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ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)

Identity

Alias_namesCENTB1
centaurin
Alias_symbol (synonym)KIAA0050
Other alias
HGNC (Hugo) ACAP1
LocusID (NCBI) 9744
Atlas_Id 52747
Location 17p13.1  [Link to chromosome band 17p13]
Location_base_pair Starts at 7239848 and ends at 7254793 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CEP131 (17q25.3) / ACAP1 (17p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ACAP1   16467
Cards
Entrez_Gene (NCBI)ACAP1  9744  ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
AliasesCENTB1
GeneCards (Weizmann)ACAP1
Ensembl hg19 (Hinxton)ENSG00000072818 [Gene_View]  chr17:7239848-7254793 [Contig_View]  ACAP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000072818 [Gene_View]  chr17:7239848-7254793 [Contig_View]  ACAP1 [Vega]
ICGC DataPortalENSG00000072818
TCGA cBioPortalACAP1
AceView (NCBI)ACAP1
Genatlas (Paris)ACAP1
WikiGenes9744
SOURCE (Princeton)ACAP1
Genetics Home Reference (NIH)ACAP1
Genomic and cartography
GoldenPath hg19 (UCSC)ACAP1  -     chr17:7239848-7254793 +  17p13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ACAP1  -     17p13.1   [Description]    (hg38-Dec_2013)
EnsemblACAP1 - 17p13.1 [CytoView hg19]  ACAP1 - 17p13.1 [CytoView hg38]
Mapping of homologs : NCBIACAP1 [Mapview hg19]  ACAP1 [Mapview hg38]
OMIM607763   
Gene and transcription
Genbank (Entrez)AA356620 BC018543 BT009788 D30758 DQ891719
RefSeq transcript (Entrez)NM_014716
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)ACAP1
Cluster EST : UnigeneHs.337242 [ NCBI ]
CGAP (NCI)Hs.337242
Alternative Splicing GalleryENSG00000072818
Gene ExpressionACAP1 [ NCBI-GEO ]   ACAP1 [ EBI - ARRAY_EXPRESS ]   ACAP1 [ SEEK ]   ACAP1 [ MEM ]
Gene Expression Viewer (FireBrowse)ACAP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9744
GTEX Portal (Tissue expression)ACAP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15027   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15027  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15027
Splice isoforms : SwissVarQ15027
PhosPhoSitePlusQ15027
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)    ARFGAP (PS50115)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)AH/BAR-dom    Ankyrin_rpt    Ankyrin_rpt-contain_dom    ArfGAP    PH_dom-like    PH_domain    PLipase_C_PInositol-sp_X_dom   
Domain families : Pfam (Sanger)ArfGap (PF01412)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam01412    pfam00169   
Domain families : Smart (EMBL)ANK (SM00248)  ArfGap (SM00105)  PH (SM00233)  
Conserved Domain (NCBI)ACAP1
DMDM Disease mutations9744
Blocks (Seattle)ACAP1
PDB (SRS)3JUE    3T9K    4CKG    4CKH    4F1P    4NSW   
PDB (PDBSum)3JUE    3T9K    4CKG    4CKH    4F1P    4NSW   
PDB (IMB)3JUE    3T9K    4CKG    4CKH    4F1P    4NSW   
PDB (RSDB)3JUE    3T9K    4CKG    4CKH    4F1P    4NSW   
Structural Biology KnowledgeBase3JUE    3T9K    4CKG    4CKH    4F1P    4NSW   
SCOP (Structural Classification of Proteins)3JUE    3T9K    4CKG    4CKH    4F1P    4NSW   
CATH (Classification of proteins structures)3JUE    3T9K    4CKG    4CKH    4F1P    4NSW   
SuperfamilyQ15027
Human Protein AtlasENSG00000072818
Peptide AtlasQ15027
HPRD08474
IPIIPI00014199   
Protein Interaction databases
DIP (DOE-UCLA)Q15027
IntAct (EBI)Q15027
FunCoupENSG00000072818
BioGRIDACAP1
STRING (EMBL)ACAP1
ZODIACACAP1
Ontologies - Pathways
QuickGOQ15027
Ontology : AmiGOGTPase activator activity  protein binding  protein transport  membrane  positive regulation of GTPase activity  metal ion binding  recycling endosome membrane  
Ontology : EGO-EBIGTPase activator activity  protein binding  protein transport  membrane  positive regulation of GTPase activity  metal ion binding  recycling endosome membrane  
Pathways : KEGGEndocytosis   
NDEx NetworkACAP1
Atlas of Cancer Signalling NetworkACAP1
Wikipedia pathwaysACAP1
Orthology - Evolution
OrthoDB9744
GeneTree (enSembl)ENSG00000072818
Phylogenetic Trees/Animal Genes : TreeFamACAP1
HOVERGENQ15027
HOGENOMQ15027
Homologs : HomoloGeneACAP1
Homology/Alignments : Family Browser (UCSC)ACAP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerACAP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ACAP1
dbVarACAP1
ClinVarACAP1
1000_GenomesACAP1 
Exome Variant ServerACAP1
ExAC (Exome Aggregation Consortium)ACAP1 (select the gene name)
Genetic variants : HAPMAP9744
Genomic Variants (DGV)ACAP1 [DGVbeta]
DECIPHER (Syndromes)17:7239848-7254793  ENSG00000072818
CONAN: Copy Number AnalysisACAP1 
Mutations
ICGC Data PortalACAP1 
TCGA Data PortalACAP1 
Broad Tumor PortalACAP1
OASIS PortalACAP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICACAP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDACAP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ACAP1
DgiDB (Drug Gene Interaction Database)ACAP1
DoCM (Curated mutations)ACAP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ACAP1 (select a term)
intoGenACAP1
Cancer3DACAP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607763   
Orphanet
MedgenACAP1
Genetic Testing Registry ACAP1
NextProtQ15027 [Medical]
TSGene9744
GENETestsACAP1
Huge Navigator ACAP1 [HugePedia]
snp3D : Map Gene to Disease9744
BioCentury BCIQACAP1
ClinGenACAP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9744
Chemical/Pharm GKB GenePA26406
Clinical trialACAP1
Miscellaneous
canSAR (ICR)ACAP1 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineACAP1
EVEXACAP1
GoPubMedACAP1
iHOPACAP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:54:34 CET 2017

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