genes]   
Pathways : KEGGABC transporters    Fat digestion and absorption    Bile secretion   
NDEx NetworkABCG5
Atlas of Cancer Signalling NetworkABCG5
Wikipedia pathwaysABCG5
Orthology - Evolution
OrthoDB64240
GeneTree (enSembl)ENSG00000138075
Phylogenetic Trees/Animal Genes : TreeFamABCG5
HOVERGENQ9H222
HOGENOMQ9H222
Homologs : HomoloGeneABCG5
Homology/Alignments : Family Browser (UCSC)ABCG5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerABCG5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ABCG5
dbVarABCG5
ClinVarABCG5
1000_GenomesABCG5 
Exome Variant ServerABCG5
ExAC (Exome Aggregation Consortium)ABCG5 (select the gene name)
Genetic variants : HAPMAP64240
Genomic Variants (DGV)ABCG5 [DGVbeta]
DECIPHERABCG5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisABCG5 
Mutations
ICGC Data PortalABCG5 
TCGA Data PortalABCG5 
Broad Tumor PortalABCG5
OASIS PortalABCG5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICABCG5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDABCG5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ABCG5
DgiDB (Drug Gene Interaction Database)ABCG5
DoCM (Curated mutations)ABCG5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ABCG5 (select a term)
intoGenABCG5
Cancer3DABCG5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM210250    605459   
Orphanet765   
MedgenABCG5
Genetic Testing Registry ABCG5
NextProtQ9H222 [Medical]
TSGene64240
GENETestsABCG5
Target ValidationABCG5
Huge Navigator ABCG5 [HugePedia]
snp3D : Map Gene to Disease64240
BioCentury BCIQABCG5
ClinGenABCG5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64240
Chemical/Pharm GKB GenePA24411
Clinical trialABCG5
Miscellaneous
canSAR (ICR)ABCG5 (select the gene name)
Probes
Litterature
PubMed98 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineABCG5
EVEXABCG5
GoPubMedABCG5
iHOPABCG5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:00:39 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.