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ACAA1 (acetyl-CoA acyltransferase 1)

Identity

Alias_namesacetyl-Coenzyme A acyltransferase 1
Other aliasACAA
PTHIO
THIO
HGNC (Hugo) ACAA1
LocusID (NCBI) 30
Atlas_Id 60068
Location 3p22.2  [Link to chromosome band 3p22]
Location_base_pair Starts at 38164201 and ends at 38178733 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ACAA1 (3p22.2) / ACAA1 (3p22.2)PYGB (20p11.21) / ACAA1 (3p22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACAA1   82
Cards
Entrez_Gene (NCBI)ACAA1  30  acetyl-CoA acyltransferase 1
AliasesACAA; PTHIO; THIO
GeneCards (Weizmann)ACAA1
Ensembl hg19 (Hinxton)ENSG00000060971 [Gene_View]  chr3:38164201-38178733 [Contig_View]  ACAA1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000060971 [Gene_View]  chr3:38164201-38178733 [Contig_View]  ACAA1 [Vega]
ICGC DataPortalENSG00000060971
TCGA cBioPortalACAA1
AceView (NCBI)ACAA1
Genatlas (Paris)ACAA1
WikiGenes30
SOURCE (Princeton)ACAA1
Genetics Home Reference (NIH)ACAA1
Genomic and cartography
GoldenPath hg19 (UCSC)ACAA1  -     chr3:38164201-38178733 -  3p22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ACAA1  -     3p22.2   [Description]    (hg38-Dec_2013)
EnsemblACAA1 - 3p22.2 [CytoView hg19]  ACAA1 - 3p22.2 [CytoView hg38]
Mapping of homologs : NCBIACAA1 [Mapview hg19]  ACAA1 [Mapview hg38]
OMIM604054   
Gene and transcription
Genbank (Entrez)AF035295 AK025138 AK127051 AK293716 AK301056
RefSeq transcript (Entrez)NM_001130410 NM_001607
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_023225 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)ACAA1
Cluster EST : UnigeneHs.643487 [ NCBI ]
CGAP (NCI)Hs.643487
Alternative Splicing GalleryENSG00000060971
Gene ExpressionACAA1 [ NCBI-GEO ]   ACAA1 [ EBI - ARRAY_EXPRESS ]   ACAA1 [ SEEK ]   ACAA1 [ MEM ]
Gene Expression Viewer (FireBrowse)ACAA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)30
GTEX Portal (Tissue expression)ACAA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09110   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09110  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09110
Splice isoforms : SwissVarP09110
Catalytic activity : Enzyme2.3.1.16 [ Enzyme-Expasy ]   2.3.1.162.3.1.16 [ IntEnz-EBI ]   2.3.1.16 [ BRENDA ]   2.3.1.16 [ KEGG ]   
PhosPhoSitePlusP09110
Domaine pattern : Prosite (Expaxy)THIOLASE_1 (PS00098)    THIOLASE_2 (PS00737)    THIOLASE_3 (PS00099)   
Domains : Interpro (EBI)Thiolase    Thiolase-like    Thiolase-like_subgr    Thiolase_acyl_enz_int_AS    Thiolase_AS    Thiolase_C    Thiolase_CS    Thiolase_N   
Domain families : Pfam (Sanger)Thiolase_C (PF02803)    Thiolase_N (PF00108)   
Domain families : Pfam (NCBI)pfam02803    pfam00108   
Conserved Domain (NCBI)ACAA1
DMDM Disease mutations30
Blocks (Seattle)ACAA1
PDB (SRS)2IIK   
PDB (PDBSum)2IIK   
PDB (IMB)2IIK   
PDB (RSDB)2IIK   
Structural Biology KnowledgeBase2IIK   
SCOP (Structural Classification of Proteins)2IIK   
CATH (Classification of proteins structures)2IIK   
SuperfamilyP09110
Human Protein AtlasENSG00000060971
Peptide AtlasP09110
HPRD06815
IPIIPI00012828   IPI00790196   IPI01010885   IPI00303933   IPI00011522   IPI00789589   IPI00924606   IPI00927496   IPI00926442   
Protein Interaction databases
DIP (DOE-UCLA)P09110
IntAct (EBI)P09110
FunCoupENSG00000060971
BioGRIDACAA1
STRING (EMBL)ACAA1
ZODIACACAA1
Ontologies - Pathways
QuickGOP09110
Ontology : AmiGOvery long-chain fatty acid metabolic process  acetyl-CoA C-acyltransferase activity  protein binding  peroxisome  peroxisomal matrix  fatty acid beta-oxidation  bile acid metabolic process  membrane  palmitoyl-CoA oxidase activity  fatty acid beta-oxidation using acyl-CoA oxidase  unsaturated fatty acid metabolic process  alpha-linolenic acid metabolic process  intracellular membrane-bounded organelle  cellular lipid metabolic process  small molecule metabolic process  
Ontology : EGO-EBIvery long-chain fatty acid metabolic process  acetyl-CoA C-acyltransferase activity  protein binding  peroxisome  peroxisomal matrix  fatty acid beta-oxidation  bile acid metabolic process  membrane  palmitoyl-CoA oxidase activity  fatty acid beta-oxidation using acyl-CoA oxidase  unsaturated fatty acid metabolic process  alpha-linolenic acid metabolic process  intracellular membrane-bounded organelle  cellular lipid metabolic process  small molecule metabolic process  
Pathways : KEGGFatty acid degradation    Valine, leucine and isoleucine degradation    alpha-Linolenic acid metabolism    Biosynthesis of unsaturated fatty acids    PPAR signaling pathway    Peroxisome   
NDEx NetworkACAA1
Atlas of Cancer Signalling NetworkACAA1
Wikipedia pathwaysACAA1
Orthology - Evolution
OrthoDB30
GeneTree (enSembl)ENSG00000060971
Phylogenetic Trees/Animal Genes : TreeFamACAA1
HOVERGENP09110
HOGENOMP09110
Homologs : HomoloGeneACAA1
Homology/Alignments : Family Browser (UCSC)ACAA1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACAA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACAA1
dbVarACAA1
ClinVarACAA1
1000_GenomesACAA1 
Exome Variant ServerACAA1
ExAC (Exome Aggregation Consortium)ACAA1 (select the gene name)
Genetic variants : HAPMAP30
Genomic Variants (DGV)ACAA1 [DGVbeta]
DECIPHER (Syndromes)3:38164201-38178733  ENSG00000060971
CONAN: Copy Number AnalysisACAA1 
Mutations
ICGC Data PortalACAA1 
TCGA Data PortalACAA1 
Broad Tumor PortalACAA1
OASIS PortalACAA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACAA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACAA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ACAA1
DgiDB (Drug Gene Interaction Database)ACAA1
DoCM (Curated mutations)ACAA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACAA1 (select a term)
intoGenACAA1
Cancer3DACAA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604054   
Orphanet
MedgenACAA1
Genetic Testing Registry ACAA1
NextProtP09110 [Medical]
TSGene30
GENETestsACAA1
Huge Navigator ACAA1 [HugePedia]
snp3D : Map Gene to Disease30
BioCentury BCIQACAA1
ClinGenACAA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD30
Chemical/Pharm GKB GenePA24419
Clinical trialACAA1
Miscellaneous
canSAR (ICR)ACAA1 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACAA1
EVEXACAA1
GoPubMedACAA1
iHOPACAA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:53:26 CET 2017

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