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ACAD8 (acyl-CoA dehydrogenase family, member 8)

Identity

Alias_namesacyl-Coenzyme A dehydrogenase family, member 8
acyl-CoA dehydrogenase family, member 8
Other aliasACAD-8
ARC42
HGNC (Hugo) ACAD8
LocusID (NCBI) 27034
Atlas_Id 60070
Location 11q25  [Link to chromosome band 11q25]
Location_base_pair Starts at 134123434 and ends at 134135746 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ACAD8 (11q25) / GLB1L3 (11q25)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACAD8   87
LRG (Locus Reference Genomic)LRG_448
Cards
Entrez_Gene (NCBI)ACAD8  27034  acyl-CoA dehydrogenase family, member 8
AliasesACAD-8; ARC42
GeneCards (Weizmann)ACAD8
Ensembl hg19 (Hinxton)ENSG00000151498 [Gene_View]  chr11:134123434-134135746 [Contig_View]  ACAD8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000151498 [Gene_View]  chr11:134123434-134135746 [Contig_View]  ACAD8 [Vega]
ICGC DataPortalENSG00000151498
TCGA cBioPortalACAD8
AceView (NCBI)ACAD8
Genatlas (Paris)ACAD8
WikiGenes27034
SOURCE (Princeton)ACAD8
Genetics Home Reference (NIH)ACAD8
Genomic and cartography
GoldenPath hg19 (UCSC)ACAD8  -     chr11:134123434-134135746 +  11q25   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ACAD8  -     11q25   [Description]    (hg38-Dec_2013)
EnsemblACAD8 - 11q25 [CytoView hg19]  ACAD8 - 11q25 [CytoView hg38]
Mapping of homologs : NCBIACAD8 [Mapview hg19]  ACAD8 [Mapview hg38]
OMIM604773   611283   
Gene and transcription
Genbank (Entrez)AB209538 AF126245 AK000359 AK026243 AK074640
RefSeq transcript (Entrez)NM_014384
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_015842 NT_033899 NW_004929381
Consensus coding sequences : CCDS (NCBI)ACAD8
Cluster EST : UnigeneHs.14791 [ NCBI ]
CGAP (NCI)Hs.14791
Alternative Splicing GalleryENSG00000151498
Gene ExpressionACAD8 [ NCBI-GEO ]   ACAD8 [ EBI - ARRAY_EXPRESS ]   ACAD8 [ SEEK ]   ACAD8 [ MEM ]
Gene Expression Viewer (FireBrowse)ACAD8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27034
GTEX Portal (Tissue expression)ACAD8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKU7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKU7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKU7
Splice isoforms : SwissVarQ9UKU7
Catalytic activity : Enzyme1.3.99.- [ Enzyme-Expasy ]   1.3.99.-1.3.99.- [ IntEnz-EBI ]   1.3.99.- [ BRENDA ]   1.3.99.- [ KEGG ]   
PhosPhoSitePlusQ9UKU7
Domaine pattern : Prosite (Expaxy)ACYL_COA_DH_1 (PS00072)   
Domains : Interpro (EBI)Acyl-CoA_DH_CS    Acyl-CoA_Oxase/DH_cen-dom    AcylCo_DH/oxidase_C    AcylCoA_DH/ox_N    AcylCoA_DH/oxidase_NM_dom   
Domain families : Pfam (Sanger)Acyl-CoA_dh_1 (PF00441)    Acyl-CoA_dh_M (PF02770)    Acyl-CoA_dh_N (PF02771)   
Domain families : Pfam (NCBI)pfam00441    pfam02770    pfam02771   
Conserved Domain (NCBI)ACAD8
DMDM Disease mutations27034
Blocks (Seattle)ACAD8
PDB (SRS)1RX0   
PDB (PDBSum)1RX0   
PDB (IMB)1RX0   
PDB (RSDB)1RX0   
Structural Biology KnowledgeBase1RX0   
SCOP (Structural Classification of Proteins)1RX0   
CATH (Classification of proteins structures)1RX0   
SuperfamilyQ9UKU7
Human Protein AtlasENSG00000151498
Peptide AtlasQ9UKU7
HPRD11985
IPIIPI00747159   IPI00922810   IPI00922442   IPI00445796   IPI00556276   IPI00984944   IPI00984378   IPI00446874   IPI00984390   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKU7
IntAct (EBI)Q9UKU7
FunCoupENSG00000151498
BioGRIDACAD8
STRING (EMBL)ACAD8
ZODIACACAD8
Ontologies - Pathways
QuickGOQ9UKU7
Ontology : AmiGOacyl-CoA dehydrogenase activity  mitochondrial matrix  transcription, DNA-templated  regulation of transcription, DNA-templated  valine catabolic process  lipid metabolic process  branched-chain amino acid catabolic process  cellular nitrogen compound metabolic process  small molecule metabolic process  flavin adenine dinucleotide binding  oxidation-reduction process  
Ontology : EGO-EBIacyl-CoA dehydrogenase activity  mitochondrial matrix  transcription, DNA-templated  regulation of transcription, DNA-templated  valine catabolic process  lipid metabolic process  branched-chain amino acid catabolic process  cellular nitrogen compound metabolic process  small molecule metabolic process  flavin adenine dinucleotide binding  oxidation-reduction process  
Pathways : KEGGValine, leucine and isoleucine degradation   
NDEx NetworkACAD8
Atlas of Cancer Signalling NetworkACAD8
Wikipedia pathwaysACAD8
Orthology - Evolution
OrthoDB27034
GeneTree (enSembl)ENSG00000151498
Phylogenetic Trees/Animal Genes : TreeFamACAD8
HOVERGENQ9UKU7
HOGENOMQ9UKU7
Homologs : HomoloGeneACAD8
Homology/Alignments : Family Browser (UCSC)ACAD8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACAD8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACAD8
dbVarACAD8
ClinVarACAD8
1000_GenomesACAD8 
Exome Variant ServerACAD8
ExAC (Exome Aggregation Consortium)ACAD8 (select the gene name)
Genetic variants : HAPMAP27034
Genomic Variants (DGV)ACAD8 [DGVbeta]
DECIPHER (Syndromes)11:134123434-134135746  ENSG00000151498
CONAN: Copy Number AnalysisACAD8 
Mutations
ICGC Data PortalACAD8 
TCGA Data PortalACAD8 
Broad Tumor PortalACAD8
OASIS PortalACAD8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACAD8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACAD8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ACAD8
DgiDB (Drug Gene Interaction Database)ACAD8
DoCM (Curated mutations)ACAD8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACAD8 (select a term)
intoGenACAD8
Cancer3DACAD8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604773    611283   
Orphanet11185   
MedgenACAD8
Genetic Testing Registry ACAD8
NextProtQ9UKU7 [Medical]
TSGene27034
GENETestsACAD8
Huge Navigator ACAD8 [HugePedia]
snp3D : Map Gene to Disease27034
BioCentury BCIQACAD8
ClinGenACAD8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27034
Chemical/Pharm GKB GenePA24423
Clinical trialACAD8
Miscellaneous
canSAR (ICR)ACAD8 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACAD8
EVEXACAD8
GoPubMedACAD8
iHOPACAD8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:53:26 CET 2017

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