Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ABLIM2 (actin binding LIM protein family member 2)

Identity

Alias_namesactin binding LIM protein 2
actin binding LIM protein family, member 2
Alias_symbol (synonym)KIAA1808
Other alias-
HGNC (Hugo) ABLIM2
LocusID (NCBI) 84448
Atlas_Id 60063
Location 4p16.1  [Link to chromosome band 4p16]
Location_base_pair Starts at 7965310 and ends at 8158832 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABLIM2 (4p16.1) / PPP2R2C (4p16.1)AFAP1 (4p16.1) / ABLIM2 (4p16.1)CD74 (5q32) / ABLIM2 (4p16.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  ABLIM2/PPP2R2C (4p16)
AFAP1/ABLIM2 (4p16)

External links

Nomenclature
HGNC (Hugo)ABLIM2   19195
Cards
Entrez_Gene (NCBI)ABLIM2  84448  actin binding LIM protein family member 2
Aliases
GeneCards (Weizmann)ABLIM2
Ensembl hg19 (Hinxton)ENSG00000163995 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163995 [Gene_View]  ENSG00000163995 [Sequence]  chr4:7965310-8158832 [Contig_View]  ABLIM2 [Vega]
ICGC DataPortalENSG00000163995
TCGA cBioPortalABLIM2
AceView (NCBI)ABLIM2
Genatlas (Paris)ABLIM2
WikiGenes84448
SOURCE (Princeton)ABLIM2
Genetics Home Reference (NIH)ABLIM2
Genomic and cartography
GoldenPath hg38 (UCSC)ABLIM2  -     chr4:7965310-8158832 -  4p16.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ABLIM2  -     4p16.1   [Description]    (hg19-Feb_2009)
GoldenPathABLIM2 - 4p16.1 [CytoView hg19]  ABLIM2 - 4p16.1 [CytoView hg38]
ImmunoBaseENSG00000163995
Mapping of homologs : NCBIABLIM2 [Mapview hg19]  ABLIM2 [Mapview hg38]
OMIM612544   
Gene and transcription
Genbank (Entrez)AB058711 AJ431609 AJ748600 AJ748601 AK094754
RefSeq transcript (Entrez)NM_001130083 NM_001130084 NM_001130085 NM_001130086 NM_001130087 NM_001130088 NM_001286688 NM_032432
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ABLIM2
Alternative Splicing GalleryENSG00000163995
Gene ExpressionABLIM2 [ NCBI-GEO ]   ABLIM2 [ EBI - ARRAY_EXPRESS ]   ABLIM2 [ SEEK ]   ABLIM2 [ MEM ]
Gene Expression Viewer (FireBrowse)ABLIM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84448
GTEX Portal (Tissue expression)ABLIM2
Human Protein AtlasENSG00000163995-ABLIM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6H8Q1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6H8Q1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6H8Q1
Splice isoforms : SwissVarQ6H8Q1
PhosPhoSitePlusQ6H8Q1
Domaine pattern : Prosite (Expaxy)HP (PS51089)    LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (EBI)ABLIM2    AbLIM_anchor    Villin_headpiece    Villin_headpiece_dom_sf    Znf_LIM   
Domain families : Pfam (Sanger)AbLIM_anchor (PF16182)    LIM (PF00412)    VHP (PF02209)   
Domain families : Pfam (NCBI)pfam16182    pfam00412    pfam02209   
Domain families : Smart (EMBL)LIM (SM00132)  VHP (SM00153)  
Conserved Domain (NCBI)ABLIM2
DMDM Disease mutations84448
Blocks (Seattle)ABLIM2
PDB (RSDB)1V6G    1WIG    2L3X   
PDB Europe1V6G    1WIG    2L3X   
PDB (PDBSum)1V6G    1WIG    2L3X   
PDB (IMB)1V6G    1WIG    2L3X   
Structural Biology KnowledgeBase1V6G    1WIG    2L3X   
SCOP (Structural Classification of Proteins)1V6G    1WIG    2L3X   
CATH (Classification of proteins structures)1V6G    1WIG    2L3X   
SuperfamilyQ6H8Q1
Human Protein Atlas [tissue]ENSG00000163995-ABLIM2 [tissue]
Peptide AtlasQ6H8Q1
IPIIPI00434484   IPI00892702   IPI00187164   IPI00167702   IPI00479275   IPI00761095   IPI00940416   IPI01011329   IPI01010741   IPI01013991   IPI00761132   IPI00442838   IPI00902561   IPI00910569   IPI00968101   
Protein Interaction databases
DIP (DOE-UCLA)Q6H8Q1
IntAct (EBI)Q6H8Q1
FunCoupENSG00000163995
BioGRIDABLIM2
STRING (EMBL)ABLIM2
ZODIACABLIM2
Ontologies - Pathways
QuickGOQ6H8Q1
Ontology : AmiGOcytoplasm  transcription, DNA-templated  actin cytoskeleton  actin cytoskeleton  lamellipodium assembly  actin cytoskeleton organization  metal ion binding  actin filament binding  
Ontology : EGO-EBIcytoplasm  transcription, DNA-templated  actin cytoskeleton  actin cytoskeleton  lamellipodium assembly  actin cytoskeleton organization  metal ion binding  actin filament binding  
Pathways : KEGGAxon guidance   
NDEx NetworkABLIM2
Atlas of Cancer Signalling NetworkABLIM2
Wikipedia pathwaysABLIM2
Orthology - Evolution
OrthoDB84448
GeneTree (enSembl)ENSG00000163995
Phylogenetic Trees/Animal Genes : TreeFamABLIM2
HOGENOMQ6H8Q1
Homologs : HomoloGeneABLIM2
Homology/Alignments : Family Browser (UCSC)ABLIM2
Gene fusions - Rearrangements
Fusion : QuiverABLIM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerABLIM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ABLIM2
dbVarABLIM2
ClinVarABLIM2
1000_GenomesABLIM2 
Exome Variant ServerABLIM2
ExAC (Exome Aggregation Consortium)ENSG00000163995
GNOMAD BrowserENSG00000163995
Varsome BrowserABLIM2
Genetic variants : HAPMAP84448
Genomic Variants (DGV)ABLIM2 [DGVbeta]
DECIPHERABLIM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisABLIM2 
Mutations
ICGC Data PortalABLIM2 
TCGA Data PortalABLIM2 
Broad Tumor PortalABLIM2
OASIS PortalABLIM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICABLIM2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DABLIM2
Mutations and Diseases : HGMDABLIM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ABLIM2
DgiDB (Drug Gene Interaction Database)ABLIM2
DoCM (Curated mutations)ABLIM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ABLIM2 (select a term)
intoGenABLIM2
Cancer3DABLIM2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612544   
Orphanet
DisGeNETABLIM2
MedgenABLIM2
Genetic Testing Registry ABLIM2
NextProtQ6H8Q1 [Medical]
TSGene84448
GENETestsABLIM2
Target ValidationABLIM2
Huge Navigator ABLIM2 [HugePedia]
snp3D : Map Gene to Disease84448
BioCentury BCIQABLIM2
ClinGenABLIM2
Clinical trials, drugs, therapy
Protein Interactions : CTD84448
Pharm GKB GenePA134940437
Clinical trialABLIM2
Miscellaneous
canSAR (ICR)ABLIM2 (select the gene name)
HarmonizomeABLIM2
DataMed IndexABLIM2
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineABLIM2
EVEXABLIM2
GoPubMedABLIM2
iHOPABLIM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Jun 30 19:33:48 CEST 2020
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