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ABHD6 (abhydrolase domain containing 6)

Identity

Other alias-
HGNC (Hugo) ABHD6
LocusID (NCBI) 57406
Atlas_Id 50965
Location 3p14.3  [Link to chromosome band 3p14]
Location_base_pair Starts at 58237502 and ends at 58294736 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABHD6 (3p14.3) / ABHD6 (3p14.3)ABHD6 (3p14.3) / FLNB (3p14.3)ABHD6 (3p14.3) / KLHL24 (3q27.1)
ABHD6 (3p14.3) / LOC100507412 (-)EEF2 (19p13.3) / ABHD6 (3p14.3)RPP14 (3p14.3) / ABHD6 (3p14.3)
ABHD6 3p14.3 / FLNB 3p14.3RPP14 3p14.3 / ABHD6 3p14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ABHD6   21398
Cards
Entrez_Gene (NCBI)ABHD6  57406  abhydrolase domain containing 6
Aliases
GeneCards (Weizmann)ABHD6
Ensembl hg19 (Hinxton)ENSG00000163686 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163686 [Gene_View]  chr3:58237502-58294736 [Contig_View]  ABHD6 [Vega]
ICGC DataPortalENSG00000163686
TCGA cBioPortalABHD6
AceView (NCBI)ABHD6
Genatlas (Paris)ABHD6
WikiGenes57406
SOURCE (Princeton)ABHD6
Genetics Home Reference (NIH)ABHD6
Genomic and cartography
GoldenPath hg38 (UCSC)ABHD6  -     chr3:58237502-58294736 +  3p14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ABHD6  -     3p14.3   [Description]    (hg19-Feb_2009)
EnsemblABHD6 - 3p14.3 [CytoView hg19]  ABHD6 - 3p14.3 [CytoView hg38]
Mapping of homologs : NCBIABHD6 [Mapview hg19]  ABHD6 [Mapview hg38]
OMIM616966   
Gene and transcription
Genbank (Entrez)AF225418 AK092841 AK122983 AK172797 AK225942
RefSeq transcript (Entrez)NM_001320126 NM_020676
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ABHD6
Cluster EST : UnigeneHs.476454 [ NCBI ]
CGAP (NCI)Hs.476454
Alternative Splicing GalleryENSG00000163686
Gene ExpressionABHD6 [ NCBI-GEO ]   ABHD6 [ EBI - ARRAY_EXPRESS ]   ABHD6 [ SEEK ]   ABHD6 [ MEM ]
Gene Expression Viewer (FireBrowse)ABHD6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57406
GTEX Portal (Tissue expression)ABHD6
Human Protein AtlasENSG00000163686-ABHD6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BV23   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BV23  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BV23
Splice isoforms : SwissVarQ9BV23
PhosPhoSitePlusQ9BV23
Domains : Interpro (EBI)AB_hydrolase    AB_hydrolase_1    Epox_hydrolase-like   
Domain families : Pfam (Sanger)Abhydrolase_1 (PF00561)   
Domain families : Pfam (NCBI)pfam00561   
Conserved Domain (NCBI)ABHD6
DMDM Disease mutations57406
Blocks (Seattle)ABHD6
SuperfamilyQ9BV23
Human Protein Atlas [tissue]ENSG00000163686-ABHD6 [tissue]
Peptide AtlasQ9BV23
HPRD12407
IPIIPI00107039   IPI00162707   IPI00946755   IPI00946211   
Protein Interaction databases
DIP (DOE-UCLA)Q9BV23
IntAct (EBI)Q9BV23
FunCoupENSG00000163686
BioGRIDABHD6
STRING (EMBL)ABHD6
ZODIACABHD6
Ontologies - Pathways
QuickGOQ9BV23
Ontology : AmiGOphospholipase activity  mitochondrion  plasma membrane  phospholipid catabolic process  integral component of membrane  negative regulation of cell migration  AMPA glutamate receptor complex  acylglycerol catabolic process  positive regulation of lipid biosynthetic process  acylglycerol lipase activity  acylglycerol lipase activity  long term synaptic depression  extracellular exosome  regulation of endocannabinoid signaling pathway  
Ontology : EGO-EBIphospholipase activity  mitochondrion  plasma membrane  phospholipid catabolic process  integral component of membrane  negative regulation of cell migration  AMPA glutamate receptor complex  acylglycerol catabolic process  positive regulation of lipid biosynthetic process  acylglycerol lipase activity  acylglycerol lipase activity  long term synaptic depression  extracellular exosome  regulation of endocannabinoid signaling pathway  
Pathways : KEGGRetrograde endocannabinoid signaling   
NDEx NetworkABHD6
Atlas of Cancer Signalling NetworkABHD6
Wikipedia pathwaysABHD6
Orthology - Evolution
OrthoDB57406
GeneTree (enSembl)ENSG00000163686
Phylogenetic Trees/Animal Genes : TreeFamABHD6
HOVERGENQ9BV23
HOGENOMQ9BV23
Homologs : HomoloGeneABHD6
Homology/Alignments : Family Browser (UCSC)ABHD6
Gene fusions - Rearrangements
Fusion : MitelmanABHD6/FLNB [3p14.3/3p14.3]  
Fusion : MitelmanRPP14/ABHD6 [3p14.3/3p14.3]  [t(3;3)(p14;p14)]  
Fusion: TCGA_MDACCABHD6 3p14.3 FLNB 3p14.3 KIRC
Fusion: TCGA_MDACCRPP14 3p14.3 ABHD6 3p14.3 SKCM
Tumor Fusion PortalABHD6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerABHD6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ABHD6
dbVarABHD6
ClinVarABHD6
1000_GenomesABHD6 
Exome Variant ServerABHD6
ExAC (Exome Aggregation Consortium)ENSG00000163686
GNOMAD BrowserENSG00000163686
Genetic variants : HAPMAP57406
Genomic Variants (DGV)ABHD6 [DGVbeta]
DECIPHERABHD6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisABHD6 
Mutations
ICGC Data PortalABHD6 
TCGA Data PortalABHD6 
Broad Tumor PortalABHD6
OASIS PortalABHD6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICABHD6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDABHD6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ABHD6
DgiDB (Drug Gene Interaction Database)ABHD6
DoCM (Curated mutations)ABHD6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ABHD6 (select a term)
intoGenABHD6
Cancer3DABHD6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616966   
Orphanet
DisGeNETABHD6
MedgenABHD6
Genetic Testing Registry ABHD6
NextProtQ9BV23 [Medical]
TSGene57406
GENETestsABHD6
Target ValidationABHD6
Huge Navigator ABHD6 [HugePedia]
snp3D : Map Gene to Disease57406
BioCentury BCIQABHD6
ClinGenABHD6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57406
Chemical/Pharm GKB GenePA134916787
Clinical trialABHD6
Miscellaneous
canSAR (ICR)ABHD6 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineABHD6
EVEXABHD6
GoPubMedABHD6
iHOPABHD6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:01:42 CET 2017

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