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ACADSB (acyl-CoA dehydrogenase, short/branched chain)

Identity

Alias_namesacyl-Coenzyme A dehydrogenase, short/branched chain
Alias_symbol (synonym)SBCAD
ACAD7
Other alias2-MEBCAD
HGNC (Hugo) ACADSB
LocusID (NCBI) 36
Atlas_Id 60075
Location 10q26.13  [Link to chromosome band 10q26]
Location_base_pair Starts at 124768429 and ends at 124817806 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CASP6 (4q25) / ACADSB (10q26.13)FAM127A (Xq26.3) / ACADSB (10q26.13)FGFR2 (10q26.13) / ACADSB (10q26.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACADSB   91
LRG (Locus Reference Genomic)LRG_451
Cards
Entrez_Gene (NCBI)ACADSB  36  acyl-CoA dehydrogenase, short/branched chain
Aliases2-MEBCAD; ACAD7; SBCAD
GeneCards (Weizmann)ACADSB
Ensembl hg19 (Hinxton)ENSG00000196177 [Gene_View]  chr10:124768429-124817806 [Contig_View]  ACADSB [Vega]
Ensembl hg38 (Hinxton)ENSG00000196177 [Gene_View]  chr10:124768429-124817806 [Contig_View]  ACADSB [Vega]
ICGC DataPortalENSG00000196177
TCGA cBioPortalACADSB
AceView (NCBI)ACADSB
Genatlas (Paris)ACADSB
WikiGenes36
SOURCE (Princeton)ACADSB
Genetics Home Reference (NIH)ACADSB
Genomic and cartography
GoldenPath hg19 (UCSC)ACADSB  -     chr10:124768429-124817806 +  10q26.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ACADSB  -     10q26.13   [Description]    (hg38-Dec_2013)
EnsemblACADSB - 10q26.13 [CytoView hg19]  ACADSB - 10q26.13 [CytoView hg38]
Mapping of homologs : NCBIACADSB [Mapview hg19]  ACADSB [Mapview hg38]
OMIM600301   610006   
Gene and transcription
Genbank (Entrez)AK298638 AK314241 AL831821 BC013756 BC020931
RefSeq transcript (Entrez)NM_001609
RefSeq genomic (Entrez)NC_000010 NC_018921 NG_008003 NT_030059 NW_004929376
Consensus coding sequences : CCDS (NCBI)ACADSB
Cluster EST : UnigeneHs.81934 [ NCBI ]
CGAP (NCI)Hs.81934
Alternative Splicing GalleryENSG00000196177
Gene ExpressionACADSB [ NCBI-GEO ]   ACADSB [ EBI - ARRAY_EXPRESS ]   ACADSB [ SEEK ]   ACADSB [ MEM ]
Gene Expression Viewer (FireBrowse)ACADSB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)36
GTEX Portal (Tissue expression)ACADSB
Protein : pattern, domain, 3D structure
UniProt/SwissProtP45954   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP45954  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP45954
Splice isoforms : SwissVarP45954
Catalytic activity : Enzyme1.3.8.5 [ Enzyme-Expasy ]   1.3.8.51.3.8.5 [ IntEnz-EBI ]   1.3.8.5 [ BRENDA ]   1.3.8.5 [ KEGG ]   
PhosPhoSitePlusP45954
Domaine pattern : Prosite (Expaxy)ACYL_COA_DH_1 (PS00072)    ACYL_COA_DH_2 (PS00073)   
Domains : Interpro (EBI)Acyl-CoA_DH_CS    Acyl-CoA_Oxase/DH_cen-dom    AcylCo_DH/oxidase_C    AcylCoA_DH/ox_N    AcylCoA_DH/oxidase_NM_dom   
Domain families : Pfam (Sanger)Acyl-CoA_dh_1 (PF00441)    Acyl-CoA_dh_M (PF02770)    Acyl-CoA_dh_N (PF02771)   
Domain families : Pfam (NCBI)pfam00441    pfam02770    pfam02771   
Conserved Domain (NCBI)ACADSB
DMDM Disease mutations36
Blocks (Seattle)ACADSB
PDB (SRS)2JIF   
PDB (PDBSum)2JIF   
PDB (IMB)2JIF   
PDB (RSDB)2JIF   
Structural Biology KnowledgeBase2JIF   
SCOP (Structural Classification of Proteins)2JIF   
CATH (Classification of proteins structures)2JIF   
SuperfamilyP45954
Human Protein AtlasENSG00000196177
Peptide AtlasP45954
HPRD02626
IPIIPI00024623   IPI00514033   IPI01012473   
Protein Interaction databases
DIP (DOE-UCLA)P45954
IntAct (EBI)P45954
FunCoupENSG00000196177
BioGRIDACADSB
STRING (EMBL)ACADSB
ZODIACACADSB
Ontologies - Pathways
QuickGOP45954
Ontology : AmiGOacyl-CoA dehydrogenase activity  mitochondrion  mitochondrial matrix  fatty acid metabolic process  branched-chain amino acid catabolic process  cellular nitrogen compound metabolic process  small molecule metabolic process  flavin adenine dinucleotide binding  oxidation-reduction process  extracellular exosome  
Ontology : EGO-EBIacyl-CoA dehydrogenase activity  mitochondrion  mitochondrial matrix  fatty acid metabolic process  branched-chain amino acid catabolic process  cellular nitrogen compound metabolic process  small molecule metabolic process  flavin adenine dinucleotide binding  oxidation-reduction process  extracellular exosome  
Pathways : KEGGFatty acid degradation    Valine, leucine and isoleucine degradation   
NDEx NetworkACADSB
Atlas of Cancer Signalling NetworkACADSB
Wikipedia pathwaysACADSB
Orthology - Evolution
OrthoDB36
GeneTree (enSembl)ENSG00000196177
Phylogenetic Trees/Animal Genes : TreeFamACADSB
HOVERGENP45954
HOGENOMP45954
Homologs : HomoloGeneACADSB
Homology/Alignments : Family Browser (UCSC)ACADSB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACADSB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACADSB
dbVarACADSB
ClinVarACADSB
1000_GenomesACADSB 
Exome Variant ServerACADSB
ExAC (Exome Aggregation Consortium)ACADSB (select the gene name)
Genetic variants : HAPMAP36
Genomic Variants (DGV)ACADSB [DGVbeta]
DECIPHER (Syndromes)10:124768429-124817806  ENSG00000196177
CONAN: Copy Number AnalysisACADSB 
Mutations
ICGC Data PortalACADSB 
TCGA Data PortalACADSB 
Broad Tumor PortalACADSB
OASIS PortalACADSB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACADSB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACADSB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ACADSB
DgiDB (Drug Gene Interaction Database)ACADSB
DoCM (Curated mutations)ACADSB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACADSB (select a term)
intoGenACADSB
Cancer3DACADSB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600301    610006   
Orphanet11183   
MedgenACADSB
Genetic Testing Registry ACADSB
NextProtP45954 [Medical]
TSGene36
GENETestsACADSB
Huge Navigator ACADSB [HugePedia]
snp3D : Map Gene to Disease36
BioCentury BCIQACADSB
ClinGenACADSB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD36
Chemical/Pharm GKB GenePA24427
Clinical trialACADSB
Miscellaneous
canSAR (ICR)ACADSB (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACADSB
EVEXACADSB
GoPubMedACADSB
iHOPACADSB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:53:27 CET 2017

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